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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="other" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Journal of Experimental and Clinical Surgery</journal-id><journal-title-group><journal-title xml:lang="en">Journal of Experimental and Clinical Surgery</journal-title><trans-title-group xml:lang="ru"><trans-title>Вестник экспериментальной и клинической хирургии</trans-title></trans-title-group></journal-title-group><issn publication-format="print">2070-478X</issn><issn publication-format="electronic">2409-143X</issn><publisher><publisher-name xml:lang="en">Voronezh State Medical University named after N.N. Burdenko</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">669</article-id><article-id pub-id-type="doi">10.18499/2070-478X-2011-4-3-528-531</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Original articles</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Оригинальные статьи</subject></subj-group><subj-group subj-group-type="article-type"><subject>Unknown</subject></subj-group></article-categories><title-group><article-title xml:lang="en">Features of immune status at newborns with necrotizing enterocolitis</article-title><trans-title-group xml:lang="ru"><trans-title>Особенности клеточного и гуморального иммунитета у новорожденных с язвенно-некротическим энтероколитом</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name><surname>Kaрпова</surname><given-names>И.Ю.</given-names></name><address><country country="RU">Russian Federation</country></address><bio xml:lang="ru"><p>Карпова Ирина Юрьевна – к.м.н., ассистент ка- федры детской хирургии Нижегородской го- сударственной медицинской академии</p></bio><email>ikarpova73@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name><surname>Паршиков</surname><given-names>В.В.</given-names></name><address><country country="RU">Russian Federation</country></address><bio xml:lang="ru"><p>Паршиков Вячеслав Владимирович – д.м.н., про- фессор, заведующий кафедрой детской хирургии Нижегородской государственной медицинской академии;</p></bio><email>ped-surg@gma.nnov.ru</email><xref ref-type="aff" rid="aff2"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en"></institution></aff><aff><institution xml:lang="ru">Нижегородская государственная медицинская академия</institution></aff></aff-alternatives><aff-alternatives id="aff2"><aff><institution xml:lang="en"></institution></aff><aff><institution xml:lang="ru">Городская клиническая больница №1, Нижний Новгород</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2011-09-24" publication-format="electronic"><day>24</day><month>09</month><year>2011</year></pub-date><volume>4</volume><issue>3</issue><issue-title xml:lang="ru"/><fpage>528</fpage><lpage>531</lpage><history><date date-type="received" iso-8601-date="2016-05-18"><day>18</day><month>05</month><year>2016</year></date><date date-type="accepted" iso-8601-date="2016-05-18"><day>18</day><month>05</month><year>2016</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2011, Voronezh N.N. Burdenko State Medical University</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2011, ФГБОУ ВО ВГМУ им. Н.Н. Бурденко Минздрава России</copyright-statement><copyright-year>2011</copyright-year><copyright-holder xml:lang="en">Voronezh N.N. Burdenko State Medical University</copyright-holder><copyright-holder xml:lang="ru">ФГБОУ ВО ВГМУ им. Н.Н. Бурденко Минздрава России</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://vestnik-surgery.com/journal/about/editorialPolicies</ali:license_ref></license></permissions><self-uri xlink:href="https://vestnik-surgery.com/journal/article/view/669">https://vestnik-surgery.com/journal/article/view/669</self-uri><abstract xml:lang="en"><p>80 newborns with necrotizing enterocolitis were observed from2006 – 2009 in Nizhniy Novgorod Children's Municipal Clinical Hospital No 1. The research of parameters cellular and humoral immunity is executed 40 (50%) patients. The negative infl uence on formation immune system was rendered by harmful habits of the parents, sharp and chronic diseases of the mothers, intrauterine infection, chronic hypoxia, complication during childbirth. The parameters immunograms of the patients with necrotizing enterocolitis refl ect a clinical picture of disease, but are not specifi c, therefore can be additional diagnostic criterion of forecasting infl ammatory process.