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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="other" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Journal of Experimental and Clinical Surgery</journal-id><journal-title-group><journal-title xml:lang="en">Journal of Experimental and Clinical Surgery</journal-title><trans-title-group xml:lang="ru"><trans-title>Вестник экспериментальной и клинической хирургии</trans-title></trans-title-group></journal-title-group><issn publication-format="print">2070-478X</issn><issn publication-format="electronic">2409-143X</issn><publisher><publisher-name xml:lang="en">Voronezh State Medical University named after N.N. Burdenko</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">82</article-id><article-id pub-id-type="doi">10.18499/2070-478X-2014-7-2-132-140</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Original articles</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Оригинальные статьи</subject></subj-group><subj-group subj-group-type="article-type"><subject>Unknown</subject></subj-group></article-categories><title-group><article-title xml:lang="en">Integraned Palliative Treatment Tumors of Esophagus, Cardia and Esophageal Anastomosis</article-title><trans-title-group xml:lang="ru"><trans-title>Комплексное паллиативное лечение при опухолевом поражении пищевода, кардии и пищеводных анастомозов</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name><surname>Дробязгин</surname><given-names>Е.А.</given-names></name><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>MD, docent of department hospital and children surgery Novosibirsk State medical university, thoracic surgeon, endoscopist department of thoracic surgery Novosibirsk State Regional clinical hospital</p></bio><bio xml:lang="ru"><p>д.м.н., доц. кафедры госпитальной и детской хирургии Новосибирского государственного медицинского университета, врач торакальный хирург, эндоскопист отделения торакальной хирургии Государственной Новосибирской областной клинической больницы</p></bio><email>author@vestnik-surgery.com</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name><surname>Чикинев</surname><given-names>Ю.В.</given-names></name><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>MD, Professor, head of department hospital and children surgery Novosibirsk State medical university, thoracic surgeon department of thoracic surgery Novosibirsk State Regional clinical hospital</p></bio><bio xml:lang="ru"><p>д.м.н., зав. кафедрой госпитальной хирургии Новосибирского государственного медицинского университета</p></bio><email>author@vestnik-surgery.com</email><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><name><surname>Аникеева</surname><given-names>О.Ю.</given-names></name><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>PhD, head of the department of radiotherapy Novosibirsk Research Institute of Circulation Pathology</p></bio><bio xml:lang="ru"><p>к.м.н., зав. отделением радиотерапии Новосибирского научно-исследовательского института патологии кровообращения имени академика Е.Н. Мешалкина</p></bio><email>author@vestnik-surgery.com</email><xref ref-type="aff" rid="aff3"/></contrib><contrib contrib-type="author"><name><surname>Кудрявцев</surname><given-names>А.С.</given-names></name><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>oncolog, thoracic surgeon of the department of radiotherapy Novosibirsk Research Institute of Circulation Pathology</p></bio><bio xml:lang="ru"><p>врач онколог, торакальный хирург Новосибирского научно-исследовательского института патологии кровообращения имени академика Е.Н.Мешалкина</p></bio><email>author@vestnik-surgery.com</email><xref ref-type="aff" rid="aff4"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">Novosibirsk State Medical University, 52 Krasnyi Ave., Novosibirsk, 630091, Russian Federation</institution></aff><aff><institution xml:lang="ru">Новосибирский государственный медицинский университет, Красный пр-т, д. 52, Новосибирск, 630091, Российская Федерация</institution></aff></aff-alternatives><aff-alternatives id="aff2"><aff><institution xml:lang="en">Novosibirsk State Regional Clinical Hospital, 130 Nemirovicha-Danchenko Str., Novosibirsk, 630087, &#13;
