Journal of Experimental and Clinical SurgeryJournal of Experimental and Clinical SurgeryВестник экспериментальной и клинической хирургии2070-478X2409-143XVoronezh State Medical University named after N.N. Burdenko15610.18499/2070-478X-2015-8-1-111-119Original articlesОригинальные статьиUnknownMinimally Invasive Methods of Treatment Patients with Prostate CancerМалоинвазивные методы в лечении больных раком предстательной железыВельшерЛ.З.

Prof., State Prize Laureate, Honorary Doctor of Russia, Head of the Department of Oncology and Radiotherapy, A.I. Evdokimov Moscow State Medical and Dental University, director of the Cancer Center Central Clinical Hospital №2 named N.A. Semashko OAO "RZHD"

д.м.н., проф., Лауреат Государственных премий, Заслуженный врач РФ, зав. кафедрой онкологии и лучевой терапии Московского государственного медико-стоматологического университета им. А.И. Евдокимова, руководитель онкологического центра ОАО «РЖД» НУЗ ЦКБ №2 им Н.А. Семашко ОАО «РЖД»

author@vestnik-surgery.comСтахановМ.Л.

Prof. of the Department of Oncology and Radiotherapy, A.I. Evdokimov Moscow State Medical and Dental University, Head of the Department of laser medical technologies Cancer Center Central Clinical Hospital №2 named N.A. Semashko OAO "RZHD"

д.м.н., проф. кафедры онкологии и лучевой терапии Московского государственного медико-стоматологического университета им. А.И. Евдокимова, зав. отделением лазерных медицинских технологий онкологического центра ОАО «РЖД» НУЗ ЦКБ №2 им Н.А. Семашко ОАО «РЖД»

author@vestnik-surgery.comПушкарьД.Ю.

Prof., Honorary Doctor of Russia, Member of the Presidium of the Russian Society of Urologists, Head of the Department of Urology, A.I. Evdokimov Moscow State Medical and Dental University

д.м.н., проф., заслуженный врач РФ, член президиума Российского Общества Урологов, зав. кафедрой урологии Московского государственного медико-стоматологического университета им. А.И. Евдокимова;

author@vestnik-surgery.comКалининМ.Р

Prof., Honorary Doctor of Russia, Director of the Central Clinical Hospital №2 named N.A. Semashko OAO "RZHD"

д.м.н., проф., Заслуженный врач РФ, директор НУЗ ЦКБ №2 им. Н.А. Семашко ОАО «РЖД»

author@vestnik-surgery.comГорчакЮ.Ю.

PhD, Docent of the Department of Oncology and Radiotherapy, A.I. Evdokimov Moscow State Medical and Dental University

к.м.н., доцент кафедры онкологии и лучевой терапии Московского государственного медико-стоматологического университета им. А.И. Евдокимова

author@vestnik-surgery.comАникановаЕ.В,

Postgraduate of the Department of Oncology and Radiotherapy, A.I. Evdokimov Moscow State Medical and Dental University.

аспирант кафедры онкологии и лучевой терапии Московского государственного медико-стоматологического университета им. А.И. Евдокимова.

anikanova1801@gmail.comИшевскийГ.Б.

PhD, Head of the Department oncourology N.A. Semashko Cancer Center Central Clinical Hospital №2 OAO "RZHD"

к.м.н., зав. онкоурологическим отделением Онкологического центра НУЗ ЦКБ №2 им Н.А. Семашко ОАО «РЖД»

author@vestnik-surgery.comКостинЕ.Ю.

doctor oncourologist of the Department oncourology N.A. Semashko Cancer Center Central Clinical Hospital №2 OAO "RZHD"

врач онкоурологического отделения Онкологического центра НУЗ ЦКБ №2 им Н.А. Семашко ОАО «РЖД»

author@vestnik-surgery.comЧочуаГ.А.

