Journal of Experimental and Clinical SurgeryJournal of Experimental and Clinical SurgeryВестник экспериментальной и клинической хирургии2070-478X2409-143XVoronezh State Medical University named after N.N. Burdenko32110.18499/2070-478X-2011-4-4-848-854Original articlesОригинальные статьиUnknownThe role of mast cells in wound healingК вопросу о роли тучных клеток в процессе заживления ранАлексееваН.Т.

Алексеева Наталия Тимофеевна – к.м.н., доц. ка- федры нормальной анатомии человека Воронеж- ской государственной медицинской академии им. Н.Н.Бурденко; e-mail: alexeevant@list.ru

author@vestnik-surgery.comГлуховА.А.

Глухов Александр Анатольевич – д.м.н., проф., заведующий кафедрой общей хирургии, дирек- тор НИИ хирургической инфекции Воронеж- ской государственной медицинской академии им. Н.Н.Бурденко; e-mail: surgery-v@ya.ru

author@vestnik-surgery.comВоронежская государственная медицинская академия им. Н.Н.Бурденко24122011448488542904201629042016Copyright ©; 2011, Voronezh N.N. Burdenko State Medical UniversityCopyright ©; 2011, ФГБОУ ВО ВГМУ им. Н.Н. Бурденко Минздрава России2011Voronezh N.N. Burdenko State Medical UniversityФГБОУ ВО ВГМУ им. Н.Н. Бурденко Минздрава Россииhttps://vestnik-surgery.com/journal/about/editorialPolicieshttps://vestnik-surgery.com/journal/article/view/321

Восстановительные реакции в течение раневого процесса показывают, что тучные клетки проходят сложнейшую внутреннюю морфофункциональную эволюцию, оказывая строго специфические координированные влияния на ход заживления. Процесс дегрануляции тучных клеток и последующая стимуляция неоангиогенеза могут рассматриваться как составная часть компенсаторно-приспособительной реакции тканей при раневом процессе. Полученная информация позволяет проводить корреляции между различными видами клеток, в зависимости от их участия в различных стадиях раневого процесса. Только глубокий структурно-функциональный анализ клеточных и внутриклеточных изменений среди всех компонентов поврежденной ткани позволяет понять механизмы восстановления, составляющие морфологический эквивалент региональной терапии

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