Russian Federation</institution></aff><aff><institution xml:lang="ru">Государственная Новосибирская областная клиническая больница, ул. Немировича-Данченко, д. 130, Новосибирск, 630087, Российская Федерация</institution></aff></aff-alternatives><aff-alternatives id="aff3"><aff><institution xml:lang="en">Novosibirsk Research Institute of Circulation Pathology, 15 Rechkunovskaia Str., Novosibirsk, 630055, Russian Federation</institution></aff><aff><institution xml:lang="ru">Новосибирский научно-исследовательский институт патологии кровообращения им. академика Е.Н. Мешалкина, ул. Речкуновская, д. 15, Новосибирск, 630055, Российская Федерация</institution></aff></aff-alternatives><aff-alternatives id="aff4"><aff><institution xml:lang="en">Novosibirsk Research Institute of Circulation Pathology, 15 Rechkunovskaia Str., Novosibirsk, 630055, Russian Federation3</institution></aff><aff><institution xml:lang="ru">Новосибирский научно-исследовательский институт патологии кровообращения им. академика Е.Н. Мешалкина, ул. Речкуновская, д. 15, Новосибирск, 630055, Российская Федерация</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2014-06-24" publication-format="electronic"><day>24</day><month>06</month><year>2014</year></pub-date><volume>7</volume><issue>2</issue><issue-title xml:lang="ru"/><fpage>132</fpage><lpage>140</lpage><history><date date-type="received" iso-8601-date="2016-04-26"><day>26</day><month>04</month><year>2016</year></date><date date-type="accepted" iso-8601-date="2016-04-26"><day>26</day><month>04</month><year>2016</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2014, ., ., ., .</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2014, Дробязгин Е., Чикинев Ю., Аникеева О., Кудрявцев А.</copyright-statement><copyright-year>2014</copyright-year><copyright-holder xml:lang="en">., ., ., .</copyright-holder><copyright-holder xml:lang="ru">Дробязгин Е., Чикинев Ю., Аникеева О., Кудрявцев А.</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">http://creativecommons.org/licenses/by-nc-nd/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://vestnik-surgery.com/journal/article/view/82">https://vestnik-surgery.com/journal/article/view/82</self-uri><abstract xml:lang="en"><p>Relevance Marked increase in the incidence of malignant neoplasms of the esophagus and cardia. By the time of diagnosis, more than 50 % of patients can not perform radical surgery because of the severity of the patient or the local prevalence of neoplastic lesions. The purpose of the study To assess the results of palliative interventions in malignant tumors of the esophagus, cardia and oesophageal anastomosis. Materials and methods Stenting of the esophagus and esophageal anastomoses performed 133 patients (99 men and 34 women). The age of patients ranged from 35 to 91 years . Esophageal cancer was in 80 patients, cancer of the gastric cardia involving esophagus in 33, compression of the esophagus from the outside in 5, recurrent gastric cancer after gastrectomy in 8, recurrence of esophageal cancer after surgery type Lewis at 4 esophageal cancer recurrence after extirpation of the esophagus with gastroplasty at 3. Stenting was performed silicone stents in 22 patients and nitinol partially or fully covered stents in 111 patients. Results and their discussion Complications of stent placement were observed in 9 patients (2 with silicone stents and 7 using nitinol stents). Complications after stenting were 21 patients (8 - silicone stents, 13 - self-expanding stents ). All complications promptly diagnosed and corrected. Stenting the stent -in- stent were 11 patients in the period from 2 to 14 months after stenting. Deaths were observed. Conclusion Endoscopic stenting of the esophagus and esophageal anastomosis is an effective and safe method of restoring oral ingestion. Preferably self-expanding stents used metal . Performing esophageal stenting prior to radical radiation therapy allows for treatment without splitting rate, with a low risk of esophageal stenosis under irradiation without increasing percentage radioreactions.