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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="research-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Journal of Experimental and Clinical Surgery</journal-id><journal-title-group><journal-title xml:lang="en">Journal of Experimental and Clinical Surgery</journal-title><trans-title-group xml:lang="ru"><trans-title>Вестник экспериментальной и клинической хирургии</trans-title></trans-title-group></journal-title-group><issn publication-format="print">2070-478X</issn><issn publication-format="electronic">2409-143X</issn><publisher><publisher-name xml:lang="en">Voronezh State Medical University named after N.N. Burdenko</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">1839</article-id><article-id pub-id-type="doi">10.18499/2070-478X-2025-18-3-208-212</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Cases from practice</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Случаи из практики (архивный)</subject></subj-group><subj-group subj-group-type="article-type"><subject>Research Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">A giant thymolipoma of the anterior mediastinum extending into the right hemithorax: a rare clinical case</article-title><trans-title-group xml:lang="ru"><trans-title>Гигантская тимолипома переднего средостения с распространением в правый гемиторакс. Редкий клинический случай</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Pechetov</surname><given-names>Aleksey Aleksandrovich</given-names></name><name xml:lang="ru"><surname>Печетов</surname><given-names>Алексей Александрович</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Ph.D., Head</p></bio><bio xml:lang="ru"><p>к.м.н., заведующий хирургическим торакальным отделением</p></bio><email>pechetov@ixv.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Gulova</surname><given-names>Natalya Vladimirovna</given-names></name><name xml:lang="ru"><surname>Гулова</surname><given-names>Наталия Владимировна</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Surgeon of the Thoracic Surgery Department</p></bio><bio xml:lang="ru"><p>врач-хирург, хирургическое торакальное отделение</p></bio><email>nataliya-gulova@yandex.ru</email><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">A.V. Vishnevsky National Medical Research Center</institution></aff><aff><institution xml:lang="ru">Национальный медицинский исследовательский центр хирургии им. А.В. Вишневского</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2025-10-02" publication-format="electronic"><day>02</day><month>10</month><year>2025</year></pub-date><volume>18</volume><issue>3</issue><issue-title xml:lang="en">Journal of Experimental and Clinical Surgery</issue-title><issue-title xml:lang="ru">Вестник экспериментальной и клинической хирургии</issue-title><fpage>208</fpage><lpage>212</lpage><history><date date-type="received" iso-8601-date="2024-10-11"><day>11</day><month>10</month><year>2024</year></date><date date-type="accepted" iso-8601-date="2025-04-02"><day>02</day><month>04</month><year>2025</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2025, Voronezh N.N. Burdenko State Medical University</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2025, ФГБОУ ВО ВГМУ им. Н.Н. Бурденко Минздрава России</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="en">Voronezh N.N. Burdenko State Medical University</copyright-holder><copyright-holder xml:lang="ru">ФГБОУ ВО ВГМУ им. Н.Н. Бурденко Минздрава России</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/" start_date="2028-10-02"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://vestnik-surgery.com/journal/about/editorialPolicies</ali:license_ref></license></permissions><self-uri xlink:href="https://vestnik-surgery.com/journal/article/view/1839">https://vestnik-surgery.com/journal/article/view/1839</self-uri><abstract xml:lang="en"><p>Thymolipoma is a rare benign neoplasm of the chest cavity. Due to the long asymptomatic course, this pathology is detected in patients accidentally or when the tumor reaches gigantic sizes, when the compression syndrome of the chest organs and mediastinum manifests. Diagnosis of this tumor is difficult due to the variety of neoplasms of the anterior mediastinum. Detecting tumor tissue based to CT data is not difficult. However, verification of the diagnosis causes a number of difficulties due to the low information content of the obtained biopsy, which demonstrates only the presence of fatty tissue. When determining the exact diagnosis of "thymolipoma", the main treatment option is surgical removal of the tumor. The surgical approach should be chosen taking into account its size and topographic characteristics. This article presents a rare clinical observation of a patient with a giant thymolipoma of the anterior mediastinum with extension to the right hemithorax, who underwent radical surgical treatment through a sternotomy approach.</p></abstract><trans-abstract xml:lang="ru"><p>Тимолипома — редкое доброкачественное новообразование грудной полости. Из-за длительного бессимптомного течения данную патологию обнаруживают у пациентов случайно или по достижении гигантских размеров опухоли, когда манифестирует синдром компрессии органов грудной клетки и средостения. Диагностика данной опухоли сложна вследствие многообразия новообразований переднего средостения. Распознать наличие опухолевой ткани по данным КТ не вызывает трудностей. Однако верификация диагноза вызывает ряд сложностей в связи с низкой информативностью получаемого биоптата, демонстрирующего лишь наличие жировой ткани. При определении точного диагноза «тимолипома» основной метод лечения – хирургическое удаление опухоли. Оперативный доступ должен быть выбран с учетом ее размеров и топографических характеристик. В настоящей статье представлено редкое клиническое наблюдение пациента с гигантской тимолипомой переднего средостения с распространением в правый гемиторакс, которому было выполнено радикальное хирургическое лечение через стернотомный доступ.</p></trans-abstract><kwd-group xml:lang="en"><kwd>thymoma</kwd><kwd>thymolipoma</kwd><kwd>sternotomy</kwd><kwd>thymus tumor</kwd><kwd>mediastinal lipoma</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>тимома</kwd><kwd>тимолипома</kwd><kwd>стернотомия</kwd><kwd>опухоль тимуса</kwd><kwd>медиастинальная липома</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Roden AC, Fang W, Shen Y, Carter BW, White DB, Jenkins SM, Spears GM, Molina JR, Klang E, Segni MD, Ackman JB, Sanchez EZ, Girard N, Shumeri E, Revel MP, Chassagnon G, Rubinowitz A, Dicks D, Detterbeck F, Ko JP, Falkson CB, Sigurdson S, Segreto S, Del Vecchio S, Palmieri G, Ottaviano M, Marino M, Korst R, Marom EM. 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