Journal of Experimental and Clinical Surgery

Вестник экспериментальной и клинической хирургии

2070-478X2409-143X

Voronezh State Medical University named after N.N. Burdenko

143

10.18499/2070-478X-2012-5-2-347-353

Original articles

Оригинальные статьи

Unknown

The immune oriented nutrition support for patients with severe acute nontraumatic intracranial hemorrhage

Иммуноориентированная нутритивная поддержка у пациентов с тяжелым нетравматическим внутримозговым кровоизлиянием

Струк

Ю.В.

д.м.н., проф., зав. ка-федрой анестезиологии и реаниматологии ИДМОВоронежской государственной медицинской акаде-мии им. Н.Н.Бурденко; e-mail: u_struk@mail.ru

author@vestnik-surgery.comХомяков

С.В.

врач анестезио-лог-реаниматолог, заведующий отделением анесте-зиологии-реанимации №4 Белгородской областнойклинической больницы Святителя Иоасафа; e-mail: aro.bokb@mail.ru

author@vestnik-surgery.com

Воронежская государственная медицинской академии им. Н.Н.Бурденко Белгородская областная клиническая больница Святителя Иоасафа

24062012

3473532704201627042016

2012

., .

Струк Ю., Хомяков С.

http://creativecommons.org/licenses/by-nc-nd/4.0

https://vestnik-surgery.com/journal/article/view/143

The actual work presents the results of using various programs of nutrition support for patients with severe nontraumatic intracranial hemorrhage. The huge reduction of both cellular and humoral immunity is established in the first day of the onset of the disease. The authors assess the impact of the combined enteral-parenteral nutritive support with dipeptide alanine-glutamine on immune rates and severity of nutrition deficiency. The work deals with the comparative characteristics of complications of these nutrition programs. It is established, that application of alanine-glutamine in complex intensive therapy reduces the frequency of pneumonia, delays pneumonia development, reduces the duration of mechanical ventilation and the time of ICU stay.

В работе представлены результаты применения различных программ нутритивной поддержки у пациентов с тя-желым нетравматическим внутримозговым кровоизлиянием. Установлено выраженное снижение показателей какклеточного, так и гуморального звеньев иммунитета в первые сутки от начала заболевания. Произведена оценкавлияния программы комбинированной энтерально-парентеральной нутритивной поддержки, включающей введе-ние дипептида аланин-глютамина, на показатели иммунитета, а также на тяжесть нутритивной недостаточности. Представлена сравнительная характеристика осложнений при проведении рассматриваемых нутритивных про-грамм. Установлено, что применение аланин-глюмина в комплексной интенсивной терапии позволяет уменьшитьчастоту развития пневмонии, отодвинуть сроки ее развития, уменьшить длительность ИВЛ, сроки лечения пациен-та в отделении реанимации.

intracranial hemorrhagenutrition supportnutrition insuffi ciencyenteral nutritionparenteral nutritionimmune system

внутричерепное кровоизлияниенутритивная поддержканутритивная недостаточностьэнтеральное питаниепарентеральное питаниеиммунная система

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