Comparative Study of the Antibacterial Activity of Honey Foreign Drugs for the Treatment of Wound Infections and Domestic Native Honey


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Abstract

Relevance Increase in the number of multi-drug resistant surgical infections makes us look new evidence in relation to the known natural resources. Honey has the necessary set of properties makes it an antibacterial substance.
The purpose of the study To compare the antibacterial activity of honey products and native honey in relation to the collection of strains with extreme phenotypes of resistance to antimicrobial agents derived from surgical hospitals in Russia.
Materials and methods Investigated the antimicrobial activity of 2 honey samples recommended for clinical use in European countries and 4 samples of honey from different regions of Russia in relation to the 95 extremely resistant strains of bacteria with known mechanisms of resistance.
Results and their discussion Samples of native domestic honey were more effective against various types of microorganisms than manuka honey. Antibacterial activity is not dependent on the mechanism of resistance.
Conclusion Honey from Smolensk could become the basis for creating new effective antibacterial agent for topical treatment of wound infections caused by multidrug-resistant strains.

About the authors

Smolensk State Medical University, 28 Krupskoi Str., Smolensk, 214019, Russian Federation

Author for correspondence.
Email: vladislav.privolnev@gmail.com
PhD, Assistant Prof., Department of General Surgery, Smolensk State Medical University

Smolensk State Medical University, 28 Krupskoi Str., Smolensk, 214019, Russian Federation

Email: mapal77@mail.ru
MD, Prof. of Surgery, Chief, of General Surgery Department, Smolensk State Medical University

Smolensk State Medical University, 28 Krupskoi Str., Smolensk, 214019, Russian Federation

Email: edelsteinmv@antibiotic.ru
PhD, Chief of Laboratory of Molecular Microbiology, Institute of Antimicrobial Chemotherapy

Smolensk State Medical University, 28 Krupskoi Str., Smolensk, 214019, Russian Federation

Email: marina.sukhorukova@antibiotic.ru
PhD, senior microbiologist, Institute of Antimicrobial Chemotherapy

Smolensk State Medical University, 28 Krupskoi Str., Smolensk, 214019, Russian Federation

Email: timokhova@antiboitic.ru
microbiologist, Institute of Antimicrobial Chemotherapy

References

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