Non-Hodgkin Lymphoma on the Base of Autoimmune Tireoidit


The article discussed some problems in diagnostics and specific issues of treatment of Hodgkins and non-Hodgkins lymphomas (NHL) of thyroid gland, more than 30 congenital diseases, growing from mature B, T and NK-cells, which are different in morphology, clinical symptoms and treatment’s results, especially in case of combination of NHL and autoimmune thyroiditis. Correlation between autoimmune thyroiditis and the development of primary non-Hodgkin's lymphoma of the thyroid gland remains unclear. Authors pointed unsatisfaction with cytological methods of diagnostics. The authors recommend a comprehensive study of patients for diagnostic of thyroid gland diseases, including ultrasonic needle biopsy with cytology analysis, CT scan of the thyroid gland and anterior mediastinum, thyroid gland ultrasound, scintigraphy of the thyroid gland, hormonal status investigation. Open biopsy following by histological examination and necessity of differentiation with non- differentiated cancer of thyroid gland, autoimmune thyroiditis and Ridel’s goiter are also recommended. In case of rapid growth of the thyroid gland, significant heterogeneity of structure, absence of organ’s mobility in combination with cytologically proved "Hurthle’s autoimmune thyroiditis", it is necessary to exclude NHL. Besides surgical treatment authors recommend chemotherapy.

City Hospital №2, Krasnodar, Russian Federation

Author for correspondence.
Ph.D., Krasnodar City Hospital №2, Department of Endocrine surgery

Rostov State Medical University, Rostov-on-Don, Russian Federaion

professor, D.Sc., Rostov State Medical University, Head of the Department of General Surgery

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