Objectication of the severity of the condition patients with advanced peritonitis by formulas clinical biochemical indices

Peritonitis remains one of the central problems of modern surgery, as evidenced by mortality rate, reaching in some groups of patients - 40% or more. The study was a retrospective analysis of 336 stationary records of patients with acute peritonitis, of which 153 - and 183 deaths - the survivors. The aim of the study was to improve treatment outcomes in patients with acute peritonitis by developing more objective severity of patients, based on the use of formulas of clinical and biochemical parameters. To assess the severity of patients with peritonitis was used universal technique for the formula of clinical and biochemical indicators: measured deviation of the studied indicator of the level of standards and then determined the degree of clinical and laboratory disorders, with each degree of disorder of clinical and laboratory parameters corresponds to the change rate over the previous 15%. Analysis of clinical and laboratory parameters was conducted at admission, on the second, third, fifth and seventh day of hospitalization. Analysis of clinical and biochemical disorders showed differences in the reliability of the studied parameters of the deceased and surviving patients with acute peritonitis. The prognostic significance can be considered: Entry - increasing levels of bilirubin, urea, creatinine reduction, on the second day - increasing the level of bilirubin, urea, creatinine reduction, on the third day - increased levels of transaminases, bilirubin, urea, on the fifth day - increasing levels of bilirubin, urea, on the seventh per day - increasing levels of bilirubin, urea. Noteworthy is the lack of reliability of the differences between surviving and deceased patients in assessing the level of hemoglobin, hematocrit, glucose, VC, plasma amylase and total protein, the dynamics of change which was considered uninformative.

Peritonitis, abdominal sepsis, clinical and biological indicators.