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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="research-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Journal of Experimental and Clinical Surgery</journal-id><journal-title-group><journal-title xml:lang="en">Journal of Experimental and Clinical Surgery</journal-title><trans-title-group xml:lang="ru"><trans-title>Вестник экспериментальной и клинической хирургии</trans-title></trans-title-group></journal-title-group><issn publication-format="print">2070-478X</issn><issn publication-format="electronic">2409-143X</issn><publisher><publisher-name xml:lang="en">Voronezh State Medical University named after N.N. Burdenko</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">1872</article-id><article-id pub-id-type="doi">10.18499/2070-478X-2025-18-3-195-207</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Cases from practice</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Случаи из практики</subject></subj-group><subj-group subj-group-type="article-type"><subject>Research Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">Combined pancreatic solid-pseudo-papillary tumor and spleen lesions: diagnosis complexities in determining treatment tactics</article-title><trans-title-group xml:lang="ru"><trans-title>Сочетание солидно-псевдопапиллярной опухоли поджелудочной железы и образований селезёнки: сложности диагностики при определении тактики лечения</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Stepanova</surname><given-names>Yulia Alexandrovna</given-names></name><name xml:lang="ru"><surname>Степанова</surname><given-names>Юлия Александровна</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>M.D., Prof., Senior Researcher, Department of Ultrasound department</p></bio><bio xml:lang="ru"><p>д.м.н., профессор, старший научный сотрудник отделения ультразвуковой диагностики</p></bio><email>stepanovaua@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Ionkin</surname><given-names>Dmitry Anatolevich</given-names></name><name xml:lang="ru"><surname>Ионкин</surname><given-names>Дмитрий Анатольевич</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>PhD, Associate Professor of the Educational Department, Surgeon of the Department of Abdominal Surgery</p></bio><bio xml:lang="ru"><p>к.м.н., доцент образовательного отдела, врач-хирург отдела абдоминальной хирургии</p></bio><email>da.ionkin@gmail.com</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Alimurzaeva</surname><given-names>Maksalina Zakaryaevna</given-names></name><name xml:lang="ru"><surname>Алимурзаева</surname><given-names>Максалина Закарьяевна</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>assistant at Radiology Diagnostics and Radiation Therapy Department with a course in Ultrasound Diagnostics</p></bio><bio xml:lang="ru"><p>ассистент кафедры лучевой диагностики и лучевой терапии с курсом ультразвуковой диагностики</p></bio><email>maksalina1992@yandex.ru</email><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Arutyunov</surname><given-names>Ovanes Robertovich</given-names></name><name xml:lang="ru"><surname>Арутюнов</surname><given-names>Ованес Робертович</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>surgeon of Abdominal Surgery Department</p></bio><bio xml:lang="ru"><p>врач-хирург отделения абдоминальной хирургии</p></bio><email>arutyunov_ovanes@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Markov</surname><given-names>Pavel Viktorovich</given-names></name><name xml:lang="ru"><surname>Марков</surname><given-names>Павел Викторович</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Doct. of Med. Scien., Head of Abdominal Surgery Department</p></bio><bio xml:lang="ru"><p>д.м.н., заведующий отделением абдоминальной хирургии</p></bio><email>pvmarkov@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Shirokov</surname><given-names>Vadim Sergeevich</given-names></name><name xml:lang="ru"><surname>Широков</surname><given-names>Вадим Сергеевич</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>radiologist of Roentgenology and Magnetic Resonance Department</p></bio><bio xml:lang="ru"><p>врач-рентгенолог отделения рентгенологии и магнитно-резонансных исследований</p></bio><email>vadimshirokov@yandex.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Spitsyna</surname><given-names>Anastasia Igorevna</given-names></name><name xml:lang="ru"><surname>Спицына</surname><given-names>Анастасия Игоревна</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>1st year resident in the specialty «radiology»</p></bio><bio xml:lang="ru"><p>ординатор 1-го года обучения по специальности «лучевая диагностика» </p></bio><email>vostri2013@yandex.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Glotov</surname><given-names>Andrey Vyacheslavovich</given-names></name><name xml:lang="ru"><surname>Глотов</surname><given-names>Андрей Вячеславович</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>pathologist of pathological department</p></bio><bio xml:lang="ru"><p>врач-патологоанатом патологоанатомического отделения </p></bio><email>andrew.glotov@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">A.V. Vishnevsky National Medical Research Center of Surgery</institution></aff><aff><institution xml:lang="ru">Национальный медицинский исследовательский центр хирургии им. А.