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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="other" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Journal of Experimental and Clinical Surgery</journal-id><journal-title-group><journal-title xml:lang="en">Journal of Experimental and Clinical Surgery</journal-title><trans-title-group xml:lang="ru"><trans-title>Вестник экспериментальной и клинической хирургии</trans-title></trans-title-group></journal-title-group><issn publication-format="print">2070-478X</issn><issn publication-format="electronic">2409-143X</issn><publisher><publisher-name xml:lang="en">Voronezh State Medical University named after N.N. Burdenko</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">167</article-id><article-id pub-id-type="doi">10.18499/2070-478X-2013-6-2-148-154</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Original articles</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Оригинальные статьи</subject></subj-group><subj-group subj-group-type="article-type"><subject>Unknown</subject></subj-group></article-categories><title-group><article-title xml:lang="en">Profilaxis of Intraabdominal Adhesion in Patients with Mechanical Abdominal Trauma and Hemoperitoneum</article-title><trans-title-group xml:lang="ru"><trans-title>Профилактика развития внутрибрюшных спаек у больных с механической травмой живота, осложненной гемоперитонеумом</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name><surname>Лаврешин</surname><given-names>П.М</given-names></name><bio xml:lang="en"><p>prof., Head. Department of General Surgery of the Stavropol State Medical Academy</p></bio><bio xml:lang="ru"><p>д.м.н., проф. зав. кафедрой общей хирургии Ставропольской государственной медицинской академии</p></bio><email>author@vestnik-surgery.com</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name><surname>Гобеджишвили</surname><given-names>В.К</given-names></name><bio xml:lang="en"><p>MD, PhD, Assoc. Department of General Surgery of the Stavropol State Medical Academy</p></bio><bio xml:lang="ru"><p>к.м.н., доц. кафедры общей хирургии Ставропольской государственной медицинской академии</p></bio><email>Walker87@list.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name><surname>Гобеджишвили</surname><given-names>В.В</given-names></name><bio xml:lang="en"><p>intramural graduate student, Department of General Surgery of the Stavropol State Medical Academy</p></bio><bio xml:lang="ru"><p>очный аспирант кафедры общей хирургии Ставрополь- ской государственной медицинской академии</p></bio><email>v_lin87@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name><surname>Келасов</surname><given-names>И.Г</given-names></name><bio xml:lang="en"><p>post-graduate student, Department of General Surgery of the Stavropol State Medical Academy</p></bio><bio xml:lang="ru"><p>заочный аспирант кафедры общей хирургии Ставропольской государ- ственной медицинской академии</p></bio><email>author@vestnik-surgery.com</email><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">Stavropol State Medical University, Stavropol, Russian Federation</institution></aff><aff><institution xml:lang="ru">Ставропольский государственный медицинский университет, Ставрополь, Российская Федерация</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2013-06-24" publication-format="electronic"><day>24</day><month>06</month><year>2013</year></pub-date><volume>6</volume><issue>2</issue><issue-title xml:lang="ru"/><fpage>148</fpage><lpage>154</lpage><history><date date-type="received" iso-8601-date="2016-04-27"><day>27</day><month>04</month><year>2016</year></date><date date-type="accepted" iso-8601-date="2016-04-27"><day>27</day><month>04</month><year>2016</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2013, ., ., ., .</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2013, Лаврешин П., Гобеджишвили В., Гобеджишвили В., Келасов И.</copyright-statement><copyright-year>2013</copyright-year><copyright-holder xml:lang="en">., ., ., .</copyright-holder><copyright-holder xml:lang="ru">Лаврешин П., Гобеджишвили В., Гобеджишвили В., Келасов И.