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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="research-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Journal of Experimental and Clinical Surgery</journal-id><journal-title-group><journal-title xml:lang="en">Journal of Experimental and Clinical Surgery</journal-title><trans-title-group xml:lang="ru"><trans-title>Вестник экспериментальной и клинической хирургии</trans-title></trans-title-group></journal-title-group><issn publication-format="print">2070-478X</issn><issn publication-format="electronic">2409-143X</issn><publisher><publisher-name xml:lang="en">Voronezh State Medical University named after N.N. Burdenko</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">936</article-id><article-id pub-id-type="doi">10.18499/2070-478X-2012-5-1-51-53</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Original articles</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Оригинальные статьи</subject></subj-group><subj-group subj-group-type="article-type"><subject>Research Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">Acute perforated ulcers of the small intestine in patients with total purulent peritonitis</article-title><trans-title-group xml:lang="ru"><trans-title>Острые перфоративные язвы тонкой кишки у больных с распространенным гнойным перитонитом</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Gol'brajh</surname><given-names>Vyacheslav Arkad'evich</given-names></name><name xml:lang="ru"><surname>Гольбрайх</surname><given-names>Вячеслав Аркадьевич</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Doctor of Medical Sciences, Professor of the Department of Hospital Surgery of the Volgograd State Medical University</p></bio><bio xml:lang="ru"><p>доктор медицинских наук, профессор кафедры госпитальной хирургии Волгоградского государственого медицинского университета</p></bio><email>maskins@bk.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Maskin</surname><given-names>Sergej Sergeevich</given-names></name><name xml:lang="ru"><surname>Маскин</surname><given-names>Сергей Сергеевич</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Doctor of Medical Sciences, Head of the Department of Hospital Surgery of the Volgograd State Medical University</p></bio><bio xml:lang="ru"><p>доктор медицинских наук, заведующий кафедрой госпитальной хирургии Волгоградского государственного медицинского университета</p></bio><email>maskins@bk.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Bobyrin</surname><given-names>Aleksandr Vladimirovich</given-names></name><name xml:lang="ru"><surname>Бобырин</surname><given-names>Александр Владимирович</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Honored Doctor of the Russian Federation, Head of Surgery Department No. 2 Hospital Surgical Clinic of the Volgograd State Medical University</p></bio><bio xml:lang="ru"><p>заслуженный врач РФ, заведующий хирургическим отделением №2госпитальной хирургической клиники Волгоградского государственого медицинского университета</p></bio><email>maskins@bk.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Karsanov</surname><given-names>Alan Muharbekovich</given-names></name><name xml:lang="ru"><surname>Карсанов</surname><given-names>Алан Мухарбекович</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Candidate of Medical Science, doctoral student of the Department of Hospital Surgery of the Volgograd State Medical University</p></bio><bio xml:lang="ru"><p>кандидат медицинских наук, докторант кафедры госпитальной хирургии Волгоградского государственого медицинского университета </p></bio><email>maskins@bk.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Derbenceva</surname><given-names>Tat'yana Viktorovna</given-names></name><name xml:lang="ru"><surname>Дербенцева</surname><given-names>Татьяна Викторовна</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Post-graduate student of the Department of Hospital Surgery of the Volgograd State Medical University</p></bio><bio xml:lang="ru"><p>аспирант кафедры госпитальной хирургии Волгоградского государственого медицинского университета</p></bio><email>maskins@bk.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Lopastejskij</surname><given-names>Denis Sergeevich</given-names></name><name xml:lang="ru"><surname>Лопастейский</surname><given-names>Денис Сергеевич</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Candidate of Medical Science, Assistant of the Department of Hospital Surgery of the Volgograd State Medical University</p></bio><bio xml:lang="ru"><p>кандидат медицинских наук, ассистент кафедры госпитальной хирургии Волгоградского государственого медицинского университета</p></bio><email>denlopas76@yandex.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Tadzhieva</surname><given-names>Ajgul' Rahmonkulovna</given-names></name><name xml:lang="ru"><surname>Таджиева</surname><given-names>Айгуль Рахмонкуловна</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Post-graduate student of the Department of Hospital Surgery of the Volgograd State Medical University</p></bio><bio xml:lang="ru"><p>аспирант кафедры госпитальной хирургии Волгоградского государственого медицинского университета</p></bio><email>maskins@bk.ru</email><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">Volgograd State Medical University</institution></aff><aff><institution xml:lang="ru">Волгоградский государственный медицинский университет</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2012-01-19" publication-format="electronic"><day>19</day><month>01</month><year>2012</year></pub-date><volume>5</volume><issue>1</issue><issue-title xml:lang="ru"/><fpage>51</fpage><lpage>53</lpage><history><date date-type="received" iso-8601-date="2017-03-09"><day>09</day><month>03</month><year>2017</year></date><date date-type="accepted" iso-8601-date="2017-03-10"><day>10</day><month>03</month><year>2017</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2012, Voronezh N.N. Burdenko State Medical University</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2012, ФГБОУ ВО ВГМУ им. Н.Н. Бурденко Минздрава России</copyright-statement><copyright-year>2012</copyright-year><copyright-holder xml:lang="en">Voronezh N.N. Burdenko State Medical University</copyright-holder><copyright-holder xml:lang="ru">ФГБОУ ВО ВГМУ им. Н.Н. Бурденко Минздрава России</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/" start_date="2017-11-19"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://vestnik-surgery.com/journal/about/editorialPolicies</ali:license_ref></license></permissions><self-uri xlink:href="https://vestnik-surgery.com/journal/article/view/936">https://vestnik-surgery.com/journal/article/view/936</self-uri><abstract xml:lang="en"><p>Modern views on etiology, pathogenesis of acute ulcers of the small intestine (AUSI) complicated by perforation werepresented. Purulent total peritonitis (PTP) is one of the reasons of acute stress-ulcers beginning. Perforation of AUSI in thisgroup was diagnosed in 16 (3,2%) patients. By the example of patients with PTP, the risk-factors of AUSI formation weredetermined: high level of the Mannheim peritonitis index (more 15), long-term nose-intestinal intubation, prolonged artificiallung ventilation and enteroparesis in postoperative period. For prophylaxis of AUSI elimination of circulatory hypoxia,enteroparesis, endotoxicosis are demanded.</p></abstract><trans-abstract xml:lang="ru"><p>В работе представлены современные взгляды на этиологию и патогенез острых язв тонкой кишки (ОЯТК), осложненных перфорацией. Одной из причин возникновения острых стресс-язв является распространенный гнойныйперитонит (РГП). Из 493 больных, оперированных по поводу РГП, перфорация острых язв тонкой кишки диагностирована у 16 пациентов (3,2%). Определены факторы риска возникновения послеоперационных язв тонкой кишки:высокий Мангеймский индекс перитонита (выше 15), длительное назоинтестинальное дренирование, продолжительная ИВЛ и парез кишечника после операции. Профилактика ОЯТК должна включать ликвидацию циркуляторной гипоксии, пареза кишечника, эндотоксикоза.</p></trans-abstract><kwd-group xml:lang="en"><kwd>acute ulcers of the small intestine, purulent peritonitis, programmed relaparotomy</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>стресс-язвы тонкой кишки, гнойный перитонит, программированная релапаротомия</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>1. Gel'fand B.R., Gur'yanov V.A., Mamontova O.A. Profilaktika Stressovykh povrezhdeniy zheludka u patsiyentov v neotlozhnom sostoyanii.Ifections v khirurgii.[Prophylactics of stress damages of a stomach in patients in urgent state. 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