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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="other" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Journal of Experimental and Clinical Surgery</journal-id><journal-title-group><journal-title xml:lang="en">Journal of Experimental and Clinical Surgery</journal-title><trans-title-group xml:lang="ru"><trans-title>Вестник экспериментальной и клинической хирургии</trans-title></trans-title-group></journal-title-group><issn publication-format="print">2070-478X</issn><issn publication-format="electronic">2409-143X</issn><publisher><publisher-name xml:lang="en">Voronezh State Medical University named after N.N. Burdenko</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">115</article-id><article-id pub-id-type="doi">10.18499/2070-478X-2012-5-4-639-643</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Original articles</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Оригинальные статьи</subject></subj-group><subj-group subj-group-type="article-type"><subject>Unknown</subject></subj-group></article-categories><title-group><article-title xml:lang="en">Clinico-pathogenetic substantiation antimycotic use of funds in complex treatment of patients with diabetic foot syndrome</article-title><trans-title-group xml:lang="ru"><trans-title>Клинико-патогенетическое обоснование применения антимикотических средств в комплексном лечении пациентов с синдромом диабетической стопы</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name><surname>Глухов</surname><given-names>А.А.</given-names></name><address><country country="RU">Russian Federation</country></address><bio xml:lang="ru"><p>Глухов Александр Анатольевич – д.м.н., проф., зав. кафедрой общей хирургии, директор НИИ хирур- гической инфекции Воронежской государственной медицинской академии им. Н.Н.Бурденко</p></bio><email>surgery-v@ya.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name><surname>Зуйкова</surname><given-names>А.А.</given-names></name><address><country country="RU">Russian Federation</country></address><bio xml:lang="ru"><p>Зуйкова Анна Александровна – д.м.н., проф., зав. кафедрой семейной медицины Воронеж- ской государственной медицинской академии им. Н.Н.Бурденко</p></bio><email>ovpzuikova@rambler.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name><surname>Петрова</surname><given-names>Т.Н.</given-names></name><address><country country="RU">Russian Federation</country></address><bio xml:lang="ru"><p>Петрова Татьяна Николаевна – к.м.н., доц. кафедры семейной медицины Воронежской государствен- ной медицинской академии им. Н.Н.Бурденко</p></bio><email>LUNAR200@yandex.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name><surname>Андреев</surname><given-names>А.А.</given-names></name><address><country country="RU">Russian Federation</country></address><bio xml:lang="ru"><p>Андреев Александр Алексеевич – д.м.н., доц. кафе- дры общей хирургии Воронежской государствен- ной медицинской академии им. Н.Н.Бурденко</p></bio><email>sugery@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name><surname>Остроушко</surname><given-names>А.П.</given-names></name><address><country country="RU">Russian Federation</country></address><bio xml:lang="ru"><p>Остроушко Антон Петрович – к.м.н., ассистент кафедры общей хирургии, заместитель дирек- тора НИИ хирургической инфекции Воронеж- ской государственной медицинской академии им. Н.Н.Бурденко по инновационным проектам</p></bio><email>antonostroushko@ya.ru</email><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff id="aff1"><institution>Воронежская государственная медицинская академия им. Н.Н.Бурденко</institution></aff><pub-date date-type="pub" iso-8601-date="2012-12-24" publication-format="electronic"><day>24</day><month>12</month><year>2012</year></pub-date><volume>5</volume><issue>4</issue><issue-title xml:lang="ru"/><fpage>639</fpage><lpage>643</lpage><history><date date-type="received" iso-8601-date="2016-04-27"><day>27</day><month>04</month><year>2016</year></date><date date-type="accepted" iso-8601-date="2016-04-27"><day>27</day><month>04</month><year>2016</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2012, Voronezh N.N. Burdenko State Medical University</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2012, ФГБОУ ВО ВГМУ им. Н.Н. Бурденко Минздрава России</copyright-statement><copyright-year>2012</copyright-year><copyright-holder xml:lang="en">Voronezh N.N. Burdenko State Medical University</copyright-holder><copyright-holder xml:lang="ru">ФГБОУ ВО ВГМУ им. Н.Н. Бурденко Минздрава России</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://vestnik-surgery.com/journal/about/editorialPolicies</ali:license_ref></license></permissions><self-uri xlink:href="https://vestnik-surgery.com/journal/article/view/115">https://vestnik-surgery.com/journal/article/view/115</self-uri><abstract xml:lang="en"><p>Patients with diabetes, especially diabetic foot syndrome, are at high risk of mycotic infections of feet. The presence of fungal infections is much heavier during the diabetic foot, as an additional risk factor for complicated forms and more protracted healing of wounds sanitized. For this reason, the appointment of antibiotic therapy in all patients with foot ulcer and diabetes mellitus should be based on the results of bacteriological seeding with the definition of fungal infection. In the presence of mycotic contamination of the wound antibiotic therapy is useful to combine c antifungal agents.</p></abstract><trans-abstract xml:lang="ru"><p>Больных сахарным диабетом, особенно с синдромом диабетической стопы, относят к группе высокого риска раз- вития микотической инфекции стоп. Наличие грибкового поражения значительно утяжеляет течение синдрома диабетической стопы, являясь дополнительным фактором риска развития осложненных форм и более затяжного характера заживления санированных ран. Исходя из этого, назначение антибактериальной терапии всем больным с язвенными дефектами стоп на фоне сахарного диабета должно базироваться на результатах бактериологического посева с определением грибковой инфекции. При наличии микотической обсемененности антибиотикотерапию це- лесообразно комбинировать c назначением противогрибковых препаратов.</p></trans-abstract><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>1. Ametov A.S., Shaparenko M.V. Diabeticheskaia stopa i</mixed-citation></ref><ref id="B2"><label>2.</label><mixed-citation>gribkovye porazheniia nizhnikh konechnostei.[Diabetic foot and fungal damages of the lower extremities.]. Vestnik</mixed-citation></ref><ref id="B3"><label>3.</label><mixed-citation>poslediplomnogo meditsinskogo obrazovaniia 2004; 2:</mixed-citation></ref><ref id="B4"><label>4.</label><mixed-citation>35-39.</mixed-citation></ref><ref id="B5"><label>5.</label><mixed-citation>2. Batkaev E.A. Kompleksnoe lechenie mikozov u bol'nykh</mixed-citation></ref><ref id="B6"><label>6.</label><mixed-citation>sindromom diabeticheskoi stopy.[Complex treatment of mycoses at patients with a syndrome of diabetic foot.]. 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