The Morphological Features of the Experimental Postsplenectomy Splenosis


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Abstract

The purpose of the study Simulation disseminated postsplenectomy splenosis in an experiment, the study of duration and frequency occurrence, morphological features of metastatic foci splenosis. Materials and methods The article presents the results of a multi-stage pilot study. The authors have developed an experimental model of disseminated postsplenectomy splenosis order to assess its morphological features. Modeling foci disseminated postsplenectomy splenosis 17 white rats line Wistar. Results and their discussion According to the results of morphological research foci splenoza can talk about significant "gistoarchitecture disorder" of the neo splenic tissue - which casts doubt on the possibility of compensation of lost body functions. A clear need for further research. Conclusion Thus, for the first time, an experimental model postsplenectomy splenosis (RF patent "Method for modeling disseminated postsplenectomy splenoza» № 2481645). The incidence of foci of disseminated postsplenectomy splenosis in rats "Wistar" was 83%. Macroscopically distinguishable pockets splenosis come to be determined by the period of 30 days after surgery. This model confirms the description of clinical cases about the possibility of self-implantation splenic tissue components on almost all body tissues.

About the authors

Moscow Research Institute of Pediatrics and Pediatric surgery, 2 Taldomskaia Str., 125412, Moscow,
Russian Federation

Author for correspondence.
Email: author@vestnik-surgery.com
MD, Prof., Deputy Director of MRI Pediatrics and Pediatric Surgery, Russian Ministry of Health Russian Federation

V. I. Razumovsky Saratov State Medical University, 112 Bol'shaia Kazach'ia Str., Saratov, 410012,
Russian Federation

Email: author@vestnik-surgery.com
PhD, Associate Prof. of Medical University "V.I. Razumovsky Saratov State Medical University", Department of pediatric surgery Russian Federation

V. I. Razumovsky Saratov State Medical University, 112 Bol'shaia Kazach'ia Str., Saratov, 410012,
Russian Federation

Email: author@vestnik-surgery.com
PhD, Associate Prof. of Medical University "V.I. Razumovsky Saratov State Medical University", Department of pediatric surgery Russian Federation

V. I. Razumovsky Saratov State Medical University, 112 Bol'shaia Kazach'ia Str., Saratov, 410012,
Russian Federation

Email: author@vestnik-surgery.com
Medical University "V.I. Razumovsky Saratov State Medical University". Research Institute of Fundamental and Clinical UroNephrology , researcher at the Department of Pathomorphology Russian Federation

V. I. Razumovsky Saratov State Medical University, 112 Bol'shaia Kazach'ia Str., Saratov, 410012,
Russian Federation

Email: sergey1klyuev@yandex.ru
Clinical resident of surgery Childhood named. NV Zakharov. Medical University "V.I. Razumovsky Saratov State Medical University Russian Federation

V. I. Razumovsky Saratov State Medical University, 112 Bol'shaia Kazach'ia Str., Saratov, 410012,
Russian Federation

Email: author@vestnik-surgery.com
Head of the Department planned pediatric surgery Pediatric Surgery Clinic Clinical Hospital S.R. Mirotvortseva, Saratov. Russian Federation

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