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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="other" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Journal of Experimental and Clinical Surgery</journal-id><journal-title-group><journal-title xml:lang="en">Journal of Experimental and Clinical Surgery</journal-title><trans-title-group xml:lang="ru"><trans-title>Вестник экспериментальной и клинической хирургии</trans-title></trans-title-group></journal-title-group><issn publication-format="print">2070-478X</issn><issn publication-format="electronic">2409-143X</issn><publisher><publisher-name xml:lang="en">Voronezh State Medical University named after N.N. Burdenko</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">534</article-id><article-id pub-id-type="doi">10.18499/2070-478X-2014-7-3-181-189</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Original articles</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Оригинальные статьи</subject></subj-group><subj-group subj-group-type="article-type"><subject>Unknown</subject></subj-group></article-categories><title-group><article-title xml:lang="en">Features of Angioarchitectonics and Hemodynamics in the System of the Portal Vein in Patients with Cirrhosis of the Liver with Portal Hypertension</article-title><trans-title-group xml:lang="ru"><trans-title>Особенности ангиоархитектоники и гемодинамики в системе воротной вены у больных циррозом печени с портальной гипертензией</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name><surname>Назыров</surname><given-names>Ф.Г</given-names></name><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>M.D., Prof.,, director of Republican Specialized Center of Surgery named after acad. V.Vakhidov (RSCS). head of department of surgery of the liver, biliary tract, pancreatoduodenal zone and portal hypertension, Honored Worker of Health of the Republic of Uzbekistan, the vice-president of the Association of Surgeons, hepatologists of CIS, Academician of RANS</p></bio><bio xml:lang="ru"><p>д.м.н., проф., дирек- тор Республиканского Специализированного Цен- тра Хирургии (РСЦХ) им. академика В. Вахидова, руководитель отдела хирургии печени, желчных путей, панкреатодуоденальной зоны и портальной гипертензии, заслуженный работник здравоохра- нения Республики Узбекистан, вице-президент Ас- социации хирургов-гепатологов стран СНГ, Акаде- мик РАЕН</p></bio><email>cs.75@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name><surname>Девятов</surname><given-names>A.B.</given-names></name><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>M.D., Prof., chief researcher of the department of surgery of portal hypertension and pancreatoduodenal zone of RSCS</p></bio><bio xml:lang="ru"><p>д.м.н., проф., глав- ный научный сотрудник отделения хирургии пор- тальной гипертензии и панкреатодуоденальной зоны РСЦХ им. академика В. Вахидова</p></bio><email>cs.75@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name><surname>Бабаджанов</surname><given-names>A.Х.</given-names></name><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Ph.D., senior research fellow of the department of surgery of portal hypertension and pancreatoduodenal zone of RSCS</p></bio><bio xml:lang="ru"><p>к.м.н., ст. научный сотрудник отделения хирургии портальной гипер- тензии и панкреатодуоденальной зоны РСЦХ им. академика В. Вахидова</p></bio><email>azam746@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name><surname>Байбеков</surname><given-names>И.М.</given-names></name><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>doctoral candidate of the department of the surgery of portal hypertension and pancreatoduodenal zone of RSCS</p></bio><bio xml:lang="ru"><p>д.м.н., профес- сор, руководитель отделения патологической ана- томии РСЦХ им. академика В. Вахидова,</p></bio><email>cs.75@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name><surname>Раимов</surname><given-names>С.A.</given-names></name><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>M.D., Prof., head of the department of pathological anatomy of RSCS</p></bio><bio xml:lang="ru"><p>к.м.н., доктор- ант отделения хирургии портальной гипертензии и панкреатодуоденальной зоны РСЦХ им. академика В. Вахидова;</p></bio><email>cs.75@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">Republican Specialized Center of Surgery named after acad. V.Vahidov, 10 Farkhadskaia Str., Tashkent, &#13;
700115, Uzbekistan</institution></aff><aff><institution xml:lang="ru">Республиканский Специализированный Центр Хирургии им. академика В. Вахидова, ул. Фархадская, д. 10, Ташкент, 700115, Узбекистан</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2014-09-24" publication-format="electronic"><day>24</day><month>09</month><year>2014</year></pub-date><volume>7</volume><issue>3</issue><issue-title xml:lang="ru"/><fpage>181</fpage><lpage>189</lpage><history><date date-type="received" iso-8601-date="2016-05-04"><day>04</day><month>05</month><year>2016</year></date><date date-type="accepted" iso-8601-date="2016-05-04"><day>04</day><month>05</month><year>2016</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2014, Voronezh N.N. Burdenko State Medical University</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2014, ФГБОУ ВО ВГМУ им. Н.Н. Бурденко Минздрава России</copyright-statement><copyright-year>2014</copyright-year><copyright-holder xml:lang="en">Voronezh N.N. Burdenko State Medical University</copyright-holder><copyright-holder xml:lang="ru">ФГБОУ ВО ВГМУ им. Н.