Patient’s therapy of the minor cardiac output syndrome by strong solutions of glucose with high doses of insulin in early postoperative period after coronary artery bypass graft surgery


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Abstract

Cardiac decompensation leads to fast deterioration of energy supplies in cardiac muscle. The main source of energy supply is glucose. Stress results in decrease of utilization of carbohydrates.  Insulin infusion in the dose of 2,5 units kg./body mass and glucose in the dose of 1g/kg.body mass improves indexes of intramuscular hemodynamics: cardiac index exceeds 2,3 liter/ min/m², ejection fraction exceeds 45%. Therapy of cardio surgery patients by glucose insulin potassium mixture (GIPM) is an effective treatment of the minor cardiac output syndrome and causes the improvement of systolic and diastolic function of cardiac muscle.

About the authors

Воронежская областная клиническая больница №1 Воронежская государственная медицинская академия им. Н.Н.Бурденко

Author for correspondence.
Email: author@vestnik-surgery.com
.

Воронежская областная клиническая больница №1 Воронежская государственная медицинская академия им. Н.Н.Бурденко

Email: canc@vsma.ac.ru
.

References

  1. Bruemmer-Smith S., Avidan M.S., Harris B. et al. Glucose, insulin and potassium protection during cardiac surgery. Br. J. Anaesth. 2002; 88: 489 495. 9. Fath-Ordoubadi F., Beatt K.J. Glucose-insulin-potassium therapi for treatment of acute myocardial infarction: an overview of randomizet placebo-controlled trials. Circulation. 1997; 96: 1152-1156.

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