</p></abstract><trans-abstract xml:lang="ru"><p>Актуальность Отмечается увеличение заболеваемости злокачественными новообразованиями пищевода и кардии. К моменту установления диагноза более 50% пациентов невозможно выполнить радикальное хирургическое вмешательство из-за тяжести состояния пациента или местной распространенности опухолевого поражения. Цель исследования Оценка результатов паллиативных вмешательств при злокачественных новообразованиях пищевода, кардии и пищеводных анастомозов. Материалы и методы Стентирование пищевода и пищеводных анастомозов выполнено 133 пациентам (99 мужчин и 34 женщины). Возраст пациентов составил от 35 лет до 91 года. Рак пищевода был у 80 пациентов, рак кардиального отдела желудка с переходом на пищевод у 33, сдавление пищевода извне у 5, рецидив рака желудка после гастрэктомии у 8, рецидив рака пищевода после операции типа Lewis у 4, рецидив рака пищевода после экстирпации пищевода с эзофагогастропластикой у 3. Стентирование осуществлялось силиконовыми стентами у 22 пациентов и нитиноловыми частично или полностью покрытыми стентами у 111 пациентов. Результаты и их обсуждение Осложнения при установке стентов отмечены у 9 пациентов (2 при использовании силиконовых стентов и 7 при использовании нитиноловых). Осложнения после стентирования были у 21 пациента (8 – силиконовые стенты, 13 – саморасправляющиеся стенты). Все осложнения своевременно диагностированы и устранены. Стентирование стент-в-стент проведено 11 пациентам в сроки от 2 до 14 месяцев после стентирования. Летальных исходов не отмечено. Выводы Эндоскопическое стентирование пищевода и пищеводных анастомозов является эффективным и безопасным методом восстановления перорального приема пищи. Предпочтительно использовать металлические саморасправляющиеся стенты. Выполнение пищеводного стентирования перед проведением радикального курса лучевой терапии позволяет провести лечение без расщепления курса, с низким риском стеноза пищевода при облучении, не увеличивая процент лучевых реакций.</p></trans-abstract><kwd-group xml:lang="en"><kwd>cancer of the esophagus</kwd><kwd>esophageal stenting</kwd><kwd>self-expanding metal stents</kwd><kwd>conformal radiation therapy</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>рак пищевода</kwd><kwd>стентирование пищевода</kwd><kwd>саморасправляющиеся стенты</kwd><kwd>конформная лучевая терапия</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>1. Gallinger Yu. I., Godzhello E. A., Khrustaleva M. V., Amelina M. A. Pervyj opyt primeneniya samoraspravlyayushchihsya metallicheskih stentov pri inkurabel'nyh porazheniyah pishchevoda i pishchevodnyh anastomozov. Tezisy XII Moskovskogo mezhdunarodnogo Kongressa po ehndoskopicheskoj hirurgii, [the First experience of application of self-expanding metal stents with incurable lesions of the esophagus and esophageal anastomosis. Abstracts of the XII Moscow international Congress on endoscopic surgery,] 2008; 108-111.</mixed-citation></ref><ref id="B2"><label>2.</label><mixed-citation>2. Gaudiello, E. A., Khrustaleva M. V., Gallinger Yu. I., Permyakov V. B. Vybor sposoba ehndoskopicheskogo protezirovaniya opuholevyh porazhenij pishchevoda, kardii i pishchevodnyh anastomozov cameraspanasonic stenty. Vestnik hirurgicheskoj gastroehnterologii.[the choice of the method of endoscopic prosthesis neoplastic lesions of the esophagus, cardia and esophageal anastomosis cameraspanasonic the stents. Bulletin of surgical gastroenterology.] 