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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="other" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Journal of Experimental and Clinical Surgery</journal-id><journal-title-group><journal-title xml:lang="en">Journal of Experimental and Clinical Surgery</journal-title><trans-title-group xml:lang="ru"><trans-title>Вестник экспериментальной и клинической хирургии</trans-title></trans-title-group></journal-title-group><issn publication-format="print">2070-478X</issn><issn publication-format="electronic">2409-143X</issn><publisher><publisher-name xml:lang="en">Voronezh State Medical University named after N.N. Burdenko</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">259</article-id><article-id pub-id-type="doi">10.18499/2070-478X-2013-6-4-467-474</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>New in surgery</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Новое в хирургии (архивный)</subject></subj-group><subj-group subj-group-type="article-type"><subject>Unknown</subject></subj-group></article-categories><title-group><article-title xml:lang="en">Experimental Substantiation New Ways of Spleno- and Mesorenal Anastomosis</article-title><trans-title-group xml:lang="ru"><trans-title>Экспериментальное обоснование новых способов сплено- и мезентери- коренальных анастомозов при портальной гипертензии</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name><surname>Третьяков</surname><given-names>А.А.</given-names></name><bio xml:lang="en"><p> MD, professor, head of Orenburg medical academy surgery department</p></bio><bio xml:lang="ru"><p> д.м.н., профессор, зав. кафедрой хирургии Оренбургской государственной медицинской академии</p></bio><email>author@vestnik-surgery.com</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name><surname>Каган</surname><given-names>И.И.</given-names></name><bio xml:lang="en"><p>MD, professor of S.S. Mikhaylov's operational surgery and clinical anatomy department.</p></bio><bio xml:lang="ru"><p> д.м.н., профессор кафедры оперативной хирургии и клинической анатомии им. С.С. Михайлова Оренбургской государственной медицинской академии</p></bio><email>author@vestnik-surgery.com</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name><surname>Нагорнов</surname><given-names>П.В.</given-names></name><bio xml:lang="en"><p>assistant of chair hospital surgery, urology</p></bio><bio xml:lang="ru"><p>к.м.н., ассистент кафедры госпитальной хирургии, урологии Оренбургской государственной медицинской академии</p></bio><email>pvnagornov@pochta.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name><surname>Смолевский</surname><given-names>В.С.</given-names></name><bio xml:lang="en"><p> surgeon, graduate student chair of surgery ORGMA.</p></bio><bio xml:lang="ru"><p>врач хирург ООПТД, заочный аспирант кафедры хирургии Оренбургской государственной медицинской академии</p></bio><email>author@vestnik-surgery.com</email><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">Orenburg State Medical Academy, 6 Sovetskaia Str., Orenburg, 460000, Russian Federation</institution></aff><aff><institution xml:lang="ru">Оренбургская государственная медицинская академия, Оренбург, Российская Федерация</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2013-12-24" publication-format="electronic"><day>24</day><month>12</month><year>2013</year></pub-date><volume>6</volume><issue>4</issue><issue-title xml:lang="ru"/><fpage>467</fpage><lpage>474</lpage><history><date date-type="received" iso-8601-date="2016-04-28"><day>28</day><month>04</month><year>2016</year></date><date date-type="accepted" iso-8601-date="2016-04-28"><day>28</day><month>04</month><year>2016</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2013, Voronezh N.N. Burdenko State Medical University</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2013, ФГБОУ ВО ВГМУ им. Н.Н. Бурденко Минздрава России</copyright-statement><copyright-year>2013</copyright-year><copyright-holder xml:lang="en">Voronezh N.N. Burdenko State Medical University</copyright-holder><copyright-holder xml:lang="ru">ФГБОУ ВО ВГМУ им. Н.Н. Бурденко Минздрава России</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://vestnik-surgery.com/journal/about/editorialPolicies</ali:license_ref></license></permissions><self-uri xlink:href="https://vestnik-surgery.com/journal/article/view/259">https://vestnik-surgery.com/journal/article/view/259</self-uri><abstract xml:lang="en"><p>Relevance Portocaval shunting is one of the main methods for prevention of gastroesophageal bleedings at patients with a portal hypertension syndrome. From proposed methods portocaval shunting most frequently used anastomosis with the roots of the portal vein - the splenic and superior mesenteric veins. However, the vascular anastomosis with the roots of the portal vein are often accompanied by complications, including thrombosis of fistulas and recurrence of gastroesophageal bleeding. This is caused by a small caliber of shunted vessels. In addition recurrent