</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">http://creativecommons.org/licenses/by-nc-nd/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://vestnik-surgery.com/journal/article/view/167">https://vestnik-surgery.com/journal/article/view/167</self-uri><abstract xml:lang="en"><p>The purpose of the study Through the development of complex of diagnostic and treatment, events organization, aimed at the prevention of the development of abdominal adhesions, improve the results of treatment of patients after surgery for a mechanical abdominal trauma, complicated haemoperitoneum. Material and methods For clinical study was performed 83 patients with open and closed mechanical trauma of the abdomen, complicated by haemoperitoneum. In dynamic screening was used self constructed diagnostic magnoimmunsorbs-test system based on the antigen commissural complex. Definition of indicators of hemostasis was carried out using by method of NGOs «RENAM». Results and their discussion Modified by author the test system on the basis of magnoimmunsorbs and immobilised adhesive antigen allows with the high per-formance to predict the development of intraabdominal adhesions, to control of results by antiadhesion therapy. Develop a pathogenetically justified complex of therapeutic measures, directed on elimination of hypoxia in the tissues, activity normalization of the fibrinolitic blood system, the appointment of the antiadhesion drug, the gradual application of physical therapy. This complex allow to bettering the treatment results , to decrease adhesion development in postoperative period from 65% to 12,1% i.m. in 5,4 times. Conclusion In patients operated due to abdominal trauma, hemoperitoneum was founded statistic improved condition of medium hipocoagulation, decreased activity of fibrinoliticic blood system. In identification of the dynamic changes in amount of positive reactions Ag+At in different titres of blood serum can be determined the therapy starting date and estimated its effectiveness.</p></abstract><trans-abstract xml:lang="ru"><p>Цель исследования Путем разработки комплекса диагностических и лечебных мероприятий, направленных на профилак- тику развития внутрибрюшных спаек, улучшить результаты лечения больных, перенесших операции по поводу механиче- ской травмы живота, осложненной гемоперитонеумом. Материал и методы Клинические исследования проведены у 83 больных с открытой и закрытой механической травмой живота, осложненной гемоперитонеумом. Для исследования динамики аутоантителобразования применяли сконструи- рованную нами диагностическую магноиммуносорбентную тест-систему на основе антигенного спаечного комплекса. Определение показателей гемостаза производили по методу НПО «Ренам» набором коагулотест. Результаты и их обсуждение Модифицированная автором тест-система на основе магноиммуносорбентов и иммобили- зированныи спаечным антигеном позволяет с высокой эффективностью прогнозировать развитие внутрибрюшных спаек, контролировать результаты противоспаечной терапии. Разработан патогенетически обоснованный комплекс лечебных мероприятий, направленный на устранение гипоксии в тканях, нормализацию активности фибринолитической системы крови, назначение медикаментозных противоспаечных препаратов, поэтапного применения физиопроцедур. Предложен- ный комплекс диагностических и лечебных мероприятий позволил значительно улучшить результаты лечения наблюдае- мых больных, снизить в послеоперационном периоде развитие внутрибрюшных спаек с 65% до 12,1%, т.е. в 5,4 раза. Выводы У пациентов, оперированных по поводу механической травмы живота, гемоперитонеума, наблюдается стати- стически значимое сосотояние умеренной гиперкоагуляции, снижение активности фибринолитической системы крови. По динамике изменений количества положительных реакций Аг+Ат в разных титрах сыворотки крови у этих пациентов можно определять сроки начала противоспаечной терапии и оценивать ее эффективность.</p></trans-abstract><kwd-group xml:lang="en"><kwd>Mechanical abdominal trauma</kwd><kwd>abdominal cavities</kwd><kwd>adhesion process</kwd><kwd>test-system, prognosis</kwd><kwd>treatment</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>Механическая травма живота</kwd><kwd>брюшная полость</kwd><kwd>спаечный процесс</kwd><kwd>тест-система</kwd><kwd>прогнозирование</kwd><kwd>лечение</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>1. Baranov G.A., Karbovskii M.Iu. Otdalennye rezul'taty operativnogo ustraneniya spaechnoj kishechnoj neprohodimosti [Distant results of surgical</mixed-citation></ref><ref id="B2"><label>2.</label><mixed-citation>removal of adhesive intestinal obstruction]. 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