Journal of Experimental and Clinical SurgeryJournal of Experimental and Clinical SurgeryВестник экспериментальной и клинической хирургии2070-478X2409-143XVoronezh State Medical University named after N.N. Burdenko20010.18499/2070-478X-2013-6-1-107-113Original articlesОригинальные статьиUnknownTreatment of Chronic Cystitis in ChildrenЛечение хронического цистита у детейСлизовскийГ.В.

Md, Assoc. Surgical diseases of Childhood, Siberian State Medical university

к.м.н., доц. кафедры детских хирургических болезней Сибирского государственного медицинского университета

sgv5858@mail.ruГудковА.В.

director of the institute of Medical shape memory materials, Tomsk State university

sgv5858@mail.ruКужеливскийИ.И.

Ass. Surgical diseases of Childhood, Siberian State Medical university

асс. кафедры детских хирургических болезней Сибирского государственного медицинского университета

kuzhel@rambler.ruШикуноваЯ.В.

Graduate student of children's surgical diseases of the Siberian State Medical university

аспирант кафедры детских хирургических болезней Сибирского государственного медицинского университета

yana-z@mail.ruSiberian State Medical University, Tomsk, Russian FederationСибирский государственный медицинский университет, Томск, Российская Федерация24032013611071132704201627042016Copyright ©; 2013, ., ., ., .Copyright ©; 2013, Слизовский Г., Гудков А., Кужеливский И., Шикунова Я.2013., ., ., .Слизовский Г., Гудков А., Кужеливский И., Шикунова Я.http://creativecommons.org/licenses/by-nc-nd/4.0https://vestnik-surgery.com/journal/article/view/200

Chronic inflammatory processes of the urinary bladder’s wall dominate in the structure of urologic diseases in children, but the issue of their treatment still remains very acute. Despite the use of modern methods of treatment, children with chronic recurrent cystitis constitute a significant part of the total number of hospitalized patients (19 to 21%). In recent years quite many morphological studies of the bladder’s mucosa during inflammatory diseases were held. However, the mechanism that leads to the damage of the urothelium in chronic cystitis and factor that determines the type of metaplasia during inflammation of the bladder are unclear. Endoscopic examination, in some cases, does not allow differentiating inflammatory from tumor-like lesions of the mucosa. Destructive lesions of the bladder’s mucosa occur during exacerbation of chronic inflammation or severe, far gone acute inflammation. Therefore, conducting endovesical biopsy is necessary for clarifying forms of chronic cystitis and identifying urothelial hyperplasia or dysplasia and is critical in the diagnosis of diseases of the urinary bladder. It is still unclear under what endoscopic and morphological forms of recurrent cystitis in children neurogenic bladder disorders are more frequent and for what form of recurrent cystitis most pronounced neurogenic bladder dysfunctions are more likely to occur. The nature and extent of neurogenic disorders in children with various forms of recurrent cystitis in the late periods after antireflux surgeries remain unexplored.

Хронические воспалительные процессы стенки мочевого пузыря занимают лидирующие позиции в структуре урологических заболеваний у детей, а проблема лечения по-прежнему остаётся весьма острой. Несмотря на применение современных методов терапии и способов лечения дети с хроническим рецидивирующим циститом (ХЦ) составляют значительную часть от общего числа госпитализированных больных (от 19 до 21%). В последние годы проведено достаточно много морфологических исследований слизистой оболочки мочевого пузыря при воспалительных заболеваниях. Однако остаётся неясным механизм, приводящий к повреждению уротелия при ХЦ, и что определяет тип метаплазии при воспалении мочевого пузыря. Эндоскопическое исследование в некоторых случаях не позволяет дифференцировать воспалительные и опухолеподобные поражения слизистой. Деструктивные поражения слизистой мочевого пузыря встречаются при обострении хронического воспаления или при выраженном, и далеко зашедшем остром воспалении. Поэтому, проведение эндовезикальной биопсии необходимо для уточнения формы ХЦ и выявления уротелиальной гиперплазии или дисплазии, и имеет решающее значение в диагностике заболеваний мочевого пузыря. Так до сих пор неясно, при каких эндоскопических и морфологических формах рецидивирующего цистита у детей чаще отмечаются нейрогенные расстройства мочеиспускания и для какой формы рецидивирующего цистита характерны наиболее выраженные нейрогенные нарушения функций мочевого пузыря. Остаются неизученными характер и степень нейрогенных нарушений у детей с различными формами рецидивирующего цистита в отдаленные сроки после антирефлюксных операций

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