Н. Бурденко Минздрава России</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://vestnik-surgery.com/journal/about/editorialPolicies</ali:license_ref></license></permissions><self-uri xlink:href="https://vestnik-surgery.com/journal/article/view/534">https://vestnik-surgery.com/journal/article/view/534</self-uri><abstract xml:lang="en"><p>Relevance In surgery of portal hypertension (PH), special importance is attached to the variants of anatomy of the vessels of splenoportal and left renal pools which have fundamental importance in terms of the possibility of imposing different types of shunt operations. The purpose of the study To study features of angioarchitectonics and hemodynamics in the system of portal vein in patients with liver cirrhosis (LC) with portal hypertension. Materials and methods For identifying features of changes of angioarchitectonics of portal pool in the conditions of progressive PH were examined 254 patients with liver cirrhosis, which from 2007 to 2013 were performed different variants of the vascular portosystemic shunt. All patients were divided into three age groups: under 30 years; 31-49 years and older than 50 years. Results and their discussion In the older age group, the development and progression of PH does not lead to a significant increasing the size of the spleen. Conversely, in the group of 30 years spleen size had a tendency to form splenomegaly 2-3 degrees. Facticaly in equivalent level of portal pressure, diameters of v.portae and v.lienalis had significant difference. In the group of under 30 years portal vein diameter was 1,45 ± 0,03 cm in the group 31-49 years - 1,37 ± 0,02 cm, and in the group older than 50 years was the lowest diameter - 1,30 ± 0, 03 cm, and splenic 1,05 ± 0,04 cm. In comparing the diameter of the splenic vein in all of the parameter to receives significant difference with the formation of a minimum diameter - 1,05 ± 0,04 cm in patients older than 50 years. Conclusion Compensation of progressive PH due to expansion of the vascular channel of splenoportal pool is most common in patients with liver cirrhosis under 30 years, which proves maximum angiotransformation with a significant relative to the other age groups increasing of diameter of v.portae and v.lienalis, severity of splenomegaly and a lower incidence of variceal bleeding carried over. Conducted morphological studies have shown that in the conditions of liver cirrhosis with portal hypertension, the structure of the walls of veins of portolienal pool undergoes substantial changes, severity of which depends on the age of the patients and for patients older than 50 years is characterized by a more pronounced thickening of membranes, especially t. media and t. adventitia, and for patients under 30 years - increasing the lumen of the veins</p></abstract><trans-abstract xml:lang="ru"><p>Актуальность В хирургии портальной гипертензии (ПГ) особое значение отводится вариантной анатомии сосудов спленопортального и левого ренального бассейнов, имеющей принципиальное значение в плане возможности наложения различного типа шунтирующих операций. Цель исследования Изучить особенности ангиоархитектоники и гемодинамики в системе воротной вены у больных циррозом печени (ЦП) с портальной гипертензией. Материалы и методы Для выявления этих особенностей было обследовано 254 больных ЦП, которым с 2007 по 2013 гг были выполнены различные варианты сосудистого портосистемного шунтирования. Все больные разделены на три воз- растные группы: до 30 лет; 31-49 лет и старше 50 лет. Результаты и их обсуждение В старшей возрастной группе развитие и прогрессирование ПГ не приводит к значитель- ному увеличению размеров селезенки. Наоборот, в группе до 30 лет размеры селезенки имели тенденцию к формированию спленомегалии 2-3 степени. При фактически равноценном уровне портального давления диаметры v.portae и v.lienalis имели существенную разницу. В группе до 30 лет диаметр портальной вены составил 1,45±0,03 см, в группе 31-49 лет - 1,37±0,02 см, в группе старше 50 лет диаметр оказался наименьшим - 1,30±0,03 см, а селезёночной – 1,05±0,04 см. При сравнении диаметра селезеночной вены по всем сопоставляемым параметрам получено достоверное отличие с формиро- ванием минимального диаметра - 1,05±0,04 см в группе больных старше 50 лет. Выводы Компенсация прогрессирующей ПГ за счет расширения сосудистого русла спленопортального бассейна наиболее характерна для пациентов с ЦП до 30 лет, что доказывает максимальная ангиотрансформация с достоверным по отно- шению к другим возрастным группам увеличением диаметра v.portae и v.lienalis, выраженности спленомегалии и меньшая частота перенесенных кровотечений из ВРВПЖ. Проведенные морфологические исследования показали, что в условиях ЦП с ПГ структура стенок вен портолиенального бассейна претерпевает существенные изменения, выраженность ко- торых зависит от возраста больных и для пациентов старше 50 лет характеризуется более выраженным утолщением оболочек, особенно t. media и t. аdventitia, а для пациентов до 30 лет - увеличением просвета вен.</p></trans-abstract><kwd-group xml:lang="en"><kwd>Liver cirrhosis</kwd><kwd>portal hypertension</kwd><kwd>portosystemic shunt</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>Цирроз печени</kwd><kwd>портальная гипертензия</kwd><kwd>портосистемное шунтирование</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>1. Barber K., Madden S., Allen J. et al. 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