The Morphological Features of Reparative Process after Sutureless Plasty of Abdominal Wall with Mesh Use


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Relevance The basic surgical procedure in hernia repair of abdominal wall is the tension-free plasty with mesh use. The study of nearest results after mesh plasty with different methods of its fixation to the abdominal wall is actual question of modern hernia repair. The purpose of the study Eexperimental research of morphological features of reparative process after sutureless plasty with mesh use. Matherials and methods We modeled the intraperitoneal plasty with mesh use in rabbits. The polypropylene, polyvinylidenfluoride and reperene endoprosthesis were used. In basic group the sutureless technique was performed. In control group the typical fixation of mesh was performed. The area of implantation was studied with optical microscopy in 30 – 180 days after operation. Results and their discussion The stages of reparative process were common for all mesh types and surgical techniques. In basic group the area of neoperitoneum was maximal, the vascularization was optimal. We noted in basic group low level of collagen, but neoperitoneum was complete and no fenestrated. The connective tissue was found soft in the basic group in contrast with control. Morphological changes were estimated as uncomplicated flow of reparative process after mesh implantation. The sutureless technique is optimal for IPOM plasty. Conclusion The patterns of current repair process after IPOM plasty are common to all the studied implants and methods of its fixation. Features and results depend on the material of mesh and the method of fixing the endoprosthesis. Free positioning of the mesh in the plasty area associated with minimal presence of an inflammatory component, adequate angiogenesis, and the formation of soft connective tissue and high grade of neoperitoneum.

About the authors

Nizhny Novgorod State Medical Academy, Nizhny Novgorod, Russian Federation;
Scientific Research Institute of Applied and Fundamental Medicine, Nizhny Novgorod, Russian Federation

Email: author@vestnik-surgery.com
MD, Professor of the Department of Hospital Surgery named after B.A. Korolev, Nizhny Novgorod State Medical Academy

Nizhny Novgorod State Medical Academy, Nizhny Novgorod, Russian Federation;
Scientific Research Institute of Applied and Fundamental Medicine, Nizhny Novgorod, Russian Federation

Email: author@vestnik-surgery.com
Surgeon of the City Hospital № 35 of Nizhny Novgorod

Nizhny Novgorod State Medical Academy, Nizhny Novgorod, Russian Federation;
Scientific Research Institute of Applied and Fundamental Medicine, Nizhny Novgorod, Russian Federation

Email: author@vestnik-surgery.com
Doctor of Biological Sciences, Director of the Morphology Department of the Central Research Laboratory of the Research Institute of Applied and Fundamental Medicine, Nizhny Novgorod State Medical Academy

Nizhny Novgorod State Medical Academy, Nizhny Novgorod, Russian Federation;
Scientific Research Institute of Applied and Fundamental Medicine, Nizhny Novgorod, Russian Federation

Author for correspondence.
Email: author@vestnik-surgery.com
Candidate of Biological Sciences, Senior Researcher of the Morphology Department of the Central Research Laboratory of the Research Institute of Applied and Fundamental Medicine, Nizhny Novgorod State Medical Academy

Nizhny Novgorod State Medical Academy, Nizhny Novgorod, Russian Federation;
Scientific Research Institute of Applied and Fundamental Medicine, Nizhny Novgorod, Russian Federation

Email: author@vestnik-surgery.com
Candidate of Biological Sciences, Senior Researcher of the Morphology Department of the Central Research Laboratory of the Research Institute of Applied and Fundamental Medicine, Nizhny Novgorod State Medical Academy

Nizhny Novgorod State Medical Academy, Nizhny Novgorod, Russian Federation;
Scientific Research Institute of Applied and Fundamental Medicine, Nizhny Novgorod, Russian Federation

Email: author@vestnik-surgery.com
Candidate of Biological Sciences, Senior Researcher of the Morphology Department of the Central Research Laboratory of the Research Institute of Applied and Fundamental Medicine, Nizhny Novgorod State Medical Academy

Nizhny Novgorod State Medical Academy, Nizhny Novgorod, Russian Federation;
Scientific Research Institute of Applied and Fundamental Medicine, Nizhny Novgorod, Russian Federation

Email: author@vestnik-surgery.com
Surgeon of the City Hospital № 35 of Nizhny Novgorod

Nizhny Novgorod State Medical Academy, Nizhny Novgorod, Russian Federation;
Scientific Research Institute of Applied and Fundamental Medicine, Nizhny Novgorod, Russian Federation

Email: author@vestnik-surgery.com
Candidate of Biological Sciences, Head of the Experimental Modeling Group of the Morphology Department of the Central Research Laboratory of the Research Institute of Applied and Fundamental Medicine, Senior Lecturer of the Department of Normal Physiology named after N.Yu. Belenkov, Nizhny Novgorod State Medical Academy

Nizhny Novgorod State Medical Academy, Nizhny Novgorod, Russian Federation;
Scientific Research Institute of Applied and Fundamental Medicine, Nizhny Novgorod, Russian Federation

Email: author@vestnik-surgery.com
Candidate of Biological Sciences, Researcher at the Department of Neurophysiology and Experimental Modeling of the Morphology Department of the Central Research Laboratory of the Research Institute of Applied and Fundamental Medicine, Assistant of the Department of Normal Physiology named after N.Yu. Belenkov, Nizhny Novgorod State Medical Academy

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