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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="research-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Journal of Experimental and Clinical Surgery</journal-id><journal-title-group><journal-title xml:lang="en">Journal of Experimental and Clinical Surgery</journal-title><trans-title-group xml:lang="ru"><trans-title>Вестник экспериментальной и клинической хирургии</trans-title></trans-title-group></journal-title-group><issn publication-format="print">2070-478X</issn><issn publication-format="electronic">2409-143X</issn><publisher><publisher-name xml:lang="en">Voronezh State Medical University named after N.N. Burdenko</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">1435</article-id><article-id pub-id-type="doi">10.18499/2070-478X-2021-14-1-10-18</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Original articles</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Оригинальные статьи</subject></subj-group><subj-group subj-group-type="article-type"><subject>Research Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">Concomitant Liver Disease: Echinococcosis and Aspergillosis</article-title><trans-title-group xml:lang="ru"><trans-title>Сочетанное поражение печени: эхинококкоз и аспергиллез</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-6450-1419</contrib-id><name-alternatives><name xml:lang="en"><surname>Usmonov</surname><given-names>Umid Donakuzievich</given-names></name><name xml:lang="ru"><surname>Усмонов</surname><given-names>Умид Донакузиевич</given-names></name></name-alternatives><address><country country="UZ">Uzbekistan</country></address><bio xml:lang="en"><p>Ph.D., associate professor of Surgery and Urology Department</p></bio><bio xml:lang="ru"><p>доцент кафедры хирургии и урологии</p></bio><email>udusmonov@gmail.com</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Nishonov</surname><given-names>Fozil Nishonovich</given-names></name><name xml:lang="ru"><surname>Нишонов</surname><given-names>Фозил Нишонович</given-names></name></name-alternatives><address><country country="UZ">Uzbekistan</country></address><bio xml:lang="en"><p>M.D., professor, head of Surgery and Urology Department of Andijan State Medical Institute</p></bio><bio xml:lang="ru"><p>д.м.н., профессор, заведующий кафедрой хирургии и урологии Андижанского государственного медицинского института</p></bio><email>usmonovud@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Otakuziev</surname><given-names>Akhmadillo Zokirovich</given-names></name><name xml:lang="ru"><surname>Отакузиев</surname><given-names>Ахмадилло Зокирович</given-names></name></name-alternatives><address><country country="UZ">Uzbekistan</country></address><bio xml:lang="en"><p>Ph.D., associate professor of Surgery and Urology Department of Andijan State Medical Institute</p></bio><bio xml:lang="ru"><p>к.м.н., доцент кафедры хирургии и урологии Андижанского государственного медицинского института</p></bio><email>malik4449@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Stepanova</surname><given-names>Yulia Alexandrovna</given-names></name><name xml:lang="ru"><surname>Степанова</surname><given-names>Юлия Александровна</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>M.D., professor, Academic Secretary of A.V. Vishnevsky National Medical Research Center of Surgery</p></bio><bio xml:lang="ru"><p>д.м.н., профессор, Ученый секретарь ФГБУ «Национальный медицинский исследовательский центр хирургии им. А.В. Вишневского» Минздрава России</p></bio><email>stepanovaua@mail.ru</email><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Vishnevsky</surname><given-names>Vladimir Aleksandrovich</given-names></name><name xml:lang="ru"><surname>Вишневский</surname><given-names>Владимир Александрович</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>M.D., professor, Advisor of Surgery to the Director of A.V. Vishnevsky National Medical Research Center of Surgery</p></bio><bio xml:lang="ru"><p>д.м.н., профессор, Советник директора по хирургии ФГБУ «Национальный медицинский исследовательский центр хирургии им. А.В. Вишневского» Минздрава России</p></bio><email>vishnevskogo@ixv.ru</email><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Botiraliev</surname><given-names>Aziz Shukurzhonovich</given-names></name><name xml:lang="ru"><surname>Ботиралиев</surname><given-names>Азиз Шукуржонович</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>applicant for the Ph.D. degree in the specialty "surgery " of A.V. Vishnevsky National Medical Research Center of Surgery</p></bio><bio xml:lang="ru"><p>соискатель ученой степени кандидата медицинских наук по специальности «хирургия» ФГБУ «Национальный медицинский исследовательский центр хирургии им. А.В. Вишневского» Минздрава России</p></bio><email>azizhanshukur@mail.ru</email><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Abdulkhaeva</surname><given-names>Barnokhon Khabibilo Kizi</given-names></name><name xml:lang="ru"><surname>Абдулхаева</surname><given-names>Барнохон Хабибило кизи</given-names></name></name-alternatives><address><country country="UZ">Uzbekistan</country></address><bio xml:lang="en"><p>Master of the Department of Surgery and Urology, Andijan State Medical Institute</p></bio><bio xml:lang="ru"><p>магистр кафедры хирургии и урологии Андижанского государственного медицинского института</p></bio><email>bazno_a@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">Andijan State Medical Institute</institution></aff><aff><institution xml:lang="ru">Андижанский государственный медицинский институт</institution></aff></aff-alternatives><aff-alternatives id="aff2"><aff><institution xml:lang="en">A.V. Vishnevsky National Medical Research Center of Surgery</institution></aff><aff><institution xml:lang="ru">Национальный медицинский исследовательский центр хирургии им. А.