</p></abstract><trans-abstract xml:lang="ru"><p>В детской городской больнице № 1 с 2006 по 2009 гг. наблюдалось 80 больных с язвенно-некротическим энтероко- литом (ЯНЭК). Исследование показателей клеточного и гуморального иммунитета выполнено 40 (50%) больным. Негативное воздействие на формирование иммунной системы оказывали вредные привычки родителей, острые и хронические заболевания матерей, внутриутробное инфицирование плода, хроническая гипоксия, осложнения во время родов. Показатели иммунограмм пациентов с ЯНЭК отражают клиническую картину заболевания, но не яв- ляются специфичными, поэтому могут являться дополнительным диагностическим критерием прогнозирования воспалительного процесса.</p></trans-abstract><kwd-group xml:lang="en"><kwd>newborn</kwd><kwd>necrotizing enterocolitis</kwd><kwd>immunit</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>новорожденный</kwd><kwd>язвенно-некротический энтероколит</kwd><kwd>иммунитет</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>1. Narogan M.E. Zashchita bezzashchitnykh. Osobennosti</mixed-citation></ref><ref id="B2"><label>2.</label><mixed-citation>immuniteta novorozhdennykh. «9 mesiatsev» 2009; 2:</mixed-citation></ref><ref id="B3"><label>3.</label><mixed-citation>21-23.</mixed-citation></ref><ref id="B4"><label>4.</label><mixed-citation>2. Red'ko I.I. Kliniko-metabolicheskie osobennosti</mixed-citation></ref><ref id="B5"><label>5.</label><mixed-citation>techeniia khlamidiinoi infektsii u novorozhdennykh</mixed-citation></ref><ref id="B6"><label>6.</label><mixed-citation>detei. Rossiiskii vestnik perinatologii i pedia-</mixed-citation></ref><ref id="B7"><label>7.</label><mixed-citation>trii 1998; 3 – 15 .</mixed-citation></ref><ref id="B8"><label>8.</label><mixed-citation>3. Strunina I.G. Infektsionno-vospalitel'nye za-</mixed-citation></ref><ref id="B9"><label>9.</label><mixed-citation>bolevaniia materi kak faktor riska perinatal'noi</mixed-citation></ref><ref id="B10"><label>10.</label><mixed-citation>patologii: Avtoref. dis. ... kand. med. nauk. M.</mixed-citation></ref><ref id="B11"><label>11.</label><mixed-citation>1993; 24.</mixed-citation></ref><ref id="B12"><label>12.</label><mixed-citation>4. Nepokul'chitskaia N.V., Dolgina E.N., Samsygina G.A.</mixed-citation></ref><ref id="B13"><label>13.</label><mixed-citation>Immunologicheskaia kharakteristika detei pervykh</mixed-citation></ref><ref id="B14"><label>14.</label><mixed-citation>trekh mesiatsev zhizni s vnutriutrobnoi i postna-</mixed-citation></ref><ref id="B15"><label>15.</label><mixed-citation>tal'noi infektsiei. Pediatriia 1994; 7: 23-26.</mixed-citation></ref><ref id="B16"><label>16.</label><mixed-citation>5. Samsygina G.A., Buslaeva G.N., Nepokul'chitskaia</mixed-citation></ref><ref id="B17"><label>17.</label><mixed-citation>N.V. Gematologicheskaia i immunologicheskaia kharak-</mixed-citation></ref><ref id="B18"><label>18.</label><mixed-citation>teristika vnutriutrobnykh infektsii u detei. Pe-</mixed-citation></ref><ref id="B19"><label>19.</label><mixed-citation>diatriia 1997; 4: 59-62. Nepokul'chitskaia N.V. Kharakteristika nekotorykh</mixed-citation></ref><ref id="B20"><label>20.</label><mixed-citation>pokazatelei immunnogo reagirovaniia u detei s</mixed-citation></ref><ref id="B21"><label>21.</label><mixed-citation>vnutriutrobnoi i postnatal'noi infektsiei:</mixed-citation></ref><ref id="B22"><label>22.</label><mixed-citation>avtoref. dis. … kand. med. nauk. M 1995; 24.</mixed-citation></ref><ref id="B23"><label>23.</label><mixed-citation>7. Levitskaia E.B. Kriterii prognozirovaniia vnutri-</mixed-citation></ref><ref id="B24"><label>24.</label><mixed-citation>utrobnykh i postnatal'nykh infektsii u novorozh-</mixed-citation></ref><ref id="B25"><label>25.</label><mixed-citation>dennykh detei materei s infektsionnoi patologiei:</mixed-citation></ref><ref id="B26"><label>26.</label><mixed-citation>avtoref. dis. … kand. med. nauk. Kiev 1985; 24.</mixed-citation></ref></ref-list></back></article>
