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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="other" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Journal of Experimental and Clinical Surgery</journal-id><journal-title-group><journal-title xml:lang="en">Journal of Experimental and Clinical Surgery</journal-title><trans-title-group xml:lang="ru"><trans-title>Вестник экспериментальной и клинической хирургии</trans-title></trans-title-group></journal-title-group><issn publication-format="print">2070-478X</issn><issn publication-format="electronic">2409-143X</issn><publisher><publisher-name xml:lang="en">Voronezh State Medical University named after N.N. Burdenko</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">135</article-id><article-id pub-id-type="doi">10.18499/2070-478X-2012-5-2-304-309</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Original articles</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Оригинальные статьи</subject></subj-group><subj-group subj-group-type="article-type"><subject>Unknown</subject></subj-group></article-categories><title-group><article-title xml:lang="en">Clinico-morfologic signs of the complications of the ulcer disease with chronic duodenal obstruction</article-title><trans-title-group xml:lang="ru"><trans-title>Клинико-морфологические особенности осложнений язвенной болезни при хронических нарушениях дуоденальной проходимости</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name><surname>Назаренко</surname><given-names>П.М.</given-names></name><bio xml:lang="ru"><p>д.м.н., проф., зав. кафедрой хирургии №2 Курского государственногомедицинского университета; e-mail: TASS@list.ru</p></bio><email>author@vestnik-surgery.com</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name><surname>Самгина</surname><given-names>T.A</given-names></name><bio xml:lang="ru"><p>к.м.н., асс. ка-федры хирургии №2 Курского государственногомедицинского университета; e-mail: TASS@list.ru</p></bio><email>author@vestnik-surgery.com</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name><surname>Биличенко</surname><given-names>В.Б.</given-names></name><bio xml:lang="ru"><p>медицинского университета; e-mail: TASS@list.ru</p></bio><email>author@vestnik-surgery.com</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name><surname>Назаренко</surname><given-names>Д.П.</given-names></name><bio xml:lang="ru"><p>д.м.н, проф. кафе-дры хирургии №2 Курского государственного ме-дицинского университета; e-mail: TASS@list.ru</p></bio><email>author@vestnik-surgery.com</email><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en"></institution></aff><aff><institution xml:lang="ru">Курский государственный медицинский университет</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2012-06-24" publication-format="electronic"><day>24</day><month>06</month><year>2012</year></pub-date><volume>5</volume><issue>2</issue><issue-title xml:lang="ru"/><fpage>304</fpage><lpage>309</lpage><history><date date-type="received" iso-8601-date="2016-04-27"><day>27</day><month>04</month><year>2016</year></date><date date-type="accepted" iso-8601-date="2016-04-27"><day>27</day><month>04</month><year>2016</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2012, ., ., ., .</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2012, Назаренко П., Самгина T., Биличенко В., Назаренко Д.</copyright-statement><copyright-year>2012</copyright-year><copyright-holder xml:lang="en">., ., ., .</copyright-holder><copyright-holder xml:lang="ru">Назаренко П., Самгина T., Биличенко В., Назаренко Д.</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">http://creativecommons.org/licenses/by-nc-nd/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://vestnik-surgery.com/journal/article/view/135">https://vestnik-surgery.com/journal/article/view/135</self-uri><abstract xml:lang="en"><p>The results of the treatment of 118 patients with chronic complications of the ulcer disease were studied. 1 group- 60 patientsoperated with chronic complications of the ulcer disease without correction of the motility of the duodenum. 2 group – 58 patients operated with chronic complications of the ulcer disease and correction of the chronic duodenal obstruction was done. Morphologic investigation of the stomach and duodenal mucous membrane showed that after conservative or surgical correction of the chronic duodenal obstruction in patients with chronic complications of the ulcer disease signs of disturbed secretion, protection function and endocrinopathy were removed.</p></abstract><trans-abstract xml:lang="ru"><p>Изучены результаты обследования и лечения118 больных с хроническими осложнениями язвенной болезни. В кон-трольную группу вошло60 больных, которым хирургическое лечение осложненных форм язвенной болезни прово-дилось без коррекции моторно-эвакуаторной функции двенадцатиперстной кишки(ДПК). В основную группу вошло58 больных, которым хирургическое лечение язвенной болезни, в показанных случаях, проводилось с коррекциейхронических нарушений дуоденальной проходимости(ХНДП). При гистологическом изучении биопсийного и опе-рационного материала до лечения, направленного на коррекцию ХНДП, выявлен ряд специфических особенностей, свидетельствующих о рефлюксной природе гастрита, нарушение секреторной функции слизистой оболочки желуд-ка, снижение протективных свойств эпителия двенадцатиперстной кишки и снижение функциональной активностиэндокринных клеток.</p></trans-abstract><kwd-group xml:lang="en"><kwd>chronic complications of the ulcer disease</kwd><kwd>the chronic duodenal obstruction</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>хронические осложнения язвенной болезни желудка и двенадцатиперстной кишки</kwd><kwd>хронические наруше- ния дуоденальной проходимости</kwd><kwd>патоморфология слизистой оболочки желудка и двенадцатиперстной кишки</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>1. Bilichenko V.B. 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