Postmortem Tissue Analysis of Opisthorchiasis Papillitis

Abstract


The purpose of the study The research is aimed at examining histologic and morphometric aspects of the major duodenal papilla which has opisthorchiasis invasion.
Materials and methods The research uses cadaveric material taken in the department of morbid anatomy of Surgut regional clinical hospital. All the cases which were included in the study (98 dead patients) had the direct evidence of infection with opisthorchiasis according to post-mortem examination together with information about the length of opisthorchiasis invasion during the life of the patients. The control group included 30 dead patients without the pathology of hepatobiliary tract. The study showed that the opisthorchiasis invasion brings about successive changes in papilla tissues which can be divided into three stages according to morphological criteria - the adenomatous stage, the adenofibrous stage and the sclerotic stage (the names reflect the nature of changes). The analysis of the material was carried out using statistical approach.
Results and their discussion Morphological research with sufficient evidence demonstrated specific changes which take place in the tissues of the major duodenal papilla at different stages of papillitis. It also determined that the luminal diameter of papilla is the indicator of these changes.
Conclusion The general tendency of changes in the major duodenal papilla brought about by opesthorchiasis can be described as progressive degradation of morphological structures that constitute the tissue of the major duodenal papilla, which results in functional failure of the given anatomical structure.

Surgut Regional Clinical Hospital, 14 Energetikov Str., Surgut, 624000, Russian Federation

Author for correspondence.
Email: author@vestnik-surgery.com
PhD, assoc. prof. of chair of hospital surgery, head of the Oncology Department budgetary institution "Surgut Regional clinical hospital"

Surgut Regional Clinical Hospital, 14 Energetikov Str., Surgut, 624000, Russian Federation

Email: author@vestnik-surgery.com
MD, Prof., supernumerary chief specialist in Surgery budgetary institution "Surgut Regional clinical hospital"

Surgut Regional Clinical Hospital, 14 Energetikov Str., Surgut, 624000, Russian Federation

Email: author@vestnik-surgery.com
PhD, doctor Surgery Department of budgetary institution "Surgut Regional clinical hospital"

Surgut Regional Clinical Hospital, 14 Energetikov Str., Surgut, 624000, Russian Federation

Email: author@vestnik-surgery.com
doctor Pathology Department of budgetary institution "Surgut Regional clinical hospital"

Surgut Regional Clinical Hospital, 14 Energetikov Str., Surgut, 624000, Russian Federation

Email: author@vestnik-surgery.com
doctor Pathology Department of budgetary institution "Surgut Regional clinical hospital"

  1. Al'perovich B.I., Revskoi A.Iu., Brazhnikova N.A. Lechenie striktury zhelchnyh putej pri opistorhoze. [Treatment of biliary tract strictures at opisthorchiasis]. Khirurgiia, 1983; 8: 40-46. - (in Russ.).
  2. Vil'gel'm V.D., Beliavskii A.R., Khriachkov V.V. Profil' patologii gepatobiliarnoj sistemy i podzheludochnoj zhelezy korennogo i prishlogo naseleniya Priob'ya. [Profile pathology of the hepatobiliary system and pancreas in native and alien population Priobye]. Aktual'nye voprosy neotlozhnoi khirurgii. Sbornik nauchnykh trudov Vyezdnogo plenuma Problemnoi komissii "Neotlozhnaia khirurgiia" Mezhvedomstvennogo Nauchnogo soveta po khirurgii RAMN i Minzdrava Rossii [Topical issues of urgent surgery. Collection of scientific works of outbound plenum Problem Commission "Emergency surgery" Interdepartmental Scientific Council of Surgery RAMS and the Russian Ministry of Health]. Moscow, 2003; 3-7. - (in Russ.).
  3. Zerchaninov L.K. Materialy nauchnoi konferentsii po meditsinskoi parazitologii [Materials of scientific conference on medical parazitology]. Tiumen', 1964; 87-91. - (in Russ.).
  4. Zigan'shin R.V. Khirurgicheskie oslozhneniia opistorkhoza [Surgical complications opisthorchiasis]. Tomsk: STT, 2003; 120. - (in Russ.).
  5. Zigan'shin R.V., Bychkov V.G. Biliarnaya gipertenziya u pacientov s opistorhozom. [Biliary hypertension in patients with opisthorchiasis]. Vestnik khirurgii im. Grekova, 1984; 12: 29-33. - (in Russ.).
  6. Zubov N.A. Patologicheskaia anatomiia opistorkhoza i ego oslozhnenii [Pathological anatomy opistorhoza and its complications]. Doct. Diss. Med. Sci. Sverdlovsk, 1973; 15. - (in Russ.).
  7. Zubov N.A., Glumov V.Ia. Dinamika morfologicheskih i gistohimicheskih izmenenij podzheludochnoj zhelezy v rannej faze ehksperimental'nogo opistorhoza. [Dynamics of morphological and histochemical changes of the pancreas in the early phase of experimental opisthorchiasis]. Meditsinskaia parazitologiia i parazitarnye bolezni, 1969; 2: 169–173. - (in Russ.).
  8. Zubov N.A., Zubkov V.G. Giperplasticheskie izmeneniya bol'shogo duodenal'nogo sosochka pri opistorhoze u cheloveka. [Hyperplastic changes papillary human opisthorchiasis]. Arkhiv patologii, 1983; 1: 34-38. - (in Russ.).
  9. Kul'chiev A.A. Khirurgicheskoe lechenie oslozhnenii opistorkhoznogo skleroziruiushchego pankreatita [Surgical treatment of sclerosing pancreatitis complicated with opisthorchiasis. Cand. Diss. Med. Sci.]. Sverdlovsk, 1980; 15. - (in Russ.).
  10. Tret'iakov A.M., Zhukov B.G. Operacionnaya rentgenomanometriya biliarnogo trakta u bol'nyh s oslozhnennym opistorhozom. [Operating rentgenomanometriya biliary tract in patients with complicated opisthorchiasis]. Opistorkhoz cheloveka [Proc. of the Interregional Scientific and Practical Conference on "Opisthorchiasis man"]. Tomsk, 1979; 184-186. - (in Russ.).
  11. Glantz S.A. Primer of Biostatistics, 4th Edition. McGraw-Hill. New York, 1997; 473.

Views

Abstract - 89

PDF (Russian) - 43

PlumX

Dimensions


Copyright (c) 2015 ., ., ., ., .

Creative Commons License
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

This website uses cookies

You consent to our cookies if you continue to use our website.

About Cookies