2011; 2: 14-26.</mixed-citation></ref><ref id="B3"><label>3.</label><mixed-citation>3. In Sokolov.In. EHndoprotezirovanie pri zlokachestvennoj strikture pishchevoda i kardii. Klinicheskie tekhnologii.[Endoprosthesis for malignant stricture of the esophagus and cardia. Clinical technology.] 2007; 1: 16.</mixed-citation></ref><ref id="B4"><label>4.</label><mixed-citation>4. In The Passing Game.In., Zubova N. D., E Ivolgin.M. Pozdnie luchevye povrezhdeniya organov grudnoj kletki. Sibirskij onkologicheskij zhurnal. [Late radiation injuries of the chest. Siberian oncological journal.] 2009; 6(36): 58-61.</mixed-citation></ref><ref id="B5"><label>5.</label><mixed-citation>5. In Chissov.And. Onkologiya: nacional'noe rukovodstvo. [Oncology: national leadership.] M.: GEOTAR-Media. 2008; 128-168</mixed-citation></ref><ref id="B6"><label>6.</label><mixed-citation>6. A. Balazs, Kokas P., P. Lukovich, Kupcsulik P. Palliativnoe lechenie zlokachestvennyh striktur pishchevoda stentirovanie s 25-letnim stazhem. [Palliative treatment of malignant strictures of the esophagus stent implantation with 25 years of experience.] Magy SEB. 2011; 64(6): 267-276</mixed-citation></ref><ref id="B7"><label>7.</label><mixed-citation>7. Bergquist G., Wenger, W., Johnson, E. et al. Stentirovaniya ili vnutriprosvetnoj brahiterapii v kachestve palliativnogo lecheniya bol'nyh rakom pishchevoda i pishchevodno-zheludochnogo perekhoda. Rezul'taty randomizirovannyh kontroliruemyh klinicheskih issledovanij. [Stent insertion or endoluminal brachytherapy as palliation of patients with cancer of the esophagus and gastroesophageal junction. The results of randomized controlled clinical studies.] Dis. Esophagus 2005; 18: 131-139.</mixed-citation></ref><ref id="B8"><label>8.</label><mixed-citation>8. Bernhard Berger, Claus Belka et al. Dokazatel'naya radiacionnaya Onkologiya: rak pishchevoda, luchevaya terapiya i Onkologiya [Evidence-based radiation Oncology: esophageal cancer radiotherapy and Oncology] 92. 2009; 276-290</mixed-citation></ref><ref id="B9"><label>9.</label><mixed-citation>9. Bjerring O. S. T. Pless K. Fristrup, M. B. Mortensen. priemlemye rezul'taty posle selfexpanding metallicheskih stentov dlya lecheniya disfagii v neoperabel'nyh raka pishchevoda. [acceptable results after selfexpanding metal stent for treatment of dysphagia in non-resectable cancer of the esophagus.] Dan. Med. J. 2012; 59: 4459.</mixed-citation></ref><ref id="B10"><label>10.</label><mixed-citation>10. A. Dubecz, T. J. Watson., Raymond D. P., Jones C., A. Matousek, J. Allen., Salvador, R., Polomsky, M., Peters, I. N. stentirovanie pishchevoda pri zlokachestvennyh i dobrokachestvennyh zabolevanij: 133 dela po torakal'noj hirurgicheskoj sluzhby. [esophageal stenting for malignant and benign disease: 133 cases on a thoracic surgical service.] Ann. TCD. Surg. 2011; 92(6): 2028-2032</mixed-citation></ref><ref id="B11"><label>11.</label><mixed-citation>11. And Eickhoff, D. Hartmann, R. Jacobs, U. Weickert, D. Schilling, J. Eickhoff, K., Riemann, J. F. sravnenie 3 vidov ohvatyvaemyh samoraspravlyayushchihsya metallicheskih stentov dlya palliativnogo lecheniya zlokachestvennoj disfagii: rezul'taty prospektivnogo Lyudvigskhafen pishchevoda rakovogo registra. [comparison of 3 types of covered self-expanding metal stents for palliation of malignant dysphagia: results from the prospective Ludwigshafen esophageal cancer register.] Z.</mixed-citation></ref><ref id="B12"><label>12.</label><mixed-citation>Gastroenterol. 2005; 43(10): 1113-1121.</mixed-citation></ref><ref id="B13"><label>13.</label><mixed-citation>12. Ferrante M., Feliziani M., Imperatori, A., Ferrari L. Bernasconi G. EHndoskopicheskoe palliativnoe lechenie raka pishchevoda luchej[Endoscopic palliation of esophageal cancer rays].. . 2006; 31(1): 3-7.</mixed-citation></ref><ref id="B14"><label>14.