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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="other" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Journal of Experimental and Clinical Surgery</journal-id><journal-title-group><journal-title xml:lang="en">Journal of Experimental and Clinical Surgery</journal-title><trans-title-group xml:lang="ru"><trans-title>Вестник экспериментальной и клинической хирургии</trans-title></trans-title-group></journal-title-group><issn publication-format="print">2070-478X</issn><issn publication-format="electronic">2409-143X</issn><publisher><publisher-name xml:lang="en">Voronezh State Medical University named after N.N. Burdenko</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">328</article-id><article-id pub-id-type="doi">10.18499/2070-478X-2009-2-2-168-172</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Original articles</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Оригинальные статьи</subject></subj-group><subj-group subj-group-type="article-type"><subject>Unknown</subject></subj-group></article-categories><title-group><article-title xml:lang="en">The new approach and principles early instillation of diagnosis general forms of infection and mesenchymal sepsis</article-title><trans-title-group xml:lang="ru"><trans-title>Новые подходы и принципы ранней диагностики генерализованных форм инфекции и мезенхимального сепсиса</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name><surname>Бархатова</surname><given-names>H.А.</given-names></name><bio xml:lang="ru"><p>кандидат медицинских наук, ассистент кафедры общей хирургии Челябинской государственной медицинской академии.</p></bio><email>mmfz@incompany.ru</email><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">Chelyabinsk State Medical Academy</institution></aff><aff><institution xml:lang="ru">Челябинская государственная медицинская академия</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2009-06-24" publication-format="electronic"><day>24</day><month>06</month><year>2009</year></pub-date><volume>2</volume><issue>2</issue><issue-title xml:lang="ru"/><fpage>168</fpage><lpage>172</lpage><history><date date-type="received" iso-8601-date="2016-04-30"><day>30</day><month>04</month><year>2016</year></date><date date-type="accepted" iso-8601-date="2016-04-30"><day>30</day><month>04</month><year>2016</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2009, .</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2009, Бархатова H.</copyright-statement><copyright-year>2009</copyright-year><copyright-holder xml:lang="en">.</copyright-holder><copyright-holder xml:lang="ru">Бархатова H.</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">http://creativecommons.org/licenses/by-nc-nd/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://vestnik-surgery.com/journal/article/view/328">https://vestnik-surgery.com/journal/article/view/328</self-uri><abstract xml:lang="en"><p>To carry out analysis results of treatment 2250 patients with differents forms infection of soft tissues. Combination of clinic of system inflammatory reaction to moderate augmentation C-reactive protein over 30 mg/l, olygopeptides more 0,34 unit, lactoferrin over 1900 ng/ml, breach balance of cytokines with prevailing TNF in combination with conservation systemic inflammatory response syndrome more 72 hourses after the equivalent operation and beginning conservative treatment.</p></abstract><trans-abstract xml:lang="ru"><p>Проведено проспективное исследование результатов лечения 2250 больных с различными гнойно-некротическими заболеваниями мягких тканей. Сочетание клиники системной воспалительной реакции с умеренным увеличением С-реактивного белка (12-29 мг/л), олигопептидов (менее 0,34 ед.), лактоферрина крови (менее 1900 нг/мл) и дисба- лансом уровня цитокинов в пользу противовоспалительного ИЛ-1РА указывает на высокую вероятность купирова- ния данного синдрома в первые 72 часа.</p></trans-abstract><kwd-group xml:lang="en"><kwd>early diagnostics</kwd><kwd>a generalised infection</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>ранняя диагностика</kwd><kwd>генерализованная инфекция</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>1. Eriukhin I.A. Infektsiia v khirurgii. Staraia problema na</mixed-citation></ref><ref id="B2"><label>2.</label><mixed-citation>kanune novogo tysiacheletiia.[The old problem on the eve of the new millennium.] Ch.1. Vest. khirurgii 1998;157: 1: 85-91.</mixed-citation></ref><ref id="B3"><label>3.</label><mixed-citation>2. 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