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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="other" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Journal of Experimental and Clinical Surgery</journal-id><journal-title-group><journal-title xml:lang="en">Journal of Experimental and Clinical Surgery</journal-title><trans-title-group xml:lang="ru"><trans-title>Вестник экспериментальной и клинической хирургии</trans-title></trans-title-group></journal-title-group><issn publication-format="print">2070-478X</issn><issn publication-format="electronic">2409-143X</issn><publisher><publisher-name xml:lang="en">Voronezh State Medical University named after N.N. Burdenko</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">668</article-id><article-id pub-id-type="doi">10.18499/2070-478X-2011-4-3-440-445</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Original articles</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Оригинальные статьи</subject></subj-group><subj-group subj-group-type="article-type"><subject>Unknown</subject></subj-group></article-categories><title-group><article-title xml:lang="en">Citokines profi le features for patients with postoperative ventral hernias at the using of the endoprosthesis "Ecofl on" and "Unifl eks"</article-title><trans-title-group xml:lang="ru"><trans-title>Особенности цитокинового профиля у больных с послеоперационными вентральными грыжами при использовании эндопротезов «Экофлон» и «Унифлекс»</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name><surname>Иванов</surname><given-names>С.В.</given-names></name><address><country country="RU">Russian Federation</country></address><bio xml:lang="ru"><p>Иванов Сергей Викторович – д.м.н., профессор, за- ведующий кафедрой хирургических болезней №1 Курского государственного медицинского университета;</p></bio><email>ivanov.is@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name><surname>Лазаренко</surname><given-names>В.A.</given-names></name><address><country country="RU">Russian Federation</country></address><bio xml:lang="ru"><p>д.м.н., профес- сор, заведующий кафедрой хирургии ФПО, ректор Курского государственного медицинского универ- ситета</p></bio><email>ivanov.is@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name><surname>Иванов</surname><given-names>И.С.</given-names></name><address><country country="RU">Russian Federation</country></address><bio xml:lang="ru"><p>– к.м.н., доцент кафедры хирургических болезней №1 Курского государ- ственного медицинского университета</p></bio><email>ivanov.is@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name><surname>Kатунина</surname><given-names>T.П.</given-names></name><address><country country="RU">Russian Federation</country></address><bio xml:lang="ru"><p>Катунина Татьяна Петровна – аспирант кафедры хирургических болезней №1 Курского государ- ственного медицинского университета</p></bio><email>ivanov.is@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name><surname>Цуканов</surname><given-names>A.В.</given-names></name><address><country country="RU">Russian Federation</country></address><bio xml:lang="ru"><p>Цуканов Андрей Викторович – ассистент кафе- дры хирургических болезней №1 Курского госу- дарственного медицинского университета</p></bio><email>ivanov.is@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en"></institution></aff><aff><institution xml:lang="ru">Курский государственный медицинский университет</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2011-09-24" publication-format="electronic"><day>24</day><month>09</month><year>2011</year></pub-date><volume>4</volume><issue>3</issue><issue-title xml:lang="ru"/><fpage>440</fpage><lpage>445</lpage><history><date date-type="received" iso-8601-date="2016-05-18"><day>18</day><month>05</month><year>2016</year></date><date date-type="accepted" iso-8601-date="2016-05-18"><day>18</day><month>05</month><year>2016</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2011, ., ., ., ., .</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2011, Иванов С., Лазаренко В., Иванов И., Kатунина T., Цуканов A.</copyright-statement><copyright-year>2011</copyright-year><copyright-holder xml:lang="en">., ., ., ., .</copyright-holder><copyright-holder xml:lang="ru">Иванов С., Лазаренко В., Иванов И., Kатунина T., Цуканов A.</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">http://creativecommons.org/licenses/by-nc-nd/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://vestnik-surgery.com/journal/article/view/668">https://vestnik-surgery.com/journal/article/view/668</self-uri><abstract xml:lang="en"><p>Surgical treatment of abdominal wall hernia is the very important problem of modern surgery. Up to 15-35% of all the «open» operations on abdominal wall lead to postoperative ventral hernias formation and their complications. The further research of endoprosthesis implantation area condition, especially cytokine profi le in dynamics, is necessary. The immunologic reactivity of different in structure, thickness, hardness and, what is more important, chemical structure of endoprosthesis is still not studied. The results of politeraftoretilen – «Ecofl on» (71 patients) and polyvinilidenftoride «PVDF-Unifl ex» (41 patients) endoprosthesis clinical use have been studied. The research of cytokine profi le in the postoperative period to determine the implants biocompatibility was hold.</p></abstract><trans-abstract xml:lang="ru"><p>Хирургическое лечение грыж передней брюшной стенки является очень важной проблемой современной хирур- гии. До 15-35% открытых операций на брюшной стенке приводит к образованию послеоперационных вентральных грыж и их осложнений. Необходимо дальнейшее изучение состояния области имплантации эндопротеза, особенно цитокинового профиля в динамике. Не изученным остается вопрос об иммунологической реактивности различных по структуре, толщине, жесткости и самое главное химической структуре эндопротезов. Исследованы результаты клинического применения эндопротезов из полипропилена - «Экофлон» (71 пациент) и поливинилиденфторида – «Унифлекс» (41 пациент). Проведено изучение цитокинового профиля в послеоперационном периоде для определе- ния биосовместимости протезов.</p></trans-abstract><kwd-group xml:lang="en"><kwd>postoperative ventral hernia</kwd><kwd>endoprosthesis replacement</kwd><kwd>cytokine profi le</kwd><kwd>immune reactivity endoprosthesis</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>: послеоперационная вентральная грыжа</kwd><kwd>эндопротезирование</kwd><kwd>цитокиновый профиль</kwd><kwd>иммунологическая реактивность эндопротезов</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>1. Belokonev V.I., Pushkin S.Iu., Fedorina T.A. [Biomekha-</mixed-citation></ref><ref id="B2"><label>2.</label><mixed-citation>nicheskaia kontseptsiia patogeneza posleoperatsionnykh</mixed-citation></ref><ref id="B3"><label>3.</label><mixed-citation>ventral'nykh gryzh. Vestn. khirurgii im. I.I. 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