Journal of Experimental and Clinical SurgeryJournal of Experimental and Clinical Surgery2070-478X2409-143XVoronezh State Medical University59210.18499/2070-478X-2011-4-3-557-560UnknownMorpho-functional alterations of dorsal root ganglion neurons on the soft tissue woundssns7250@rambler.rusurgery-v@yandex.rusns7250@rambler.ru516753@gmail.comfetisovbiol@bk.ru24092011435575600805201608052016Copyright © 2011, ., ., ., ., .2011Morfo-functional characteristics of dorsal root ganglion neurons allow to estimate in dynamics occurring in initial department<br />of refl ex arch of nervous system processes. Neurons react to wounds of soft tissue with complex of the adaptive reactions<br />shows us populations of cells with a various functional condition: cells with reversible changes and cells with destructive<br />changes. At application platelet-rich blood plasma for treatment of wounds, in comparison with a natural current of process,<br />are observed quantitative changes of neurons with a various functional condition. The quantity of cells with destructive<br />changes decreases in all terms of research, and the quantity of cells with reversible changes increases in the beginning of<br />experiment and decreases in late terms. Such dynamics is refl ection of activation of processes of healing at application of<br />platelet-rich blood plasma for wound treatment.dorsal root ganglionneuronsmorphologywoundsenriched by platelets blood plasmaспинномозговые узлынейроныморфологияраныобогащенная тромбоцитами плазма крови[1. Bulynin V.I., Glukhov A.A., Moshurov I.P. Lechenie ran.][Voronezh: Izd-vo VGU, 1998. 248.][2. Galabov G.P. Morfologicheskii i gistokhimicheskii][analiz kletok spinnogo mozga i spinal'nykh gangliev][v usloviiakh razlichnykh travm i regeneratsii periferi-][cheskikh nervov. Struktura i funktsiia nervnoi sistemy.][M.: Meditsina 1962; 65-73.][3. Glukhov A.A., Ostroushko A.P., Semenov S.N., Alekseeva][N.T., Bugrimov D.Iu. Strukturno-funktsional'nye oso-][bennosti zazhivleniia asepticheskikh ran miagkikh tkanei][pri ispol'zovanii obogashchennoi trombotsitami plaz-][my krovi. Vestnik eksperimental'noi i klinicheskoi][khirurgii 2010; 3: 3: 210-213.][4. Grigor'eva T.A. O prichinakh troficheskikh rasstroistv][v lishennykh chuvstvitel'nosti uchastkakh organizma.][Dokl. AN SSSR. 1951; 60: 2: 389-390.][5. Ermolin I.L. Morfologiia spinnomozgovogo uzla v][norme i v usloviiakh deafferentatsii u vzrosloi krysy:][Avtoref. dis. …dokt. biol. nauk: Nizhnii Novgorod,][2006; 29.][6. Zhabotinskii Iu.M. Normal'naia i patologicheskaia][morfologiia neirona. L.: Meditsina 1965; 193.][7. Kriukov K.I. Morfologicheskie izmeneniia neironov][Gasserova uzla pri kompressionnoi travme litsevogo][otdela golovy krysy (eksperimental'noe issledova-][nie): Avtoref. dis. …kand. med. nauk: Vladivostok][2008; 19.][8. Lioznera L.D. Novoe v uchenii o regeneratsii. M.: Me-][ditsina 1977; 358.][9. Shade Dzh., Ford D. Osnovy nevrologii. M.: Mir 1976;][350.][10. Iarygin N.E., Iarygin V.N. Patologicheskie i prisposo-][bitel'nye izmeneniia neirona. M.: Meditsina 1973; 191.][11. Timothy E. Foster, Brian L. Puskas, Bert R. Mandelbaum][et al. Platelet-Rich Plasma: From basic science to clinical][application. The Am J Sports Med. 2009; 37: 2249-2251.]