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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="other" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Journal of Experimental and Clinical Surgery</journal-id><journal-title-group><journal-title xml:lang="en">Journal of Experimental and Clinical Surgery</journal-title><trans-title-group xml:lang="ru"><trans-title>Вестник экспериментальной и клинической хирургии</trans-title></trans-title-group></journal-title-group><issn publication-format="print">2070-478X</issn><issn publication-format="electronic">2409-143X</issn><publisher><publisher-name xml:lang="en">Voronezh State Medical University named after N.N. Burdenko</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">150</article-id><article-id pub-id-type="doi">10.18499/2070-478X-2013-6-2-140-147</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Original articles</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Оригинальные статьи</subject></subj-group><subj-group subj-group-type="article-type"><subject>Unknown</subject></subj-group></article-categories><title-group><article-title xml:lang="en">Acute Severe Pancreatitis Intra and Early Post Open Packing Operation Complications</article-title><trans-title-group xml:lang="ru"><trans-title>Операционные и ранние послеоперационные осложнения «открытых» операций при тяжелом остром панкреатите</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name><surname>Глабай</surname><given-names>В.П</given-names></name><bio xml:lang="en"><p>MD, professor of surgery, Faculty of postgraduate professional training of physicians, sechenov First Moscow state medical university</p></bio><bio xml:lang="ru"><p>д.м.н., проф., зав. кафедрой хирургии ФППоВ Первого Московского государственного медицинского университета им. И.М. Сеченова</p></bio><email>mail@vestnik-surgery.com</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name><surname>Архаров</surname><given-names>А.В</given-names></name><bio xml:lang="en"><p>Phd, assistant in the department of surgery, Faculty of postgraduate professional training of physicians, sechenov First moscow state medical university</p></bio><bio xml:lang="ru"><p>к.м.н., асс. кафедры хирургии ФППоВ Первого Московского государственного медицинского университета им. И.М. Сеченова</p></bio><email>mail@vestnik-surgery.com</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name><surname>Алиев</surname><given-names>А.И</given-names></name><bio xml:lang="en"><p>postgraduate, Chair of surgery, Faculty of postgraduate professional training of physicians, sechenov First moscow state medical university</p></bio><bio xml:lang="ru"><p>Очный аспирант кафедры хирургии ФППоВ Первого Московского государственного медицинского университета им. И.М.Сеченова</p></bio><email>mail@vestnik-surgery.com</email><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><name><surname>Юнусов</surname><given-names>Б.Т</given-names></name><bio xml:lang="en"><p>postgraduate, Chair of surgery, Faculty of postgraduate professional training of physicians, sechenov First moscow state medical university</p></bio><bio xml:lang="ru"><p>Очный аспирант кафедры хирургии ФППоВ Первого Московского государственного медицинского университета им. И.М. Сеченова</p></bio><email>mail@vestnik-surgery.com</email><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><name><surname>Кешишев</surname><given-names>А.Г</given-names></name><bio xml:lang="en"><p>surgeon of the clinical hospital № 53, moscow</p></bio><bio xml:lang="ru"><p>врач–хирург хирургического отделения, Городская клиническая больница №53 г. Москвы</p></bio><email>mail@vestnik-surgery.com</email><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><name><surname>Виленский</surname><given-names>А.А</given-names></name><bio xml:lang="en"><p>surgeon of the clinical hospital № 53, moscow</p></bio><bio xml:lang="ru"><p>врач–хирург хирургического отделения, Городская клиническая больница №53 г. Москвы</p></bio><email>mail@vestnik-surgery.com</email><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><name><surname>Петросян</surname><given-names>Г.