Comparative estimation of dynamics serum IgG after gastroplasty wounds of the liver, spleen and kidney in experiment


Cite item

Full Text

Abstract

Research is executed on 187 rabbits «Shinshilla». Under a narcosis it was spent laparotomy, in a pilot batch from the greater curvature of a stomach on a vascular leg the serous-muscular fl ap by which the wound of a liver (45 rabbits) was covered simulated lacerated-contused, spleens (45 rabbits) and the left kidney (45 rabbits) was found. In a control series were spent hepatorrhaphy (13 rabbits), wounds of a spleen (13 rabbits) and kidneys (13 rabbits) it was covered by a greater omentum, it was spent link sided nephrectomy (13 rabbits). Terms of supervision - from 1 till 360 day. Defi nition of credits IgG was carried out by reaction indirect hemagglutination with liquid erythrocytal diagnosticum on shigella Flexneri with preliminary addition L-cisztein. The received results have shown, that dynamics serum IgG after investigated operations depends on a kind of operative intervention and from plastic properties used autotransplant. Application of a serous-muscular fl ap of a stomach on a vascular pedicle promotes more intensive output IgG in a blood channel in terms of 5-7 day owing to activation by an operational trauma of immune system of a stomach, in terms of 60-90-120 day owing to effect of «deposition IgG » in required autotransplant and to less intense current of immunity during regeneration of wounds of a liver, a spleen and a kidney in comparison with hepatorrhaphy, omentoplasty and nephrectomy as follow more productive current infl ammatory- reparative process. At safe operations serum IgG it is restored in the nearest terms of the postoperative period. After gastroplasty this restoration occurs more effectively in comparison to an omentum.

About the authors

Астраханская государственная медицинская академия

Author for correspondence.
Email: olegmusatv@rambler.ru
кандидат медицинских наук, докторант кафедры оперативной хирургии с топографической анатомией Астраханской государственной медицинской академии

