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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="other" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Journal of Experimental and Clinical Surgery</journal-id><journal-title-group><journal-title xml:lang="en">Journal of Experimental and Clinical Surgery</journal-title><trans-title-group xml:lang="ru"><trans-title>Вестник экспериментальной и клинической хирургии</trans-title></trans-title-group></journal-title-group><issn publication-format="print">2070-478X</issn><issn publication-format="electronic">2409-143X</issn><publisher><publisher-name xml:lang="en">Voronezh State Medical University named after N.N. Burdenko</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">100</article-id><article-id pub-id-type="doi">10.18499/2070-478X-2014-7-2-165-176</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Original articles</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Оригинальные статьи</subject></subj-group><subj-group subj-group-type="article-type"><subject>Unknown</subject></subj-group></article-categories><title-group><article-title xml:lang="en">New Methods of Treatment of the Diffused Peritonitis</article-title><trans-title-group xml:lang="ru"><trans-title>Новые способы лечения распространенного перитонита</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name><surname>Суховатых</surname><given-names>Б.С.</given-names></name><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>MD, Professor, head of General Surgery Department. Address: 305041 Kursk, Karl Marx str., 3. Kursk state medical university, Department of General Surgery</p></bio><bio xml:lang="ru"><p>д.м.н., проф., зав. кафедрой общей хирургии Курского государственного медицинского университета</p></bio><email>author@vestnik-surgery.com</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name><surname>Блинков</surname><given-names>Ю.Ю.</given-names></name><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>MD, Professor, head of General Surgery Department. Address: 305041 Kursk, Karl Marx str., 3. Kursk state medical university, Department of General Surgery</p></bio><bio xml:lang="ru"><p>д.м.н., доц. кафедры общей хирургии Курского государственного медицинского университета</p></bio><email>author@vestnik-surgery.com</email><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">Kursk State Medical University, 3 K.Marks Str., Kursk, 305041, Russian Federation</institution></aff><aff><institution xml:lang="ru">Курский государственный медицинский университет, ул. К.Маркса, д. 3, Курск, 305041, Российская Федерация</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2014-06-24" publication-format="electronic"><day>24</day><month>06</month><year>2014</year></pub-date><volume>7</volume><issue>2</issue><issue-title xml:lang="ru"/><fpage>165</fpage><lpage>176</lpage><history><date date-type="received" iso-8601-date="2016-04-26"><day>26</day><month>04</month><year>2016</year></date><date date-type="accepted" iso-8601-date="2016-04-26"><day>26</day><month>04</month><year>2016</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2014, ., .</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2014, Суховатых Б., Блинков Ю.</copyright-statement><copyright-year>2014</copyright-year><copyright-holder xml:lang="en">., .</copyright-holder><copyright-holder xml:lang="ru">Суховатых Б., Блинков Ю.</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">http://creativecommons.org/licenses/by-nc-nd/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://vestnik-surgery.com/journal/article/view/100">https://vestnik-surgery.com/journal/article/view/100</self-uri><abstract xml:lang="en"><p>Despite the achievements of the modern medicine, diffused peritonitis until the present time remains the urgent problem in the emergent abdominal surgery. According to the data of the leading Russian and foreign clinics, mortality rate in this pathology in the last decades has not showed any reduction tendency and varied in the range of minimum 20-30%, achieving at maximum 50-70%. The article presents analytical review of new approaches to the treatment of the diffused peritonitis. The authors describe in detail their own developed three methods of treatment of peritonitis and indications for their application. In traditional (semi-closed method of treatment) sanitation of the abdominal cavity was conducted with the use of immobilized