А</given-names></name><bio xml:lang="en"><p>Faculty of postgraduate professional training of physicians, chair of surgery, sechenov First moscow state medical university., resident of doctor</p></bio><bio xml:lang="ru"><p>Клинический ординатор кафедры хирургии ФППоВ Первого Московского государственного медицинского университета им. И.М. Сеченова</p></bio><email>goonar@list.ru</email><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><name><surname>Абрамов</surname><given-names>В.Н</given-names></name><bio xml:lang="en"><p>chief of Department of intensive Care, clinical hospital № 53, moscow</p></bio><bio xml:lang="ru"><p>зав. отделением реанимации, Городская клиническая больница №53 г. Москвы</p></bio><email>doc-abramov@yandex.ru</email><xref ref-type="aff" rid="aff2"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">i.m. sechenov First moscow state medical university, moscow, russian Federation&#13;
Clinical hospital № 53, moscow, russian Federation</institution></aff><aff><institution xml:lang="ru">Первый московский государственный медицинский университет им. И.М.Сеченова, Москва, Российская Федерация Городская клиническая больница № 53, Москва, Российская Федерация</institution></aff></aff-alternatives><aff-alternatives id="aff2"><aff><institution xml:lang="en">i.m. sechenov First moscow state medical university, moscow, russian Federation&#13;
Clinical hospital № 53, moscow, russian Federation</institution></aff><aff><institution xml:lang="ru">к.м.н., асс. кафедры хирургии ФППоВ Первого Московского государственного медицинского университета им. И.М. Сеченова</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2013-06-24" publication-format="electronic"><day>24</day><month>06</month><year>2013</year></pub-date><volume>6</volume><issue>2</issue><issue-title xml:lang="ru"/><fpage>140</fpage><lpage>147</lpage><history><date date-type="received" iso-8601-date="2016-04-27"><day>27</day><month>04</month><year>2016</year></date><date date-type="accepted" iso-8601-date="2016-04-27"><day>27</day><month>04</month><year>2016</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2013, ., ., ., ., ., ., ., .</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2013, Глабай В., Архаров А., Алиев А., Юнусов Б., Кешишев А., Виленский А., Петросян Г., Абрамов В.</copyright-statement><copyright-year>2013</copyright-year><copyright-holder xml:lang="en">., ., ., ., ., ., ., .</copyright-holder><copyright-holder xml:lang="ru">Глабай В., Архаров А., Алиев А., Юнусов Б., Кешишев А., Виленский А., Петросян Г., Абрамов В.</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">http://creativecommons.org/licenses/by-nc-nd/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://vestnik-surgery.com/journal/article/view/150">https://vestnik-surgery.com/journal/article/view/150</self-uri><abstract xml:lang="en"><p>Relevance The need to determine the frequency of occurrence of a speciŸc type of complication of "open" operations in severe pancreatitis, the timeliness of their recognition, the deŸnition of the indications for surgical or conservative treatment of intraoperative and early postoperative complications, the choice of surgical methods, the development of principles of postoperative management and rehabilitation of such patients. The purpose of the study Was to improve the results of the use of "open" surgery in patients with acute severe pancreatitis.Materials and Methods 6844 patients with acute pancreatitis were under surveillance for the last 20 years. 493 (7,3%) of them underwent surgical treatment. 