Sorbtion Methods Correction Metabolic Disorders for Mediastinitis


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Abstract

Relevance The urgency is not due to a tendency to reduce the number of patients with acute mediastinitis. An important moment of the correction of endotoxemia, which is celebrated by introducing diseases is enterosorption. Unlike hemosorption plasmapheresis eneterosorbtion is noninvasive and does not require specially trained personnel, has no absolute contraindications, clinically significant side effects. The purpose of the study To assess enterosorbtion patients with acute mediastinitis using enterosorbent "Litovit." Materials and methods In the treatment of 29 patients with acute mediastinitis in 13 addition to the primary treatment method used enterosorbtsii drug "Litovit." All patients underwent incision and drainage of the mediastinum vneplevralnym way. Enterosorbent "Litovit" appointed for 2 - 3 days after surgery, up to the transfer of the patient from the intensive care unit in the profile department. The route of administration through a nasogastric tube or gastrostomy. Results and their discussion Inclusion in a comprehensive program of treatment in the early postoperative period enterosorption using drugs such as "Litovit" in the treatment of patients with acute mediastinitis increased the effectiveness of intensive therapy. Application enterosorbtion accelerated the rate of decline in the inflammatory process and improve liver function. Application enterosorbtion reduced the rate of final products lopoperoxidation and increase the antioxidant system. Conclusions Use as a sorbent "Litovit" accelerated the rate of decline in the inflammatory process, improve the treatment of patients with acute mediastinitis.

About the authors

Novosibirsk State Medical University, Novosibirsk, Russian Federation;
State Novosibirsk Regional Hospital, Novosibirsk, Russian Federation

Author for correspondence.
Email: author@vestnik-surgery.com
professor, doctor of medical science, head department hostpital and children’s surgery Novosibirsk State Medical University

Novosibirsk State Medical University, Novosibirsk, Russian Federation;
State Novosibirsk Regional Hospital, Novosibirsk, Russian Federation

Email: author@vestnik-surgery.com
doctor of medical science, head department hostpital and children’s surgery Novosibirsk State Medical University, thoracic surgeon, endoscopist Department of Thoracic Surgery Novosibirs State Regional Hospital

Novosibirsk State Medical University, Novosibirsk, Russian Federation;
State Novosibirsk Regional Hospital, Novosibirsk, Russian Federation

Email: author@vestnik-surgery.com
ordinator department hostpital and children’s surgery Novosibirsk State Medical University

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