В. Вишневского</institution></aff></aff-alternatives><aff-alternatives id="aff2"><aff><institution xml:lang="en">Dagestan State Medical University</institution></aff><aff><institution xml:lang="ru">Дагестанский государственный медицинский университет</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2025-10-02" publication-format="electronic"><day>02</day><month>10</month><year>2025</year></pub-date><volume>18</volume><issue>3</issue><issue-title xml:lang="en">Journal of Experimental and Clinical Surgery</issue-title><issue-title xml:lang="ru">Вестник экспериментальной и клинической хирургии</issue-title><fpage>195</fpage><lpage>207</lpage><history><date date-type="received" iso-8601-date="2025-02-24"><day>24</day><month>02</month><year>2025</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2025, Stepanova Y.A., Ionkin D.A., Alimurzaeva M.Z., Arutyunov O.R., Markov P.V., Shirokov V.S., Spitsyna A.I., Glotov A.V.</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2025, Степанова Ю.А., Ионкин Д.А., Алимурзаева М.З., Арутюнов О.Р., Марков П.В., Широков В.С., Спицына А.И., Глотов А.В.</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="en">Stepanova Y.A., Ionkin D.A., Alimurzaeva M.Z., Arutyunov O.R., Markov P.V., Shirokov V.S., Spitsyna A.I., Glotov A.V.</copyright-holder><copyright-holder xml:lang="ru">Степанова Ю.А., Ионкин Д.А., Алимурзаева М.З., Арутюнов О.Р., Марков П.В., Широков В.С., Спицына А.И., Глотов А.В.</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/" start_date="2028-10-02"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">http://creativecommons.org/licenses/by-nc-nd/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://vestnik-surgery.com/journal/article/view/1872">https://vestnik-surgery.com/journal/article/view/1872</self-uri><abstract xml:lang="en"><p>Solid pseudopapillary tumors (SPTs) are rare neoplasms, which account for less than 2% of exocrine pancreatic tumors. These are low-grade epithelial malignancies. Currently, there are no data on SPT metastasis to the spleen in the literature. However, due to the rare SPT incidence and the ongoing accumulation and data analysis on these type of tumors globally, the presence of a combined cystic-solid structure lesion in the spleen does not allow us to exclude such a situation.</p> <p>Two clinical cases of SPT combined with focal spleen lesions are presented. The first one is with a cystic lesion verified as cavernous spleen lymphangioma according to the morphology of the removed lesion. Despite the fact that the splenic lesions included in the differential series during examination were benign, the size of the lesion and the risk of its rupture demonstrated the advisability of spleen resection performing.</p> <p>The second one is combined with multiple spleen hemangiomas verified by preoperative MSCT, which allowed performing a sparing operation - median resection (tumor enucleation) of the pancreatic head.</p> <p>Thus, а thorough examination of patients with combined focal lesions, one of which being SPT, a tumor with malignant potential, allows us to clearly determine the entire volume of the lesion and determine the correct surgical tactics.</p></abstract><trans-abstract xml:lang="ru"><p>Солидно-псевдопапиллярные опухоли (СППО) являются редким новообразованием, которое составляет менее 2% экзокринных опухолей поджелудочной железы. Это эпителиальные злокачественные новообразования низкой степени злокачественности. В настоящее время в литературе не имеется данных о метастазировании СППО в селезёнку. Однако, в силу редкой встречаемости СППО и идущей в настоящее время в мире аккумуляции и анализе данных об этих опухолях, наличие в селезёнке сочетанного поражения кистозно-солидной структуры не позволяет исключить такую ситуацию.</p> <p>Представлены два клинических наблюдения СППО в сочетании с очаговыми образованиями селезенки. Первое - с кистозным образованием, верифицированным как кавернозная лимфангиома селезенки по данным морфологического исследования удаленного образования. Несмотря на то, что выставленные в дифференциальный ряд образования селезёнки были доброкачественными, размеры очага и угроза его разрыва показали целесообразность выполнение резекции селезёнки с образованием.</p> <p>Второе - в сочетании с множественными гемангиомами селезёнки, верифицированным по данным дооперационного МСКТ, что позволило выполнить щадящую операцию в объеме срединной резекции (энуклеации опухоли) головки поджелудочной железы.</p> <p>Таким образом, тщательное обследование пациентов с сочетанными очаговыми образованиями, одним из которых является СППО, имеющее злокачественный потенциал, позволяет четко определить весь объем поражения и определить корректную хирургическую тактику.</p></trans-abstract><kwd-group xml:lang="en"><kwd>pancreatic solid pseudopapillary tumor</kwd><kwd>splenic lesion</kwd><kwd>splenic metastasis</kwd><kwd>combination</kwd><kwd>diagnostics</kwd><kwd>treatment</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>солидно-псевдопапиллярная опухоль поджелудочной железы</kwd><kwd>образование селезенки</kwd><kwd>метастаз в селезенку</kwd><kwd>сочетание</kwd><kwd>диагностика</kwd><kwd>лечение</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Frantz V.K. 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