Journal of Experimental and Clinical SurgeryJournal of Experimental and Clinical Surgery2070-478X2409-143XVoronezh State Medical University68110.18499/2070-478X-2010-3-2-123-128UnknownTreatment of intra-abdominal hypertension in patients with diffuse peritonitis, complicated by the severe abdominal sepsis.author@vestnik-surgery.com.author@vestnik-surgery.com.author@vestnik-surgery.com.author@vestnik-surgery.com.author@vestnik-surgery.com.24062010321231281805201618052016Copyright © 2010, ., ., ., ., .2010The analysis of the results of diagnosis and treatment of 60 patients with the diffuse purulent peritonitis. The first (control) group consist of 34 patients treated by programmed sanitations of the abdominal cavity with application by common method without intra-abdominal pressure using to close laparostomy, which was closed by the “zipper” method. The second (study) group included 26 patients, for which there were used a large-cellular mesh polypropylene endoprosthesis to close the defects of abdominal wall. At each programmed sanitation the prosthesis was dissected longitudinally along the entire length and stapled so that the level of intra-abdominal pressure did not exceed 15 mm Hg. In the nearest post-operative period in patients of the second group the indicators of endotoxicosis were 1,3 times lower, the motility and peristalsis of the intestines was 2,1 times higher than in patients of the first group, which led to the decrease of post-operative lethality in 1,3 timesdiffused peritonitisabdominal compartment syndromelaparostomypolypropylene endoprosthesis.распространенный перитонитинтраабдоминальная гипертензиялапаростомияполипропиленовый эндопротез[1. Gel'fand B.R., Protsenko D.N., Ignatenko O.V., Iaroshets-][kii A.I. Sindrom intraabdominal'noi gipertenzii.][Consilium medicum 2005; 7: 1: 20-25.][2. Gostishchev V.K., Sazhin V.P., Avdovenko A.P. Peritonit.][M.: GO-TAR i MED, 2002; 224.][3. Eriukhin I.A., Shliapnikov S.A. Khirurgicheskii sepsis][(diskussionnye aspekty problemy). Khirurgiia 2000; 3:][44-46.][4. Savel'ev V.S., Gel'fand B.R., Filimonov M.I. Perito-][nit. - M.: Litera, 2006; 206.][5. Sazhin V.P., Avdovenko A.P., Iurishev V.A. Sovremen-][nye tendentsii khirurgicheskogo lecheniia peritonita.][Khirurgiia 2007; 11: 36-39.][6. Svetukhin A.M., Zviagin A.K., Slepnev S.Iu. Sistema ob"-][ektivnoi otsenki tiazhesti sostoianiia bol'nykh. Chast' I.][Khirurgiia 2002; 9: 51-57.][7. Fedorov V.D., Gostishchev V.K., Ermolov A.S., Bagnitskaia][T.N. Sovremennye predstavleniia o klassifikatsii pe-][ritonita i sistemakh otsenki tiazhesti bol'nykh. Khirur-][giia 2000; 4: 58-62.][8. Cheatham M.L. Intra-abdominal hypertension and][abdominal compartment syndrome. New Horizons: Sci.][and Pract. Acute Med. 1999; 7: 96-115.][9. Eddy V., Nunn C., Morris J. Abdominal compartment][syndrome. The Nashville experience. Surg. Clin. North][Am. 1997; 77: 801-812.][10. Malbrain M.L. Abdominal pressure in the critically ill.][Curr. Opinion Crit. Care 2000; 6: 17-29.][11. Sigel B., Golub R.M., Loiacono L.A. et al. Technique][of ultrasonic detection and mapping of abdominal wall][adhesions. Surg. Endosc 1991; 5: 161-165.][12. Ware J.E., Sherbourne C.D. The MOS 36-item short form][health survey (SF-36): conceptual framework and item][selection. Med. Care 1992; 30: 473-483.]