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Influence of heptral on the condition of the liver tissue after its resection
- Authors: 1, 1, 1
-
Affiliations:
- Орловский государственный университет
- Issue: Vol 5, No 2 (2012)
- Pages: 320-324
- Section: Original articles
- URL: https://vestnik-surgery.com/journal/article/view/138
- DOI: https://doi.org/10.18499/2070-478X-2012-5-2-320-324
- ID: 138
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Abstract
In experiments on 37 rabbits studied the influence of a controlled ischemia of the liver on its morphology and function when
administered heptral, belonging to the pharmacological group hepatoprotectors. Three series of experiments with ligation
hepatoduodenal ligament for 20 and 30 minutes and resection of the left outer lobe of the liver. It is shown that operation
without the introduction of heptral are accompanied by increased content of lipid peroxidation (LPO) in liver tissue at the
same time there are pronounced structural changes. Established that heptral reduces the severity of structural and functional
changes in the liver in conditions of prolonged ischemia body up to 30 minutes, has antioxidant properties, helping to reduce
the intensity of the processes LPO
Keywords
About the authors
Орловский государственный университет
Author for correspondence.
Email: author@vestnik-surgery.com
д.м.н., проф., зав.
кафедрой оперативной хирургии и топографиче-ской анатомии с курсом факультетской хирургии
медицинского института Орловского государствен-ного университета, заслуженный деятель науки РФ,
академик АМТН РФ; e-mail:anperkov@yandex.ru
Орловский государственный университет
Email: author@vestnik-surgery.com
к.м.н., соискатель
кафедры оперативной хирургии и топографической
анатомии с курсом факультетской хирургии меди-цинского института Орловского государственного
университета; e-mail: anperkov@yandex.ru
Орловский государственный университет
Email: author@vestnik-surgery.com
к.м.н., старший пре-подаватель кафедры пропедевтики Курского госу-дарственного медицинского университета; e-mail:
anperkov@yandex.ru
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