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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="other" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Journal of Experimental and Clinical Surgery</journal-id><journal-title-group><journal-title xml:lang="en">Journal of Experimental and Clinical Surgery</journal-title><trans-title-group xml:lang="ru"><trans-title>Вестник экспериментальной и клинической хирургии</trans-title></trans-title-group></journal-title-group><issn publication-format="print">2070-478X</issn><issn publication-format="electronic">2409-143X</issn><publisher><publisher-name xml:lang="en">Voronezh State Medical University named after N.N. Burdenko</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">175</article-id><article-id pub-id-type="doi">10.18499/2070-478X-2013-6-2-155-160</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Original articles</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Оригинальные статьи</subject></subj-group><subj-group subj-group-type="article-type"><subject>Unknown</subject></subj-group></article-categories><title-group><article-title xml:lang="en">The Choice of Synthetic Mesh to Surgical Treatment by I.L.Lichtenstein of Inguinal Hernia</article-title><trans-title-group xml:lang="ru"><trans-title>Выбор синтетического эндопротеза для хирургического лечения паховых грыж по I.L.Lichtenstein</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name><surname>Паршиков</surname><given-names>В.В</given-names></name><bio xml:lang="en"><p>MD, Professor, the Department of Hospital Surgery named after B.А. Korolyov, Nizhnii Novgorod State Medical Academy</p></bio><bio xml:lang="ru"><p>д.м.н., про- фессор кафедры госпитальной хирургии им. Б.А.Королева Нижегородской государственной ме- дицинской академии</p></bio><email>pv1610@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name><surname>Бабурин</surname><given-names>А.Б</given-names></name><bio xml:lang="en"><p>Surgeon, Nizhnii Novgorod City Hospital No.35</p></bio><bio xml:lang="ru"><p>врач-хирург го- родской больницы №35, г. Нижний Новгород</p></bio><email>mail@vestnik-surgery.com</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name><surname>Ходак</surname><given-names>В.А</given-names></name><bio xml:lang="en"><p>Surgeon, Nizhnii Novgorod City Hospital No.35</p></bio><bio xml:lang="ru"><p>врач-хирург город- ской больницы №35, г. Нижний Новгород</p></bio><email>mail@vestnik-surgery.com</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name><surname>Петров</surname><given-names>В.В</given-names></name><bio xml:lang="en"><p>Surgeon, Nizhnii Novgorod City Hospital No.35</p></bio><bio xml:lang="ru"><p>врач-хирург го- родской больницы №35, г. Нижний Новгород</p></bio><email>mail@vestnik-surgery.com</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name><surname>Дворников</surname><given-names>А.В</given-names></name><bio xml:lang="en"><p>PhD, Head of the Experimental Simulation Group, Central Scientific Research Laboratory of Scientific Research Institute of Applied and Fundamental Medicine, Nizhnii Novgorod State Medical Academy</p></bio><bio xml:lang="ru"><p>к.б.н., заведую- щий группой экспериментального моделирования Центральной научно-исследовательской лабора- тории Института прикладной и фундаментальной медицины Нижегородской государственной меди- цинской академии</p></bio><email>mail@vestnik-surgery.com</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name><surname>Миронов</surname><given-names>А.А</given-names></name><bio xml:lang="en"><p>PhD, Research Worker, the Department of Neurophysiology and Experimental Simulation, Central Scientific Research Laboratory of Scientific Research Institute of Applied and Fundamental Medicine, Nizhnii Novgorod State Medical Academy</p></bio><bio xml:lang="ru"><p>к.б.н., сотруд- ник группы экспериментального моделирования Центральной научно-исследовательской лабора- тории Института прикладной и фундаментальной медицины Нижегородской государственной меди- цинской академии</p></bio><email>mail@vestnik-surgery.com</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name><surname>Романов</surname><given-names>Р.В</given-names></name><bio xml:lang="en"><p>PhD, Tutor, the Department of Hospital Surgery named after B.А. Korolyov, Nizhnii Novgorod State Medical Academy</p></bio><bio xml:lang="ru"><p>к.м.н., ассистент ка- федры госпитальной хирургии им. Б.А.Королева Нижегородской государственной медицинской академии</p></bio><email>mail@vestnik-surgery.com</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name><surname>Цыбусов</surname><given-names>С.Н</given-names></name><bio xml:lang="en"><p>MD, Professor, Head of the Department of Operative Surgery and Topographic Anatomy, ViceRector for Academic Affairs, Nizhnii Novgorod State Medical Academy</p></bio><bio xml:lang="ru"><p>д.м.н., профессор, заведующий кафедрой оперативной хирургии и топографической анатомии Нижегородской госу- дарственной медицинской академии, проректор по учебной работе.</p></bio><email>mail@vestnik-surgery.com</email><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">Nizhny Novgorod State Medical Academy, Nizhnii Novgorod, Russian Federation&#13;
Central Scientific Research Laboratory Scientific Research Institute of Applied and Fundamental Medicine, Nizhnii Novgorod, &#13;
Russian Federation&#13;