</label><mixed-citation>13. Freeman R. K., Ascioti, A., Mahidhara, R. J. Palliativnoe lechenie PA-vydelyaetsya pri neoperabel'nom rake pishchevoda. [Palliative treatment of PA-allocated for inoperable carcinoma of the esophagus.] Surg. Wedge. North. J. 2012; 92(5): 1337-1351.</mixed-citation></ref><ref id="B15"><label>15.</label><mixed-citation>14. Konosu M., Kimura, Y., Iwaya, T., Akiyama, Y., Fujiwara H., Endo F., Sugitachi A., Nishizuka, S., Nitta H., Otsuka K., Kashiwaba, M., Koeda, A., K. Sasaki, M. Mizuno, G. Poleznost' stentirovanie pishchevoda dlya fistuly esophagorespiratory s rakom pishchevoda. Wakabayashi, [the Usefulness of esophageal stenting for esophagorespiratory fistula with esophageal cancer.] Gan To The Team, Ryoho. 2012; 39(12): 1849-1851.</mixed-citation></ref><ref id="B16"><label>16.</label><mixed-citation>15. C. Mariette, G. Piessen, J. P. Triboulet,terapevticheskie strategii pri rake pishchevoda: rol' hirurgii i drugih metodov. [therapeutic strategies in oesophageal cancer: role of surgery and other methods.] Lancet Oncol. 2007; 8: 545-553.</mixed-citation></ref><ref id="B17"><label>17.</label><mixed-citation>16. Martinez J., Rice, M. M., Quiros, R. M. stentirovanie pishchevoda pri ustanovlenii zlokachestvennosti. [esophageal stenting in the setting of malignancy.] ISRN Gastroenterol. 2011; 719575.</mixed-citation></ref><ref id="B18"><label>18.</label><mixed-citation>17. Massey S. rak pishchevoda i palliativnoe lechenie disfagii. [esophageal cancer and palliation of dysphagia.] Wedge. John. Oncol. Nursi. 2011; 15(3): 327-329.</mixed-citation></ref><ref id="B19"><label>19.</label><mixed-citation>18. Mergener K., Kozarek, R. A. Stentirovanie zheludochno-kishechnogo trakta [Stenting of the gastrointestinal tract..] dig. Dis. 2002; 20(2): 173-181.</mixed-citation></ref><ref id="B20"><label>20.</label><mixed-citation>19. Motilall R. S., Modiba, M. S., Tsatsi, L. D., Becker P. I. Probnaya versiya</mixed-citation></ref><ref id="B21"><label>21.</label><mixed-citation>samoraspravlyayushchihsya metallicheskih stentov v palliativnogo lecheniya tracheooesophageal svishcha v rak pishchevoda [the trial version</mixed-citation></ref><ref id="B22"><label>22.</label><mixed-citation>self-expanding metal stents in the palliative treatment of tracheooesophageal fistula in carcinoma of the esophagus..] S. AFR. J. Surg. 2007, ; 45(1): 24-27.</mixed-citation></ref><ref id="B23"><label>23.</label><mixed-citation>20. Mougey, A., Adler D. G. pishchevodnyh stentov dlya palliativnogo lecheniya zlokachestvennoj disfagii [esophageal stenting for palliation of malignant dysphagia..] support John. Onkol'., 2008; 6(6): 267-273.</mixed-citation></ref><ref id="B24"><label>24.</label><mixed-citation>21. Nathwani, R. A., Kowalski T. EHndoskopicheskoe stentirovanie raka pishchevoda: klinicheskie posledstviya.. [Endoscopic stenting of esophageal cancer: clinical implications..] Resp. OPIN. Gastroenterol. 2007; 23(5): 535-538.</mixed-citation></ref><ref id="B25"><label>25.</label><mixed-citation>22. Rueth, N. M., Shaw, D., Cunha, J., Cho S., M. A. Maddaus, R. S. Andrade stentirovanie pishchevoda i radioterapii: mul'timodal'nyj podhod dlya lecheniya simptomaticheskoj zlokachestvennoj disfagii.[Andrade esophageal stenting and radiotherapy: a multimodal approach for palliation of symptomatic malignant dysphagia.] Ann. Surg. Onkol'., 2012; 19(13): 4223-4228.</mixed-citation></ref><ref id="B26"><label>26.</label><mixed-citation>23. Seitz J., Giovannini M, Padaut-Cesana J. et al. Nonmetastatic neoperabel'nym ploskokletochnym rakom pishchevoda v vedenii soputstvuyushchej himioterapii (5-ftoruracila i cisplatina) i luchevoj terapii. Rak, [Inoperable Nonmetastatic squamous cell carcinoma of the esophagus run by concomitant chemotherapy (5-fluorouracil and cisplatin) and radiation therapy. Cancer,] 1990; 66: 214-219.</mixed-citation></ref></ref-list></back></article>
