Journal of Experimental and Clinical SurgeryJournal of Experimental and Clinical SurgeryВестник экспериментальной и клинической хирургии2070-478X2409-143XVoronezh State Medical University named after N.N. Burdenko3610.18499/2070-478X-2015-8-3-256-262Original articlesОригинальные статьиUnknownFeatures of a Clinical Current and Diagnostics of Acute Pancreatitis at Patients with Virus HepatitisОсобенности клинического течения и диагностики острого панкреатита у больных вирусным гепатитомЗемлянойВ.П.

VD, Prof., head of the Department of faculty surgery named after I.I. Grekov, North-Western state medical University named after I. I. Mechnikov, Ministry of Health of the Russian Federation

д.м.н., проф., зав. кафедрой факуль-тетской хирургии им. И.И. Грекова

mail@vestnik-surgery.comСингаевскийA.Б.

 MD, prof. of the Department of faculty surgery named after I.I. Grekov, same university

д.м.н., проф. кафедры факуль-тетской хирургии им. И.И. Грекова

mail@vestnik-surgery.comСидоровР.С.

 PhD, assistant professor of the Department of faculty surgery named after I.I. Grekov, same university

к.м.н., ассистент кафедры факуль-тетской хирургии им. И.И. Грекова

mail@vestnik-surgery.comЛабазановВ.M.

surgeon at St-Petersburg Botkin Clinical Infectious Diseases Hospital

The purpose of the study To study peculiarities of the clinical course, diagnosis and treatment outcomes of acute pancreatitis in patients with viral hepatitis. 

Materials and methods The study is based on an analysis of 133 cases of acute pancreatitis. Of these 82 patients with acute pancreatitis have viral hepatitis and 51 patient developed acute pancreatitis without concomitant viral hepatitis. 

Results and their discussion Septic complications of destructive forms of acute pancreatitis was significantly more frequently encountered in patients with concomitant viral hepatitis (in 15 patients of the study group (18.3%) and two patients of the control group (3.9%)). Bacteremia was registered in 9 patients of the study group (10,9%). There were no cases of bacteremia in a control group. The incidence of liver failure in patients with a combination of acute pancreatitis and viral hepatitis was significantly higher than among patients of the control group (24,3% and 1.9% respectively). 

Conclusions Our study demonstrated a high incidence of septic complications of acute pancreatitis in patients with viral hepatitis. It was found that the presence of viral hepatitis in patients with acute pancreatitis is an adverse prognostic factor contributing to the high incidence of septic complications and mortality

врач-хирург хирургического от-деления

mail@vestnik-surgery.comI.I. Mechnikov North-Western State Medical University, 41 Kirochnaia Str., Saint-Petersburg, 191015, Russian FederationСеверо-Западный государственный медицинский университет им. И.И. Мечникова, ул. Кирочная, д. 41, Санкт-Петербург, 191015, Российская ФедерацияI.I. Mechnikov North-Western State Medical University, 41 Kirochnaia Str., Saint-Petersburg, 191015, Russian FederationСанкт-Петербургская Клиническая инфекционная больница им. С.П.Боткина.24092015832562622504201625042016Copyright ©; 2015, ., ., ., .Copyright ©; 2015, Земляной В., Сингаевский A., Сидоров Р., Лабазанов В.2015., ., ., .Земляной В., Сингаевский A., Сидоров Р., Лабазанов В.http://creativecommons.org/licenses/by-nc-nd/4.0https://vestnik-surgery.com/journal/article/view/36

The purpose of the study To study peculiarities of the clinical course, diagnosis and treatment outcomes of acute pancreatitis in patients with viral hepatitis. 

Materials and methods The study is based on an analysis of 133 cases of acute pancreatitis. Of these 82 patients with acute pancreatitis have viral hepatitis and 51 patient developed acute pancreatitis without concomitant viral hepatitis. 

Results and their discussion Septic complications of destructive forms of acute pancreatitis was significantly more frequently encountered in patients with concomitant viral hepatitis (in 15 patients of the study group (18.3%) and two patients of the control group (3.9%)). Bacteremia was registered in 9 patients of the study group (10,9%). There were no cases of bacteremia in a control group. The incidence of liver failure in patients with a combination of acute pancreatitis and viral hepatitis was significantly higher than among patients of the control group (24,3% and 1.9% respectively). 

Conclusions Our study demonstrated a high incidence of septic complications of acute pancreatitis in patients with viral hepatitis. It was found that the presence of viral hepatitis in patients with acute pancreatitis is an adverse prognostic factor contributing to the high incidence of septic complications and mortality

Цель исследования Изучить особенности клинического течения, диагностики и исходов лечения острого панкреатита убольных вирусным гепатитом.Материалы и методы В основу работы положен анализ течения острого панкреатита у 133 больных. Из них в 82 случаяхострый панкреатит развивался на фоне вирусного гепатита, в 51 наблюдениях – без сопутствующего вирусного гепати-та.Результаты и их обсуждение Септические осложнения деструктивных форм острого панкреатита достоверно чащевстречались у больных с сопутствующим вирусным гепатитом ‑ у 15 пациентов основной группы (18,3%) и двух больныхконтрольной (3,9%). Случаев бактериемии у больных основной группы было 9 (10,9%). В контрольной группе случаев бакте-риемии выявлено не было. Частота развития печеночной недостаточности у больных с сочетанием острого панкреатитаи вирусного гепатита (24,3%) достоверно превышала аналогичные показатели у больных контрольной группы (1,9%).Выводы В ходе проведенного исследования были получены данные, указывающие на высокую частоту развития гнойныхосложнений острого панкреатита у больных вирусным гепатитом. Установлено, что наличие вирусного гепатита у боль-ных острым панкреатитом является неблагоприятным прогностическим фактором, обусловливающим высокую частотугнойно-септических осложнений и летальность.

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