PhD, Docent of the Department of Oncology and Radiotherapy, A.I. Evdokimov Moscow State Medical and Dental University

к.м.н., доцент кафедры онкологии и лучевой терапии Московского государственного медико-стоматологического университета им. А.И. Евдокимова.

author@vestnik-surgery.comA.I. Evdokimov Moscow State University of Medicine and Dentistry, 20/1 Delegatskaia Str., Moscow, 127473, Russian Federation N.A. Semashko Cancer Center Central Clinical Hospital №2 OAO "RZHD", 2 Budaiskaia Str., Moscow, 128129, Russian FederationМосковский государственный медико-стоматологический университет им. А.И. Евдокимова, ул. Делегатская, д. 20/1, Москва, 127473, Российская Федерация Онкологический центр ОАО «РЖД» при НУЗ «Центральная клиническая больница №2 им. Н.А. Семашко ОАО «РЖД», ул. Будайская, д. 2, Москва, 129128, Российская ФедерацияA.I. Evdokimov Moscow State University of Medicine and Dentistry, 20/1 Delegatskaia Str., Moscow, 127473, Russian FederationМосковский государственный медико-стоматологический университет им. А.И. Евдокимова, ул. Делегатская, д. 20/1, Москва, 127473, Российская ФедерацияN.A. Semashko Cancer Center Central Clinical Hospital №2 OAO "RZHD", 2 Budaiskaia Str., Moscow, 128129, Russian FederationОнкологический центр ОАО «РЖД» при НУЗ «Центральная клиническая больница №2 им. Н.А. Семашко ОАО «РЖД», ул. Будайская, д. 2, Москва, 129128, Российская Федерация24032015811111192704201627042016Copyright ©; 2015, ., ., ., ., ., ., ., ., .Copyright ©; 2015, Вельшер Л., Стаханов М., Пушкарь Д., Калинин М., Горчак Ю., Аниканова Е., Ишевский Г., Костин Е., Чочуа Г.2015., ., ., ., ., ., ., ., .Вельшер Л., Стаханов М., Пушкарь Д., Калинин М., Горчак Ю., Аниканова Е., Ишевский Г., Костин Е., Чочуа Г.http://creativecommons.org/licenses/by-nc-nd/4.0https://vestnik-surgery.com/journal/article/view/156

The incidence of prostate cancer has increased in recent decades. Radical prostatectomy and radiotherapy are the standard methods of radical treatment of patients with prostate cancer. The complications and reduced quality of life of patients often develop after radical treatment. These facts were the basis for the search and implementation of new minimally invasive treatments. Effective treatment of patients and reduce the number of complications there are goals of minimally invasive treatments. Information about modern methods of minimally invasive treatment of patients with prostate cancer, such as cryosurgical ablation, high-intensity focused ultrasound therapy is presented in this article. Furthermore, mechanisms of action, the process of treatment, oncological efficacy and possible complications are described. The article includes information on the experimental methods, such as interstitial thermotherapy and photodynamic therapy. International studies of use of these methods are given. In addition, the method electrochemical lysis is shown in this article, the results of clinical practice in patients with prostate cancer. Key words Prostate cancer, minimally invasive treatments, electrochemical lysis

В последние десятилетия отмечен рост заболеваемости раком предстательной железы. Стандартными методами радикального лечения больных раком простаты являются радикальная простатэктомия и лучевая терапия. Применение этих методов довольно часто сопровождается развитием осложнений и стойким снижением качества жизни пациентов. Это явилось основанием для поиска и внедрения  в клиническую практику новых малоинвазивных методов лечения, направленных на эффективное лечение больных при одновременном снижении числа возможных осложнений. В статье представлена информация о современных методах малоинвазивного лечения больных раком предстательной железы, таких как криохирургическая абляция, терапия высокоинтенсивным сфокусированным ультразвуком. Дано описание их механизмов действия, процесса лечения, онкологическая эффективность и возможные осложнения. Приведены исследования зарубежных авторов, посвященные применению новых экспериментальных методов лечения  – интерстициальной термотерапии и фотодинамической терапии. Дана характеристика метода электрохимического лизиса, представлены непосредственные результаты клинического применения у больных раком предстательной железы.

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