The change microcirculation hemostasis in patients with the peritonitis on a background the arterial hypertension

The aim was to study of microcirculation at 17 patients with peritonitis on arterial hypertension in the early postoperative
period and 15 patients with peritonitis without concomitant diseases. The concentration of ADAMTS - 13 and its inhibitor,
the level of TFPI were determined by ELISA. We studied the spontaneous and induced platelet aggregation, as well as the
definition of LTA and the degree of adgesion. In patients with peritonitis on a backround of arterial hypertension increased
rate LTA in 2,5 fold, been an increase in the degree of spontaneous aggregation in 1,6 fold and a significant increase in the
degree and rate of aggregation induced by epinephrine in 1,9 fold with respect to a clinical comparison. The level ADAMTS-13
is increased fold 1,4 of аt patients with peritonitis on a background of hypertension, the levels of TFPI increased fold 2
compared with the control group. It was established, that in patients with peritonitis on arterial hypertension has rheological
imbalance manifested revised indicators of microcirculation and hemostasis. During systemic inflammation and arterial
hypertension potentiated the deviation of the functional state of endothelial cells