Journal of Experimental and Clinical SurgeryJournal of Experimental and Clinical Surgery2070-478X2409-143XVoronezh State Medical University23610.18499/2070-478X-2013-6-2-254-256UnknownNon-Hodgkin Lymphoma on the Base of Autoimmune TireoiditPh.D., Krasnodar City Hospital №2, Department of Endocrine surgeryauthor@vestnik-surgery.comprofessor, D.Sc., Rostov State Medical University, Head of the Department of General Surgeryauthor@vestnik-surgery.comCity Hospital №2, Krasnodar, Russian FederationRostov State Medical University, Rostov-on-Don, Russian Federaion24062013622542562804201628042016Copyright © 2013, ., .2013The article discussed some problems in diagnostics and specific issues of treatment of Hodgkins and non-Hodgkins lymphomas (NHL) of thyroid gland, more than 30 congenital diseases, growing from mature B, T and NK-cells, which are different in morphology, clinical symptoms and treatment’s results, especially in case of combination of NHL and autoimmune thyroiditis. Correlation between autoimmune thyroiditis and the development of primary non-Hodgkin's lymphoma of the thyroid gland remains unclear. Authors pointed unsatisfaction with cytological methods of diagnostics. The authors recommend a comprehensive study of patients for diagnostic of thyroid gland diseases, including ultrasonic needle biopsy with cytology analysis, CT scan of the thyroid gland and anterior mediastinum, thyroid gland ultrasound, scintigraphy of the thyroid gland, hormonal status investigation. Open biopsy following by histological examination and necessity of differentiation with non- differentiated cancer of thyroid gland, autoimmune thyroiditis and Ridel’s goiter are also recommended. In case of rapid growth of the thyroid gland, significant heterogeneity of structure, absence of organ’s mobility in combination with cytologically proved "Hurthle’s autoimmune thyroiditis", it is necessary to exclude NHL. Besides surgical treatment authors recommend chemotherapy.Hodgkin's and Non-Hodgkin's lymphomasautoimmune tireoditdiagnosticstreatmentХоджкинская и неходжкинская лимфомадиагностикалечение[1. Kalinin A.P., Zlatkina A.R., Golenkov A.K., Kamynina][T.S. Pervichnaya limfosarkoma shchitovidnoy zhelezy [Primary lymphosarcoma of the thyroid gland]. Voprosy][onkologii, 1988; 3: 269-276. – (In Russian).][2. Paches A.I., Propp R.M. Rak shchitovidnoi zhelezy [Cancer][of the thyroid gland]. Moscow, 1984. 320 p. – (In Russian).][3. Privalov V.A. Khirurgicheskaia taktika pri zabolevaniiakh][shchitovidnoi zhelezy v zavisimosti ot vyrazhennosti][antitireoidnoi autoimmunnoi agressii. Avtoref. kand.][dissertatsii [Surgical tactics for diseases of the thyroid][gland, depending on the severity of antithyroid autoimmune][aggression. Synopsis cand. med. sci. diss.]. Kuibyshev,][1989; 31 p. – (In Russian).][4. Rumiantsev P.O., Il'in A.A., Rumiantseva U.V., Saenko][V.A. Rak shchitovidnoi zhelezy. Sovremennye podkhody][k diagnostike i lecheniiu [Cancer of the thyroid gland.][Modern approaches to diagnosis and treatment]. Moscow,][2009. 447 p. – (In Russian).][5. Khmel'nitskii O.K. Tsitologicheskaia i gistologicheskaia][diagnostika zabolevanii shchitovidnoi zhelezy [Cytological][and histological diagnosis of diseases of the thyroid gland].][Saint-Petersburg, SOTIS Publ., 2002. 288 p. – (In Russian).][6. Shulutko A.M., Semikov V.I., Ivanova N.A. ul'trazvukovoy][metody issledovaniya i punktsionnoy biopsii v diagnostike][shchitovidnoy khirurgii raka [Ultrasonic][methods of research and puncture biopsy in the diagnosis][of thyroid cancer surgery]. Khirurgiia, 2002; 5: 7–12. – (In][Russian).][7. Hernandez J.A., Reth P., Ballester E. Linfoma de Primaria][tiroides kon infiltración de la Medula OSEA u del' tsentral'nyy sistemanerviosa [Limfomaprimaria de][tiroides con infilracion de la medulaosea y del sistemanerviosa central]. Med. Clin., 2001; 116: 9: 357, 358.][8. Thieblemont C., Mayer A., Dumontet C. et al. Pervichnaya limfoma shchitovidnoy zhelezy yavlyayetsya geterogennym zabolevaniyem [Primary thyroid lymphoma is a heterogeneous disease]. J. Clin. Endocrinol. Metab., 2002; 87(1): 105.]