<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE root>
<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="other" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Journal of Experimental and Clinical Surgery</journal-id><journal-title-group><journal-title xml:lang="en">Journal of Experimental and Clinical Surgery</journal-title><trans-title-group xml:lang="ru"><trans-title>Вестник экспериментальной и клинической хирургии</trans-title></trans-title-group></journal-title-group><issn publication-format="print">2070-478X</issn><issn publication-format="electronic">2409-143X</issn><publisher><publisher-name xml:lang="en">Voronezh State Medical University named after N.N. Burdenko</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">354</article-id><article-id pub-id-type="doi">10.18499/2070-478X-2011-4-2-283-288</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Original articles</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Оригинальные статьи</subject></subj-group><subj-group subj-group-type="article-type"><subject>Unknown</subject></subj-group></article-categories><title-group><article-title xml:lang="en">The light and ultrastructural analysis duodenal mucosa in chronic pancreatitis</article-title><trans-title-group xml:lang="ru"><trans-title>Светооптический и ультраструктурный анализ слизистой оболочки двенадцатиперстной кишки при хроническом панкреатите</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name><surname>Вискунов</surname><given-names>В.Г</given-names></name><bio><p>к.м.н., врач-хирург городской поликлиники №18 г. Новосибирска</p></bio><email>svetlana-procenko@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name><surname>Проценко</surname><given-names>С.И</given-names></name><bio><p>д.м.н., профес- сор кафедры хирургических болезней ФПК и ППВ Новосибирского государственного медицинского университета</p></bio><email>Vladimir.Viskunov@yadex.ru</email><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">Новосибирский государственный медицинский университет&#13;
НИИ региональной патологии и патоморфологии СО РАМН, г. Новосибирск</institution></aff><aff><institution xml:lang="ru">Новосибирский государственный медицинский университет НИИ региональной патологии и патоморфологии СО РАМН, г. Новосибирск</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2011-06-24" publication-format="electronic"><day>24</day><month>06</month><year>2011</year></pub-date><volume>4</volume><issue>2</issue><issue-title xml:lang="ru"/><fpage>283</fpage><lpage>288</lpage><history><date date-type="received" iso-8601-date="2016-04-30"><day>30</day><month>04</month><year>2016</year></date><date date-type="accepted" iso-8601-date="2016-04-30"><day>30</day><month>04</month><year>2016</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2011, ., .</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2011, Вискунов В., Проценко С.</copyright-statement><copyright-year>2011</copyright-year><copyright-holder xml:lang="en">., .</copyright-holder><copyright-holder xml:lang="ru">Вискунов В., Проценко С.</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">http://creativecommons.org/licenses/by-nc-nd/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://vestnik-surgery.com/journal/article/view/354">https://vestnik-surgery.com/journal/article/view/354</self-uri><abstract xml:lang="en"><p>By light and electron microscopy, investigated the mucosa of the duodenum in patients with chronic pancreatitis. It was found in light-optical investigation of samples of the duodenum a signifi cant stereotype of structural rearrangements of the mucous membrane. These included the general characteristics of pathological changes: diffuse dystrophy of the intestinal epithelium, disturbance of the structure and function of Brunner's gland, multiple sclerosis, and lymphoplasmacytic infi ltration of the lamina propria. Ultrastructure of the epithelium of the duodenum included the expansion of intercellular spaces, the deformation of microvilli, degradation of cytoplasmic organelles, the appearance of large lysosomes and mielopodobnyh formation, which refl ects the violation of transport and metabolic processes in the enterocytes.</p></abstract><trans-abstract xml:lang="ru"><p>Методами световой и электронной микроскопии исследовали слизистую оболочку двенадцатиперстной кишки у больных с хроническим панкреатитом. При светооптическом исследовании образцов двенадцатиперстной кишки выявлена значительная стереотипность структурных перестроек слизистой оболочки, включающих: диффузную дистрофию кишечного эпителия, нарушение структуры и функции бруннеровых желез, склероз и лимфоплазмоци- тарную инфильтрацию собственной пластинки. Ультраструктура эпителия двенадцатиперстной кишки включала расширение межклеточных пространств, деформацию микроворсинок, деструкцию цитоплазматических органелл, появление крупных лизосом и миелоподобных образований, что отражало нарушение транспортных и метаболиче- ских процессов в энтероцитах.</p></trans-abstract><kwd-group xml:lang="en"><kwd>duodenum</kwd><kwd>enterocytes</kwd><kwd>chronic pancreatitis (parenchymal and duktalny)</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>двенадцатиперстная кишка</kwd><kwd>энтероциты</kwd><kwd>хронический панкреатит (паренхиматозный и дуктальный)</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>1. Datsenko B.M., Martynenko F.P. Klassifikatsiia khro-</mixed-citation></ref><ref id="B2"><label>2.</label><mixed-citation>nicheskogo pankreatita. Khirurgiia 1984; 2: 101-103.</mixed-citation></ref><ref id="B3"><label>3.</label><mixed-citation>2. Lopatkina T.N. Khronicheskii pankreatit. Novyi me-</mixed-citation></ref><ref id="B4"><label>4.</label><mixed-citation>ditsinskii zhurnal 1997; 2: 7-11.</mixed-citation></ref><ref id="B5"><label>5.</label><mixed-citation>3. Lutsevich E.V., Cheplenko G.V. Podzheludochnaia zheleza kak</mixed-citation></ref><ref id="B6"><label>6.</label><mixed-citation>odna iz mishenei «autofermentnogo vzryva» pri pan-</mixed-citation></ref><ref id="B7"><label>7.</label><mixed-citation>kreatite. Khirurgiia 2001; 9: 57-60.</mixed-citation></ref><ref id="B8"><label>8.</label><mixed-citation>4. Khazanov A.I., Vasil'ev A.P., Spesivtsev V.N., Loginov</mixed-citation></ref><ref id="B9"><label>9.</label><mixed-citation>A.F. Khronicheskii pankreatit, ego techenie i iskhody.</mixed-citation></ref><ref id="B10"><label>10.</label><mixed-citation>Ros. zhurnal gastroenterol., gepatol., koloproktol</mixed-citation></ref><ref id="B11"><label>11.</label><mixed-citation>1999; 4: 24-25.</mixed-citation></ref><ref id="B12"><label>12.</label><mixed-citation>5. Shalimov A.A., Grubnik V.V., Gorovits Dzh. i dr. Khroni-</mixed-citation></ref><ref id="B13"><label>13.</label><mixed-citation>cheskii pankreatit. Kiev, Izd-vo Zdorov'e 2000; 255.</mixed-citation></ref><ref id="B14"><label>14.</label><mixed-citation>6. Beger H.G., Buchler H.W., Distshuneit H. Chronic</mixed-citation></ref><ref id="B15"><label>15.</label><mixed-citation>pancreatitis. Berlin 1990; 148.</mixed-citation></ref><ref id="B16"><label>16.</label><mixed-citation>7. Spiro H.M. Clinicalgastroenterogy. M. Graw. Hill Inc.</mixed-citation></ref><ref id="B17"><label>17.</label><mixed-citation>1994; 1297.</mixed-citation></ref><ref id="B18"><label>18.</label><mixed-citation>8. Steer M.L., Waxman I., Freedman S. Chronic pancreatitis.</mixed-citation></ref><ref id="B19"><label>19.</label><mixed-citation>Eng. J. Med.1995; 332: 1482-1490.</mixed-citation></ref></ref-list></back></article>