322 had an "open" operative intervention, and in 102 (31.6%) identiŸed 197 intraoperative or early postoperative complications. Lien trauma was revealed intraoperationally with 7 patients, 3 cyst bleeding after dissection, 1 splenic artery bleeding and 1 parenchymal splenic bleeding. Among the early postoperative complications were revealed: arrosive hemorrhage 30,8%; pancreatic Ÿstulas 19,1%; hollow organ Ÿstulas – stomach 7,4%, duodenum 5,3%, small intestine 3,2%, colon 12,7%, cystoduodenal Ÿstulas 2,1%, stomach phlegmon 2,1%, acute cholecystitis 1,06%, trombotic complications 3,2%, purulent pleuritis 1,06%. Results and their discussion The main reason for acute severe pancreatitis intra and early post open packing operation complications are the inŸltration process on the intervention area, the involvement of the hollow organ wall into the purulent process, vessel deformation and the destruction of the pancreatic duct disruption. The primary prophylactic measures of the complications are adequate access, certain intraoperative tissue differentiation, unconŸned sequestrum elimination without force, the rejection of the acute removal of the necrotic tissues and the sanation relaparotomy with the application of local anesthesia each 48-72 hours.</p><p>The treatment tactics of the open packing operation complications is quite diversiŸed and can be either conservative or operative, palliative or resective and depend on the local changes in the intervention area and polyorganic deŸciency presence.</p><p>Conclusion The results of the treatment “open” packing operations complications in severe acute pancreatitis are achieved through </p><p>the use of our clinical guidelines developed in the management of patients with severe acute pancreatitis in all phases of treatment.</p><p> </p></abstract><trans-abstract xml:lang="ru"><p>1. Grishin I.N., Grits V.N., Lagodich S.N. Kisty podzheludochnoi zhelezy i ikh oslozhneniia [Pancreatic cysts and their complications]. Minsk, Vysheishaia shkola, 2009; 275 p. – (In Russian). 2. Baron T.H., Thaggard W.G., Morgan D.E., Stanley R.J. Endoscopic therapy for organized pancreatic necrosis. Gastroenterology, 1996; 111: 755-764. 3. Beger H., Isenmann R. Surgical management of necrotising pancreatitis. Surg. Clin. North. Am., 1999; 79: 783-800. 4. Benjamin P.T. Loveday, Anubhav Mittal, Anthony Philips, John A.Windsor. Minimally Invasive Management of Pancreatic Abscess, Pseudocyst : A Systematic Review of Current Guidelines. World J.Surg., 2008; 32: 2383 – 2394. 5. Bradley E.L. III. A clinically based classification system for acute pancreatitis. Arch. Surg., 1993; 128: 586-590. 6. Carter R., McKay C., Imrie C. Percutaneous necrosectomy and sinus tract endoscopy in management of infected pancreatic necrosis: an initial experience. Ann. Surg., 2001; 232: 175-180.</p><p>7. Connor S., Alexakis N., Raraty M.G. et al. Early and late complications after pancreatic necrosectomy. Surgery, 2005; 137: 5: 499-505. 8. Freeny P.C., Hauptmann E., Althaus S.J. et al. Percutaneous CT-guided catheter drainage of infected acute necrotizing pancreatitis: techniques and results. AJR Am. J. Roentgenol., 1998; 170: 969-975. 9. Gooszen H.G. Surgery in acute pancreatitis: open versus minimal invasive. Thesis of International conference of surgeons. Kaunas, Lithuania, 2007; 7-8. 10. Nicolas K.K.King, Ajith K.Siriwardena. European Survey of Surgical Strategies for the Management of Severe Acute Pancreatitis. Am. J. Gastroenterol., 2004; 99: 719-728. 11. Rau B., Pralle U., Uhl W., et al. Management of sterile necrosis in instances of severe acute pancreatitis. J. Am. Coll. Surg., 1995; 181: 279-288. 12. Uhl W., Warshaw A., Imrie C. et al. IAP Guidelanes for the surgical management of acute pancreatitis. Pancreatology, 2002; 2: 565-573.</p></trans-abstract><kwd-group xml:lang="en"><kwd>Acute pancreatitis</kwd><kwd>post-operative complications</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>Острый панкреатит</kwd><kwd>послеоперационные осложнения</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>1. Grishin I.N., Grits V.N., Lagodich S.N. Kisty podzheludochnoi zhelezy i ikh oslozhneniia [Pancreatic cysts and their complications]. Minsk, Vysheishaia shkola, 2009; 275 p.</mixed-citation></ref><ref id="B2"><label>2.</label><mixed-citation>2. Baron T.H., Thaggard W.G., Morgan D.E., Stanley R.J. EHndoskopicheskaya terapiya dlya organizovannyh pankreonekroza [Endoscopic therapy for organized pancreatic necrosis]. Gastroenterology, 1996; 111: 755-764.</mixed-citation></ref><ref id="B3"><label>3.</label><mixed-citation>3. Beger H., Isenmann R. 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