Journal of Experimental and Clinical SurgeryJournal of Experimental and Clinical SurgeryВестник экспериментальной и клинической хирургии2070-478X2409-143XVoronezh State Medical University named after N.N. Burdenko157310.18499/2070-478X-2022-15-2-182-187Review of literatureОбзор литературыUnknownThe Role of the Commensal Skin Microbiota in the Processes of Reparative Regeneration of Soft Tissue WoundsРоль комменсальной кожной микробиоты в процессах репаративной регенерации ран мягких тканейhttps://orcid.org/0000-0001-6567-7803TulupovAlexander AndreevichТулуповАлександр Андреевич
Russian Federation

junior researcher

Младший научный сотрудник

tulupov.a.a@yandex.ruhttps://orcid.org/0000-0002-9332-3858BeschastnovVladimir ViktorovichБесчастновВладимир Викторович
Russian Federation

M.D., associate professor, senior researcher

д.м.н., доцент, старший научный сотрудник

vvb748@mail.ruhttps://orcid.org/0000-0002-7008-4962PogodinIgor EvgenievichПогодинИгорь Евгеньевич
Russian Federation

Traumatologist-orthopedist, head of the burn department (adults)

Врач травматолог-ортопед, заведующий ожоговым отделением (взрослых)

pogigevg@yandex.ruhttps://orcid.org/0000-0002-8387-6344ShirokovaIrina YuryevnaШироковаИрина Юрьевна
Russian Federation

Ph.D, Head of the Bacteriological Laboratory of the RI of Preventive Medicine; associate professor of the department of epidemiology, microbiology and evidence-based medicine

Кандидат медицинских наук, заведующая бактериологической лабораторией НИИ профилактической медицины; доцент кафедры эпидемиологии, микробиологии и доказательной медицины

shirokova.i@yandex.ruhttps://orcid.org/0000-0002-7569-4866DudarevaElena VladimirovnaДудареваЕлена Владимировна
Russian Federation

Bacteriologist

Врач-бактериолог

dudareva.lena2010@yandex.ruhttps://orcid.org/0000-0002-6178-0202AndryukhinKirill ValerievichАндрюхинКирилл Валерьевич
Russian Federation

4th year student

студент 4 курса

johnny.andr@mail.ruhttps://orcid.org/0000-0001-9844-5638BadikovEmil FirdavisovichБадиковЭмиль Фирдависович
Russian Federation

Junior researcher

Младший научный сотрудник

docroutruyesou-492@yopmail.comUniversity clinic Federal State Budgetary Educational Institution of Higher Education «Privolzhsky Research Medical University» of the Ministry of HealthФедеральное государственное бюджетное образовательное учреждение высшего образования "Приволжский исследовательский медицинский университет" Министерства здравоохранения Российской ФедерацииUniversity clinic Federal State Budgetary Educational Institution of Higher Education «Privolzhsky Research Medical University» of the Ministry of HealthУниверситетская клиника федерального государственного бюджетного образовательного учреждения высшего образования "Приволжский исследовательский медицинский университет" Министерства здравоохранения Российской ФедерацииUniversity clinic Federal State Budgetary Educational Institution of Higher Education «Privolzhsky Research Medical University» of the Ministry of HealthУниверситетская клиника федерального государственного бюджетного образовательного учреждения высшего образования "Приволжский исследовательский медицинский университет"061120221521821871702202223042022Copyright ©; 2022, Voronezh N.N. Burdenko State Medical UniversityCopyright ©; 2022, ФГБОУ ВО ВГМУ им. Н.Н. Бурденко Минздрава России2022Voronezh N.N. Burdenko State Medical UniversityФГБОУ ВО ВГМУ им. Н.Н. Бурденко Минздрава Россииhttps://vestnik-surgery.com/journal/about/editorialPolicieshttps://vestnik-surgery.com/journal/article/view/1573

The issues of soft tissue wound management and combating complications of the wound process caused by colonization of the wound bed by pathogenic microflora are constantly in the field of view of surgical specialists. The steady growth of injuries accompanied by soft tissue damage and spread of antibiotic-resistant microflora prompt clinicians to preserve the body's natural defenses in order to improve tissue repair processes, thereby reducing hospital stay and achieving rational use of the economic resources of a health care facility. The article presents generalized data of scientific research arguing the significant contribution of representatives of the commensal skin microbiota to the processes of reparative regeneration of soft tissue wounds.

Вопросы лечения ран мягких тканей и борьбы с осложнениями раневого процесса, обусловленных колонизацией раневого ложа патогенной микрофлорой, постоянно находятся в поле зрения специалистов хирургического профиля. Неуклонный рост травм, сопровождающихся повреждением мягких тканей и распространение антибиотикорезистентной микрофлоры подталкивает клиницистов к сохранению естественных защитных сил организма с целью улучшения процессов тканевой репарации, за счет чего возможно сокращение сроков госпитализации и достигается рациональное использование экономических ресурсов медицинской организации. В статье представлены обобщенные данные научных исследований, аргументирующие существенный вклад представителей комменсальной кожной микробиоты на процессы репаративной регенерации ран мягких тканей.

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