City hospital №35, Nizhnii Novgorod, Russian Federation</institution></aff><aff><institution xml:lang="ru">Нижегородская государственная медицинская академия, Нижний Новгород, Российская Федерация Центральная научно-исследовательская лаборатория Института прикладной и фундаментальной медицины, Нижний Новгород, Российская Федерация Городская больница №35, Нижний Новгород, Российская Федерация</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2013-06-24" publication-format="electronic"><day>24</day><month>06</month><year>2013</year></pub-date><volume>6</volume><issue>2</issue><issue-title xml:lang="ru"/><fpage>155</fpage><lpage>160</lpage><history><date date-type="received" iso-8601-date="2016-04-27"><day>27</day><month>04</month><year>2016</year></date><date date-type="accepted" iso-8601-date="2016-04-27"><day>27</day><month>04</month><year>2016</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2013, ., ., ., ., ., ., ., .</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2013, Паршиков В., Бабурин А., Ходак В., Петров В., Дворников А., Миронов А., Романов Р., Цыбусов С.</copyright-statement><copyright-year>2013</copyright-year><copyright-holder xml:lang="en">., ., ., ., ., ., ., .</copyright-holder><copyright-holder xml:lang="ru">Паршиков В., Бабурин А., Ходак В., Петров В., Дворников А., Миронов А., Романов Р., Цыбусов С.</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">http://creativecommons.org/licenses/by-nc-nd/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://vestnik-surgery.com/journal/article/view/175">https://vestnik-surgery.com/journal/article/view/175</self-uri><abstract xml:lang="en"><p>Relevance The basic technique of inguinal hernia repair is Lichtenstein procedure. This operation based on prosthetic repair of posterior wall of inguinal canal. The question of male infertility after Lichtenstein repair is to date known. The recommendations to choice of synthetic mesh for surgical treatment of inguinal hernia in males are to date not presented. The purpose of study is the choice of synthetic mesh for inguinal hernia repair in males. Materials and methods There was performed the simulation of Lichtenstein plasty in rabbits. The standard polypropylene (PP Std), light polypropylene (PP Light), polyvinylidene fluoride (PVDF) and reperene (R) meshes were used. Area of implantation was explored in 3 – 6 months. Macroscopic changes were estimated by special score. The data were by Mann – Whitney analyzed. Results and their discussion The maximal scar process was associated with PP Std. Medium scar process was noted after PP Light implantation. Minimal scar connective tissue was observed after PVDF plasty, but lower – in R cases (p=0,018). Conclusion We marked than after PP Std plasty strong scars developed with involvement of ductus deferens. This phenomenon is a base for ductus deferens obliteration, obstructive azoospermia and male’s infertility. The routine use of PP Std meshes to the Lichtenstein technique in young males with inguinal hernias is inadvisable. The possibility of PP Light use need of further researches. Some good results are associated with PVDF and R implantation</p></abstract><trans-abstract xml:lang="ru"><p>Актуальность Базовым способом операции при паховой грыже является техника I.L.Lichtenstein, основанная на протези- ровании полипропиленовой сеткой задней стенки пахового канала. Имеются данные о развитии мужской инфертильности после такого вмешательства. Четких рекомендаций относительно применения того или иного материала сетки для не- натяжной пластики до настоящего времени нет. Цель исследования Обосновать выбор синтетического материала для операции при паховой грыже у мужчин. Материал и методы В эксперименте на кроликах моделирована пластика по I.L.Lichtenstein. Применены сетки из стан- дартного полипропилена (PP Std), легкие полипропиленовые эндопротезы (PP Light), имплантаты из поливинилиденфто- рида (PVDF) и реперена (R). Зона пластики оценена макроскопически после выведения животных из эксперимента в сроки до 6 месяцев. Результаты и их обсуждение Максимальный рубцовый процесс в зоне ductus deferens оказался ассоциирован с применени- ем сетки PP Std, умеренно выраженный - PP Light, слабо выраженный – PVDF и минимальный – R (p=0,018). Выводы В эксперименте PP Std индуцирует грубый рубцовый процесс в зоне пахового канала с вовлечением ductus deferens. Указанный феномен является морфологической основой для развития в последующем обструктивной азооспермии и муж- ской инфертильности. Рутинное применение данного материала у мужчин репродуктивного возраста для пластики па- хового канала по методике Lichtenstein нежелательно. Возможность применения PP Light требует дальнейшего изучения. Относительно благоприятные результаты ассоциированы с применением PVDF и R.</p></trans-abstract><kwd-group xml:lang="en"><kwd>inguinal hernia</kwd><kwd>mesh</kwd><kwd>tension – free plasty</kwd><kwd>Lichtenstein</kwd><kwd>polypropylene</kwd><kwd>polyvinylidene fluoride</kwd><kwd>reperene</kwd><kwd>fertility</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>паховая грыжа</kwd><kwd>ненатяжная пластика</kwd><kwd>сетка, фертильность, полипропилен</kwd><kwd>поливинилиденфторид</kwd><kwd>ре- перен</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>1. Vinnik Iu.S. 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