About the possibility and usage perspectives of biologically active suture materials with antimicrobial and complex effect in sugery (experimental trials)

Abstract


«In vitro» experiment the antimicrobial properties of various kinds of biologically active threads (420 samples) were studied. Some of them were used «in vivo» experiment on 173 white rats using visual criteria, cytological and histological methods, electronic microscopy and tensionmetry to estimate the results of experiences. Presence of expressed and prolonged antimicrobial activity of threads containing doxycycline and ciprofloxacin was confirmed. It is established that presence in threads of doxycycline; the substance from germanium containing organic compounds group (GOC), doxycycline and GOC stimulates reparative processes in the wound model and fasten its healing. Results of the experimental researches allow to recommend suture materials with doxycycline and doxycycline and GOC to use in surgical practice.


Tver state medical Academy

Author for correspondence.
Email: author@vestnik-surgery.com

Russian Federation doctor of medical Sciences, Professor, head of Department of General surgery of Tver state medical Academy

Tver state medical Academy

Email: author@vestnik-surgery.com

Russian Federation PhD, associate Professor of General surgery of Tver state medical Academy

Tver state medical Academy

Email: author@vestnik-surgery.com

Russian Federation resident of Tver oblast Oncology dispensary

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