В. Вишневского</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2021-03-26" publication-format="electronic"><day>26</day><month>03</month><year>2021</year></pub-date><volume>14</volume><issue>1</issue><issue-title xml:lang="ru"/><fpage>10</fpage><lpage>18</lpage><history><date date-type="received" iso-8601-date="2020-06-20"><day>20</day><month>06</month><year>2020</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2021, Voronezh N.N. Burdenko State Medical University</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2021, ФГБОУ ВО ВГМУ им. Н.Н. Бурденко Минздрава России</copyright-statement><copyright-year>2021</copyright-year><copyright-holder xml:lang="en">Voronezh N.N. Burdenko State Medical University</copyright-holder><copyright-holder xml:lang="ru">ФГБОУ ВО ВГМУ им. Н.Н. Бурденко Минздрава России</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://vestnik-surgery.com/journal/about/editorialPolicies</ali:license_ref></license></permissions><self-uri xlink:href="https://vestnik-surgery.com/journal/article/view/1435">https://vestnik-surgery.com/journal/article/view/1435</self-uri><abstract xml:lang="en"><p>Aspergillosis covers a wide range of diseases caused by the genus Aspergillus fungi. Aspergillus saprophytic mold is widespread in the environment; its spores are easily inhaled. However, despite the fact that most people inhale aspergillus spores daily, aspergillosis develops mainly in immunocompromised individuals (due to illness or during immunosuppressive therapy).the lungs are affected most often, being the portal for the fungus penetration, but the naso-orbital sinus is also involved in the process. There are few reports on extrapulmonary aspergillosis. Even rarer in the literature are publications about the co-infection of a saprophytic fungus and a hydatid cyst. Only single clinical observations of the coexistence of aspergillosis and echinococcosis in the lungs have been described. No literature data are available on the coexistence of these two pathogens in the liver. The authors present a clinical case of a 54-year-old woman with two echinococcal cysts in the liver and Aspergillus revealed in their structure. The co-infection of liver echinococcosis and aspergillosis is extremely rare. Preoperative verification of the presence of local aspergillosis in this case is practically impossible. However, early diagnosis and treatment are vital, preventing possible complications from becoming infected with these two pathogens. Treatment is based on an early morphological diagnosis and the detection of both pathogens.</p></abstract><trans-abstract xml:lang="ru"><p>Аспергиллёз – понятие, охватывающее широкий спектр заболеваний, вызываемых грибками рода Aspergillus. Плесневый сапрофитный грибок Aspergillus широко распространен в окружающей среде, его споры легко вдыхаются. Однако, при том, что большинство людей вдыхают споры аспергилл ежедневно, развивается аспергиллёз преимущественно у иммуноскомпрометированных лиц (вследствие заболевания или на фоне иммуносупрессивной терапии).Чаще всего поражаются легкие, которые являются обычным порталом проникновения грибка, а также назо-орбитальный синус. Сообщений о внелегочном поражении аспергиллезом опубликовано не так много. Ещё реже в литературе встречаются публикации о сосуществовании сапрофитного гриба и гидатидной кисты. Описаны лишь единичные собственные клинические наблюдения сосуществования аспергиллеза и эхинококкоза в легких. Сосуществование этих двух патогенов в печени в доступной литературе мы не встретили.Представлено клиническое наблюдение женщины 54 лет с двумя эхинококковыми кистами в печени, в структуре которых выявили Aspergillus.Сосуществование эхинококкоза и аспергиллеза печени встречается крайне редко. Дооперационная верификация наличия локального аспергиллеза практически невозможна. Однако, ранняя диагностика и лечение в этом случае, имеют жизненно важное значение, предотвращая возможные осложнения от инфицирования этими двумя патогенами. Лечение основано на ранней постановке морфологического диагноза и выявлении обоих патогенов.</p></trans-abstract><kwd-group xml:lang="en"><kwd>liver echinococcosis</kwd><kwd>liver aspergillosis</kwd><kwd>coexistence of pathogens</kwd><kwd>diagnosis</kwd><kwd>treatment</kwd><kwd>verification.</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>эхинококкоз печени</kwd><kwd>аспергиллез печени</kwd><kwd>сосуществование патогенов</kwd><kwd>диагностика</kwd><kwd>лечение</kwd><kwd>верификация.</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Castillo-Minaya KY, Cherre-Fiestas AC, Somocurcio-Peralta JR. Coexistencia de Aspergilosis e Hidatidosis Pulmonar. Reporte de un caso. Rev Peru Med Exp Salud Publica. 2018; 35(4): 689-694. doi: 10.17843/rpmesp.2018.354.3437.</mixed-citation></ref><ref id="B2"><label>2.</label><mixed-citation>Chen S, Pu JL, Yu J, Zhang JM. 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