References

  1. Agafonov A.A. Operatsii na sloiakh zheludochnoi stenki. Avtoref. diss. …d-ra. med. nauk. Kazan'., 1972; 23.
  2. Val'ter V.G., Batchaeva L.Kh. Ispol'zovanie chasti bol'shoi krivizny zheludka pri formirovanii iskusstvennogo zheludka. Vestnik khirurgii 1964; 2: 109-112.
  3. Val'ter V.G., Zurnadzh'iants V.A., Odishelashvili G.D. Sposob ushivaniia razmozzhennykh i skal'pirovannykh ran pecheni. Biulleten' izobretenii 1994; 3: 17.
  4. Vladimirova E.S., Abakumov M.M., Dubrov E.Ia., Chernaia N.R., Vil'k A.P., Barmina T.G. Diagnostika i lechenie povrezhdenii u postradavshikh s sochetannoi travmoi. Annaly khirurgicheskoi gepatologii 2008; 2: 27-35.
  5. Zatolokina A.D. Morfologicheskie izmeneniia v pecheni posle razlichnykh vidov rezektsii i plastiki ee ranevoi poverkhnosti biologicheskimi i sinteticheskimi materialami. Avtoref. diss. kand. biol. nauk. M., 1980; 20.
  6. Zurnadzh'iants V.A. Ispol'zovanie segmenta bol'shoi krivizny zheludka v plasticheskoi khirurgii. Vestnik khirurgii 1987; 6: 94-96.
  7. Komarov I.A., Mokhov E.M. Plasticheskoe ukreplenie shvov kul'ti dvenadtsatiperstnoi kishki pri rezektsii zheludka. Khirurgiia 1983; 4: 32-35.
  8. Kravtsov S.A. Mikrokhirurgicheskaia rekonstruktsiia organov orofaringeal'noi zony zheludochno-sal'nikovym autotransplantatom u onkologicheskikh bol'nykh. Diss. kand. med. nauk. M., 2000; 162.
  9. Musatov O.V., Zurnadzhan S.A., Bogatyreva O.E. Proliferatsiia gistiotsitov pri eksperimental'nykh ranakh pecheni, selezenki ili pochki posle plastiki fragmentom zheludka. Eksperimental'naia i klinicheskaia gastroenterologiia 2010; 5: 43-47.
  10. Musatov O.V., Zurnadzhan S.A., Khairulin Iu.Kh. Dinamika tkanevogo IgG posle gastroplastiki ran pecheni, selezenki i pochki v eksperimente. Vestnik Volgogradskogo gosudarstvennogo meditsinskogo universiteta 2009; 4: 72 - 75.
  11. Musinov I.M. Angioarkhitektonika zheludka i ee vliianie na proiavlenie krovotechenii. Aktual'nye voprosy klinicheskoi anatomii i operativnoi khirurgii. Materialy 3-i Vserossiiskoi konferentsii s mezhdunarodnym uchastiem. SPb.- Izd-vo SPbGMU., 2003; 154-157.
  12. Odishelashvili G.D. Gemostaz pri povrezhdeniiakh pecheni, selezenki, pochek i podzheludochnoi zhelezy: Avtoref. dis. d-ra med.nauk. M., 1996; 33.
  13. Pavlov I.P. Lektsii po fiziologii. M.: Izd-vo AN SSSR 1952; 492.
  14. Popov V.A. Gemostaz i germetizatsiia shvov (operatsii na vnutrennikh organakh). M. GEOTAR-Media., 2008; 320.
  15. Potashov L.V., Berlin L.V., Klimashevskii V.V., Sedov V.M. Regeneratsiia slizistoi obolochki zheludka v usloviiakh massivnoi krovopoteri. Arkhiv anatomii, gistologii i embriologii 1976; 2: 65-68.
  16. Savenkov P.A. Plasticheskoe ukrytie «trudnoi» kul'ti dvenadtsatiperstnoi kishki pri rezektsii zheludka po Bil'rot-II: Avtoref. diss. …kand.med.nauk. Astrakhan'., 2005; 19.
  17. Sibul' U.F. Arterial'nye sosudy zheludka i ikh znachenie pri rasshirennoi rezektsii: Avtoref. diss. kand.med.nauk. L. Tallin., 1966; 16.
  18. Simorot N.I. Krovenosnaia sistema zheludochno-kishechnogo trakta i ikh adaptatsionnye svoistva pri rezektsiiakh i gastrektomiiakh: Diss. …d-ra med. nauk. M. -Grodno., 1972; 454.
  19. Talanian K.A. Sravnitel'naia otsenka nekotorykh sposobov ostanovki krovotecheniia pri povrezhdeniiakh selezenki: Diss. …kand. med. nauk. Astrakhan'., 2004; 118.
  20. Fedoseeva V.N., Poriadin G.V., Koval'chuk L.V., Cheredeev A.N., Kogan V.Iu. Rukovodstvo po immunologicheskim i allergologicheskim metodam v gigienicheskikh issledovaniiakh. M.- Promedek., 1993; 320.
  21. Tsybyrne K.A., Lipovan V.G., Bargan M.A. Sravnitel'naia otsenka nekotorykh metodov gemostaza pri operatsiiakh na pecheni i selezenke. Khirurgiia 1987; 7: 45 - 49.
  22. Shashin S.A. Sravnitel'naia otsenka nekotorykh metodov plastiki defektov briushnoi aorty i nizhnei poloi veny: Avtoref. diss. d-ra med. nauk.- Astrakhan'.,2010; 35.
  23. Close C.E., Anderson P.D., Edwards G.A., Mitcell M.E., Dewan P.A. Auto augmentation gastrocystoplasty: further studies of the sheep model. BJU International 2004; 4: 658-662.
  24. Donnellan S.M., Ryan A.G., Bolton D.M. Gastric patch pyeloplasty: development of an animal model to produce upper tract urinary acidifi cation for treated struvite urinary calculi. Journal of Urology 2001; 2: 684-687.
  25. Kamei Y., Torii S. A new composite gastric seromuscular and omental pedicle fl ap. Annals of Surgery 1994; 1: 97-101.
  26. Keller M.S. Blunt injury to solid abdominal organs. Seminars in Pediatric Surgery 2004; 2: 106-111.
  27. Patel R.S., Makitie A.A., Goldstein D.P., Gullane P.J., Brown D., Irish J., Gilbert R.W. Morbidity and functional outcomes following gastro-omental free fl ap reconstruction of circumferential pharyngeal defects. Head Neck 2009; 5: 655-663.
  28. Ridereau - Zins C., Lebigot J., Bouhours G., Gasa C., Aubé C. Traumatismes abdominaux: les lesions elementaires. Journal of Radiology 2008; 11: 2: 1812-1832.
  29. Shoham N., Sweed Y. Abdominal trauma in childhood - the conservative approach in 95 cases. Harefuah 1999; 9: 672-677.
  30. Zachariou Z. Amniotic membranes as prosthetic material: experimental utilization data of a rat model. Journal of Pediatric Surgery 1997; 10: 1458-1463.

Supplementary files

Supplementary Files
Action
1. JATS XML
Download

Copyright (c) 2010 .

Creative Commons License
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

This website uses cookies

You consent to our cookies if you continue to use our website.

About Cookies