The Effectiveness of Systemic Thrombolysis in the Treatment of Massive Pulmonary Embolism

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Abstract

The article presents a case of timely diagnosis and successful treatment of massive pulmonary embolism in a young man suffering from obesity, hypertension and osteochondrosis of the lumbar spine. The disease was manifested with symptoms of acute respiratory failure, hemodynamics was stable. Laboratory tests revealed an increase in the level of D-dimer and hypercoagulation. Electrocardiographic examination revealed signs of overloading of the right ventricle, and echocardiography revealed pulmonary hypertension of the 2nd degree. Ultrasound examination of the venous system of the lower extremities detected that the cause of the embolism was the migration of a blood clot from a thrombosed femoral vein. The diagnosis was confirmed during computed tomography of the lungs with intravenous contrast. Thrombolytic therapy was performed with alteplase in standard dosages. The patient underwent anticoagulant therapy for 3 months.

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About the authors

Boris S. Sukovatykh

Kursk State Medical University

Author for correspondence.
Email: SukovatykhBS@kursksmu.net
ORCID iD: 0000-0003-2197-8756

M.D., Professor, Head of the Department of General Surgery

Russian Federation, Kursk

Maxim Y. Gordov

Kursk City Clinical Hospital of Emergency Medical Care

Email: maks_gordov@mail.ru

Head of the Vascular Surgery Department

Russian Federation, Kursk

Inna V. Larina

Kursk City Clinical Hospital of Emergency Medical Care

Email: maks_gordov@mail.ru

surgeon of the Vascular Surgery Department

Russian Federation, Kursk

Nelly M. Valuyskaya

Kursk State Medical University

Email: valuiskayanm@kursksmu.net

Ph.D., Associate Professor of the Department of General Surgery

Russian Federation, Kursk

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Supplementary files

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2. Fig. 1. Tomogram with contrast enhancement of the lungs of patient L. A thrombus with occlusion of 70% of its lumen is detected in the lumen of the pulmonary artery (arrow).

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Copyright (c) 2024 Sukovatykh B.S., Gordov M.Y., Larina I.V., Valuyskaya N.M.

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