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Analysed outcomes of surgical treatment of patients with metastatic lesions of the cervical spine
- Authors: Tatarincev A.P.1, Ptashnikov D.A.1,2, Mytyga P.G.1
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Affiliations:
- Russian Scientific Research Institute of Traumatology and Orthopedicsnamed after R.R. Vreden
- Saint-Petersburg Clinical Hospital of the Russian Academy of Sciences
- Issue: Vol 18, No 4 (2025)
- Pages: 265-274
- Section: Original articles
- URL: https://vestnik-surgery.com/journal/article/view/1866
- DOI: https://doi.org/10.18499/2070-478X-2025-18-4-265-274
- ID: 1866
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Abstract
Backgraund. Metastatic lesions of the cervical vertebrae occur, on average, in 15% of patients with metastases to the spine. Compression of the spinal cord by tumor masses in this part of the spine leads to rapid progression of neurological deficits, decreased quality of life, and death. Currently, no single option of surgical treatment for this cohort of patients has been proposed.
The aim of the study was to evaluate the results of surgical treatment of patients with metastatic lesions of the cervical vertebrae.
Materials and methods. An ambispective single-center study included patients who underwent surgical treatment for metastatic lesions of the cervical spine between 2010 and 2023. The study included patients over 18 years of age who were admitted to surgical treatment based on their somatic status. Patients with vertebral lesions caused by a primary tumor or lymphoproliferative disease, and patients with severe neurological deficit were excluded. The traumatic nature of the surgery, the dynamics of pain syndrome and neurological symptoms, and changes in the patient's functional status 1 and 3 months after surgery, as well as at various points during life after surgical treatment, were assessed. The study involved 80 patients who were divided into groups depending on the method of surgical treatment: in group "A" - orthotics with biopsy, ablation, vertebroplasty of the affected vertebrae in various combinations were performed, in groups B (retrospective) and C (prospective) - decompressive stabilizing intervention without metastasectomy, in groups D (retrospective) and E (prospective) - metastasectomy, decompression of neural structures and stabilization of the spine.
Results. The results of the study showed regression of neurological symptoms and pain syndrome in all operated patients throughout the entire observation period. Survival of patients in prospective groups was higher than in retrospective ones, especially with metastasectomy.
Conclusions. Surgical treatment of metastatic lesions of the spine leads to regression of existing neurological symptoms and pain control, regardless of the chosen surgical treatment option. The survival rate of patients with metastasectomy within 5 years after surgical treatment is higher than among patients in other groups.
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About the authors
Alexandr P. Tatarincev
Russian Scientific Research Institute of Traumatology and Orthopedicsnamed after R.R. Vreden
Author for correspondence.
Email: nhovreden@rambler.ru
ORCID iD: 0000-0003-3375-7707
SPIN-code: 1098-0211
Neurosurgeon
Russian Federation, Saint-PetersburgDmitry A. Ptashnikov
Russian Scientific Research Institute of Traumatology and Orthopedicsnamed after R.R. Vreden; Saint-Petersburg Clinical Hospital of the Russian Academy of Sciences
Email: drptashnikov@yandex.ru
ORCID iD: 0000-0001-5765-3158
SPIN-code: 7678-6542
M.D., professor, head doctor
Russian Federation, Saint-Petersburg; Saint-PetersburgPavel G. Mytyga
Russian Scientific Research Institute of Traumatology and Orthopedicsnamed after R.R. Vreden
Email: paveji.official@gmail.com
ORCID iD: 0000-0002-4386-9780
SPIN-code: 6853-3113
traumatologist orthopedist
Russian Federation, Saint-PetersburgReferences
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