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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="research-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Journal of Experimental and Clinical Surgery</journal-id><journal-title-group><journal-title xml:lang="en">Journal of Experimental and Clinical Surgery</journal-title><trans-title-group xml:lang="ru"><trans-title>Вестник экспериментальной и клинической хирургии</trans-title></trans-title-group></journal-title-group><issn publication-format="print">2070-478X</issn><issn publication-format="electronic">2409-143X</issn><publisher><publisher-name xml:lang="en">Voronezh State Medical University named after N.N. Burdenko</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">990</article-id><article-id pub-id-type="doi">10.18499/2070-478X-2012-5-1-154-159</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Original articles</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Оригинальные статьи</subject></subj-group><subj-group subj-group-type="article-type"><subject>Research Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">The use of early enteral nutrition and selective decontamination of the intestine in the treatment of acute destructive pancreatitis</article-title><trans-title-group xml:lang="ru"><trans-title>Применение раннего энтерального питания и селективной деконтаминации кишечника в лечении острого деструктивного панкреатита</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Mylnikov</surname><given-names>Andrey Gennadievich</given-names></name><name xml:lang="ru"><surname>Мыльников</surname><given-names>Андрей Геннадьевич</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Candidate of Medical Sciences, Associate Professor of the Scientific and Educational Center of Abdominal Surgery and Endoscopy of the Russian State Medical Univernity named after N. N. Pirogov</p></bio><bio xml:lang="ru"><p>кандидат медицинских наук, доцент научно-образовательного центра абдоминальной хирургии и эндоскопии Российского государственного медицнского униерситета имени Н.Н.Пирогова</p></bio><email>dr.mylnikov@yandex.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Korolev</surname><given-names>Sergey Vladimirovich</given-names></name><name xml:lang="ru"><surname>Королев</surname><given-names>Сергей Владимирович</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Junior research assistant of the Institute of Surgery named after A.V. Vishnevsky</p></bio><bio xml:lang="ru"><p>младший научный сотрудник Института хирургии имени А.В. Вишневского</p></bio><email>Korolev-S@ixv.comcor.ru</email><xref ref-type="aff" rid="aff2"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">Russian State Medical University named after N.I. Pirogov</institution></aff><aff><institution xml:lang="ru">Российский государственный медицинский университет имени Н.Н.Пирогова</institution></aff></aff-alternatives><aff-alternatives id="aff2"><aff><institution xml:lang="en">Institute of Surgery named after A.V. Vishnevsky</institution></aff><aff><institution xml:lang="ru">Институт хирургии имени А.В.Вишневского</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2012-01-19" publication-format="electronic"><day>19</day><month>01</month><year>2012</year></pub-date><volume>5</volume><issue>1</issue><issue-title xml:lang="ru"/><fpage>154</fpage><lpage>159</lpage><history><date date-type="received" iso-8601-date="2017-03-14"><day>14</day><month>03</month><year>2017</year></date><date date-type="accepted" iso-8601-date="2017-04-02"><day>02</day><month>04</month><year>2017</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2012, Voronezh N.N. Burdenko State Medical University</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2012, ФГБОУ ВО ВГМУ им. Н.Н. Бурденко Минздрава России</copyright-statement><copyright-year>2012</copyright-year><copyright-holder xml:lang="en">Voronezh N.N. Burdenko State Medical University</copyright-holder><copyright-holder xml:lang="ru">ФГБОУ ВО ВГМУ им. Н.Н. Бурденко Минздрава России</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/" start_date="2017-11-19"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://vestnik-surgery.com/journal/about/editorialPolicies</ali:license_ref></license></permissions><self-uri xlink:href="https://vestnik-surgery.com/journal/article/view/990">https://vestnik-surgery.com/journal/article/view/990</self-uri><abstract xml:lang="en"><p>The problems of diagnosis and treatment of acute pan-Creatine (OP) is traditionally considered one of the mostComplicated in surgical practice. This isOn the one hand, a significant increase in the frequencyIts occurrence. So, if at the beginning of the twentieth century, the OP wasHe was seen as casuistry, but nowAcute surgical diseases of the abdominal organsCavity, it is second only to acute appendicitis andAcute cholecystitis [1, 3, 4, 5, 16, 26]; Moreover, the co-The socio-economic significance of the problem lies in theThat the OP is mainly affected by persons workingOf the same age (30-50 years) [10, 11, 16, 26]. On the other hand,Although the overall lethality in OP varies from 1Up to 7% [3, 4, 10, 16], then under destructive forms itRemains at an extremely high level (from 12 to 87%), notWith a clear downward trend in recent years20 years [1, 3, 7, 10, 26].</p></abstract><trans-abstract xml:lang="ru"><p>Проблемы диагностики и лечения острого панкреатита (ОП) традиционно считаются одними из самых сложных в хирургической практике. Это обусловлено, с одной стороны, значительным ростом частоты его встречаемости. Так, если в начале ХХ века ОП описывался как казуистика, то в настоящее время среди острых хирургических заболеваний органов брюшной полости он уступает только острому аппендициту и острому холециститу [1, 3, 4, 5, 16, 26]; кроме того, со циально-экономическое значение проблемы состоит в том, что ОП в основном страдают лица работоспособного возраста (30–50 лет) [10, 11, 16, 26]. С другой стороны, хотя общая летальность при ОП колеблется от 1 до 7% [3, 4, 10, 16], то при деструктивных формах она остается на крайне высоком уровне (от 12 до 87%), не имея отчетливой тенденции к снижению за последние 20 лет [1, 3, 7, 10, 26].</p></trans-abstract><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>1.Gal'perin E.I., Dyuzheva T.G., Dokuchayev K.V. i soavt. Uzlovyye voprosy lecheniya destruktivnogo pankreatita. 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