forms of sodium hypochlorite in the gel of carboxymetilcellulose. Deponent of the antiseptic prolongs its bactericidal action, while the gel of carboxymetilcellulose prevents the gluing of the organs’ surfaces , by which reduces the severity of adhesive process. In surgical-laporoscopic method of treatment video-endoscopic sanitations of the abdominal cavity were done by pulsating irrigation of antiseptic. To close the defects of the abdominal cavity in semi-open method of treatment there was used large-net endoprothesis made from polypropylene. Between the edges of the wound there was left diastases, at which intra-abdominal pressure was below 15 mm. of mercury column. For selection of the appropriate method of treatment there was used the original scale of quantitative evaluation of factors, influencing lethality rate of patients. It was proved that semi-closed method of treatment is reasonable to use in patients without signs of the abdominal sepsis, while programmed video-laparoscopic sanitations should be used in cases of abdominal sepsis without poly-organic dysfunction and intra-abdominal pressure below 20 mm. of mercury column, programmed surgical sanitations are indicated for patients with severe abdominal sepsis with poly-organic insufficiency and abdominal hypertension above 20 mm of mercury column. Introduction of new methods of treatment to practice enabled to decrease the number of postoperative complications by 10% and lethality – by 8,2%</p></abstract><trans-abstract xml:lang="ru"><p>Несмотря на достижения современной медицины, распространенный перитонит до настоящего времени остается актуальной проблемой в неотложной абдоминальной хирургии. По данным ведущих отечественных и зарубежных клиник летальность при данной патологии за последние десятилетия не имеет тенденции к снижению и колеблется от 20-30% до 50-70%. В статье представлен аналитический обзор новых подходов к лечению распространенного перитонита. Подробно описаны разработанные авторами три новых способа лечения перитонита и показания к их применению. При традиционном (полузакрытом способе лечения) санация брюшной полости проводилась при помощи иммобилизированных форм гипохлорита натрия в геле карбоксиметилцеллюлозы. Депонирование антисептика пролонгирует его бактерицидное действие, а гели карбоксиметилцеллюлозы препятствуют слипанию поверхностей органов и, тем самым, снижают выраженность спаечного процесса. При хирургическо-эндоскопическом способе лечения видеоэндоскопические санации брюшной полости проводились при помощи пульсирующей струи антисептика, для создания которой использовался ирригатор. Для закрытия дефекта брюшной стенки при полуоткрытом способе лечения применялся крупноячеистый сетчатый полипропиленовый эндопротез, при этом между краями раны оставлялся диастаз, при котором внутрибрюшное давление оставалось менее 15 мм рт. ст. Для выбора того или иного способа лечения использовалась оригинальная шкала количеств�нной оценки факторов, влияющих на летальность больных. Установлено, что полузакрытый способ лечения целесообразно применять у больных без проявлений абдоминального сепсиса и внутрибрюшной гипертензии, программированные видеоэндоскопические санации – при абдоминальном сепсисе без полиорганной дисфункции и внутрибрюшной гипертензии до 20 мм рт. ст., программированные хирургические санации показаны больным с тяжелым абдоминальным сепсисом с полиорганной недостаточностью и абдоминальной гипертензией свыше 20 мм рт. ст. Внедрение новых способов лечения позволило снизить количество послеоперационных осложнений на 10%, а летальность на 8,2%.</p></trans-abstract><kwd-group xml:lang="en"><kwd>diffused peritonitis</kwd><kwd>immobilized forms of sodium hypochlorite</kwd><kwd>methods of surgical treatment: semi-closed</kwd><kwd>surgicallaparoscopic</kwd><kwd>semi-opened</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>распространенный перитонит</kwd><kwd>иммобилизированные формы гипохлорита натрия</kwd><kwd>способы хирургического лечения: полузакрытый</kwd><kwd>хирургическо-эндоскопический</kwd><kwd>полуоткрытый</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>1. Askerkhanov G. R. Zaprogrammirovannaya relaparotomiya pri peritonite. Hirurgiya, [Programmed relaparotomy in peritonitis. Surgery,] 2000; 8: 20-23.</mixed-citation></ref><ref id="B2"><label>2.</label><mixed-citation>2. Bolotnikov, A. I. 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