Photodynamic therapy

Abstract


The article presents data on the high-tech method of treatment-photodynamic therapy (PDT). An overview of the history of the use of photochemical reaction in the treatment of patients is given. The mechanisms of therapeutic action of PDT, the advantages of the method in comparison with other methods of antimicrobial action are described in detail; the indications and contraindications for this method of treatment are given. The article lists used for PDT photosensitizers of different generations and laser devices capable of emitting laser radiation of the required wavelength. The overview contains information about the efficiency of the method of PDT with certain diseases. Based on the literature review, it is concluded that PDT is a modern and promising method of treatment that can significantly improve the quality of care for patients with various diseases, which are based on cell proliferation.

The proven effectiveness of the method of photodynamic therapy and its advantage over other antimicrobial treatments demonstrate the relevance of its wider introduction into clinical practice.


Dmitrii Igorevich Sazhnev

Voronezh state medical university named after N.N. Burdenko

Author for correspondence.
Email: dimitrikus@yandex.ru
ORCID iD: 0000-0003-0337-8466
SPIN-code: 5089-2193
ResearcherId: в-1928-2018
Mendeley Profile: https://www.mendeley.com/profiles/-41158/

Russian Federation, 10 Studencheskaya Street, 394036 Voronezh, Russian Federation

аспирант кафедры общей хирургии ВГМУ им. Н.Н. Бурденко

Alexandr Alexeevich Andreev

Voronezh state medical university named after N.N. Burdenko

Email: sugery@mail.ru
ORCID iD: 0000-0002-5242-6105
SPIN-code: 1394-5147
http://vrngmu.ru/academy/personnel/889/

Russian Federation, 10 Studencheskaya Street, 394036 Voronezh, Russian Federation

Ph.D., Professor of the Department of General Surgery, Deputy Director of the Institute of Surgical Infections for Research of N.N. Burdenko Voronezh State Medical University.

Alexandr Anatol'evich Glukhov

Voronezh state medical university named after N.N. Burdenko

Email: sugery@mail.ru
ORCID iD: 0000-0001-9675-7611
SPIN-code: 3821-2175

Russian Federation, 10 Studencheskaya Street, 394036 Voronezh, Russian Federation

Ph.D., Professor, head of the Department of General surgery. N. N. Burdenko

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