Features of Wounds Healing Sutured with Bioresorpable Antimicrobial Suture Material

Abstract


Relevance The use of biologically active (usually antimicrobial) suture materials in surgical operations has positive impact for tissue regeneration. Among antibacterial surgical threads issued in Russia there are no bioresorpable ones that does its development an actual problems of modern surgery and medical industry.
The purpose of the study Experimental investigation of new antimicrobial bioresorpable suture material influence for reparation processes in wounds sutured with it.
Material and methods In 60 white rat males the healing of wounds sutured with a new antimicrobial bioresorpable suture material was investigated. To control the research results the cytological and histological methods were used.
Results and their discussion It turned out that use of a new bioresorpable suture material activates the wound process both in an inflammation phase and in a proliferation and regeneration phase. It is shown by fast migration of cellular blood elements into the damage zone, by high rates of granulations formation and epithelization of wound defect. The possible mechanisms of the suture material influence for wound healing are discussed.
Conclusion The results show that the new suture material is prospective and can be used in clinical practice.

Tver State Medical Academy, 4 Sovetskaia Str., Tver., 170100, Russian Federation

Author for correspondence.
Email: koch2006@mail.ru
MD, PhD, Prof., head of General Surgery Department of Tver State Medical Academy

Tver State Medical Academy, 4 Sovetskaia Str., Tver., 170100, Russian Federation

Email: mail@vestnik-surgery.com
MD, PhD, Prof., head of Biology Department of Tver State Medical Academy

Tver State Medical Academy, 4 Sovetskaia Str., Tver., 170100, Russian Federation

Email: mail@vestnik-surgery.com
postgraduate of General Surgery Department of Tver State Medical Academy

Tver State Medical Academy, 4 Sovetskaia Str., Tver., 170100, Russian Federation

Email: mail@vestnik-surgery.com
PhD, senior lecturer of General Surgery Department of Tver State Medical Academy

Tver State Medical Academy, 4 Sovetskaia Str., Tver., 170100, Russian Federation

Email: mail@vestnik-surgery.com
senior researcher of Federal State Unatary Enterprise Russian Research Institution of Synthetic Fibre, Tver

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