gastroesophageal bleeding is caused by excessive high portal pressure, arising as a result of hydrodynamic resistance at the mouth of the anastomosis, flutter blood flow, collapsing walls of the blood vessels, deformation of the inosculate vessels. For improving portocaval shunting results may be the introduction of microsurgical techniques and the operating methods of external fixation the vascular wall, creating a frame mechanism for the prevention of anastomotic valve structures. The purpose of the study The aim of the study was an experimental anatomical study and development of new microsurgical frame end-to-end splenorenal and mesorenal anastomosis in portal hypertension. Materials and methods The section on anatomy justification of microsurgical spleno- and mesorenal anastomosis performed on a section material (54 human cadavers). The study of topography and anatomy features of splenic, renal and superior mesenteric veins were conducted, their morphological characteristics, the histology characteristics of vascular anastomosis, the parameters of their tightness and mechanical strength. Experimental studies carried out on 48 mongrel dogs. There have been five sets of experiments. The analyses of morphological and functional status of improved vascular anastomosis in the short and long periods after surgery were accomplished. Results and their discussion There are developed new ways of microsurgical organ-save splenorenal and mesorenal anastomosis. New data on the dynamics of the vascular healing at various periods after reconstructive surgery, their morphological and functional characteristics were received. Conclusion Results of the study show that the use of microsurgical techniques in combination with an external frame of demineralized bone can create portocaval anastomosis with preservation of the kidney and spleen, to ensure good functioning of the anastomosis without the use of anticoagulants</p></abstract><trans-abstract xml:lang="ru"><p>Актуальность Портокавальное шунтирование остается одним из основных методов профилактики гастроэзофагеаль- ных кровотечений у больных с синдромом портальной гипертензии. Из десятков предложенных вариантов портокавальных анастомозов наиболее часто применяются анастомозы с корнями воротной вены – селезеночной и верхней брыжеечной венами. Однако сосудистые анастомозы с корнями воротной вены, из-за небольшого калибра анастомозируемых сосудов, часто сопровождаются осложнениями, среди которых тромбозу соустий и рецидиву гастроэзофагеальных кровотечений принадлежит основная роль. Причиной рецидива желудочно-пищеводных кровотечений, кроме тромбоза соустий, явля- ется избыточное высокое портальное давление, вследствие возникающего гидродинамического сопротивления в устье анастомоза, вызванного флаттерным потоком крови, схлопыванием коллапсирующих стенок сосудов, что сопровожда- ется деформацией сосудов, приобретающих щелевидную форму. Одним из путей улучшения результатов портокавально- го шунтирования может явиться внедрение микрохирургической техники оперирования и разработка способов внешней фиксации сосудистой стенки путем создания каркасного механизма в области анастомоза для профилактики образования клапанных структур. Цель исследования Анатомо-экспериментальное обоснование и разработка новых микрохирургических каркасных конце- концевых спленоренальных и мезентерикоренального анастомоза при портальной гипертензии. Материал и методы Раздел по анатомическому обоснованию микрохирургических сплено- и мезентерикоренальных ана- стомозов выполнен на органокомлексах, полученных от 54 трупов людей обоего пола. Проводилось изучение топографо- анатомических особенностей селезеночной, почечной и верхней брыжеечной вен, их морфологических характеристик, ги- стотопографических характеристик сосудистых анастомозов, параметров их герметичности и механической прочности. Экспериментальная часть исследований выполнена на 48 беспородных собаках. Было проведено 5 серий экспериментов. Проведен анализ морфологического и функционального состояния усовершенствованных вариантов сосудистых анасто- мозов в ближайшем и отдаленном периодах после операции. Результаты и их обсуждение Разработаны 2 новых способа микрохирургических органосохраняющих спленоренальных анастомозов и способ мезентерикоренального анастомоза. Получены новые данные о динамике заживления сосудистых анастомозов на различных сроках после реконструктивных операций, изучены их морфологические и функциональные ха- рактеристики. Выводы Результаты исследования показывают, что применение микрохирургической техники в сочетании с наружным каркасом из деминерализованной трубчатой кости позволяет создавать портокавальные анастомозы с сохранением поч- ки и селезенки, обеспечивать хорошее функционирование анастомозов без применения антикоагулянтов.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>Portal hypertension</kwd><kwd>microsurgery</kwd><kwd>vascular anastomosis</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>1. Eramishantsev A.K. 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