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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="other" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Journal of Experimental and Clinical Surgery</journal-id><journal-title-group><journal-title xml:lang="en">Journal of Experimental and Clinical Surgery</journal-title><trans-title-group xml:lang="ru"><trans-title>Вестник экспериментальной и клинической хирургии</trans-title></trans-title-group></journal-title-group><issn publication-format="print">2070-478X</issn><issn publication-format="electronic">2409-143X</issn><publisher><publisher-name xml:lang="en">Voronezh State Medical University named after N.N. Burdenko</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">378</article-id><article-id pub-id-type="doi">10.18499/2070-478X-2011-4-2-344-348</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Original articles</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Оригинальные статьи</subject></subj-group><subj-group subj-group-type="article-type"><subject>Unknown</subject></subj-group></article-categories><title-group><article-title xml:lang="en">Modeling of chronic osteomyelitis</article-title><trans-title-group xml:lang="ru"><trans-title>Моделирование хронического остеомиелита</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name><surname>Ладонин</surname><given-names>С.В.</given-names></name><bio><p>соискатель кафе- дры общей хирургии Самарского государственного медицинского университета</p></bio><email>ladonina.n@yandex.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name><surname>Сонис</surname><given-names>А.Г.</given-names></name><bio><p>к.м.н., доцент ка- федры общей хирургии, декан лечебного факуль- тета Самарского государственного медицинского университета</p></bio><email>ladonina.n@yandex.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name><surname>Алексеев</surname><given-names>Д.Г.</given-names></name><bio><p>к.м.н., ассистент кафедры общей хирургии Самарского государ- ственного медицинского университета</p></bio><email>ladonina.n@yandex.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name><surname>Белозерцева</surname><given-names>E.A.</given-names></name><bio><p>к.м.н., старший научный сотрудник Института экспери- ментальной медицины и биологии Самарского государственного медицинского университета</p></bio><email>ladonina.n@yandex.ru</email><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><name><surname>Вовк</surname><given-names>E.A.</given-names></name><bio xml:lang="en"><p>аспирант кафедры общей хирургии Самарского государственного медицинского университета</p></bio><bio xml:lang="ru"><p>аспирант кафе- дры общей хирургии Самарского государственного медицинского университета</p></bio><email>ladonina.n@yandex.ru</email><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff id="aff1"><institution>Самарский государственный медицинский университет</institution></aff><aff-alternatives id="aff2"><aff><institution xml:lang="en">Самарский государственный медицинский университета</institution></aff><aff><institution xml:lang="ru">Самарский государственный медицинский университет</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2011-06-24" publication-format="electronic"><day>24</day><month>06</month><year>2011</year></pub-date><volume>4</volume><issue>2</issue><issue-title xml:lang="ru"/><fpage>344</fpage><lpage>348</lpage><history><date date-type="received" iso-8601-date="2016-04-30"><day>30</day><month>04</month><year>2016</year></date><date date-type="accepted" iso-8601-date="2016-04-30"><day>30</day><month>04</month><year>2016</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2011, ., ., ., ., .</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2011, Ладонин С., Сонис А., Алексеев Д., Белозерцева E., Вовк E.</copyright-statement><copyright-year>2011</copyright-year><copyright-holder xml:lang="en">., ., ., ., .</copyright-holder><copyright-holder xml:lang="ru">Ладонин С., Сонис А., Алексеев Д., Белозерцева E., Вовк E.</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">http://creativecommons.org/licenses/by-nc-nd/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://vestnik-surgery.com/journal/article/view/378">https://vestnik-surgery.com/journal/article/view/378</self-uri><abstract xml:lang="en"><p>The results of experimental study of chronic osteomyelitis modifi ed model’s development are represented. Research was performed in 16 purebred rabbits. Inspectional, radiological and morphological monitoring of process was used. We observe uprising of chronic osteomyelitis in 14 days of experiment. Developed model of osteomyelitis causes pathological process in 100% of cases, yields quite a large focus of bone destruction, and gives possibility to develop the new methods of bone cavities reconstruction.</p></abstract><trans-abstract xml:lang="ru"><p>Представлены результаты экспериментального исследования по разработке модификации модели хронического остеомиелита. Исследование выполнено на 16 беспородных кроликах. Проводилось визуальное, рентгенологиче- ское, морфологическое мониторирование процесса. Развитие хронического остеомиелита наблюдалось к 14 суткам эксперимента. Разработанная модель вызывает патологический процесс в 100% случаев, позволяет получить очаг костной деструкции достаточно больших размеров, дает возможность разрабатывать новые способы остеопластики.</p></trans-abstract><kwd-group xml:lang="en"><kwd>сhronic osteomyelitis</kwd><kwd>experimental model of osteomyelitis</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>хронический остеомиелит</kwd><kwd>экспериментальная модель остеомиелита</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>1. Amiraslanov Iu.A., Svetukhin A.M., Borisov I.V., Usha-</mixed-citation></ref><ref id="B2"><label>2.</label><mixed-citation>kov A.A. Khirurgicheskoe lechenie bol'nykh s osteomie-</mixed-citation></ref><ref id="B3"><label>3.</label><mixed-citation>litom dlinnykh kostei. Mat. 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